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1687 articles
October 202624
Anaphylaxis Following Intravenous Methylprednisolone Sodium Succinate: A Case Report.
A 45-year-old woman with rheumatoid arthritis developed generalized pruritic erythema and raised lesions, dyspnea, hypoxemia, bradycardia, and reduced consciousness within 5 minutes of starting intravenous…
Impact of Side-to-Side Versus End-to-Side Gastrojejunostomy on the Rate of Delayed Gastric Emptying After Pancreatoduodenectomy (IPAD study): A Randomized Controlled Trial.
The IPAD study was a prospective, open-label randomized trial at two high-volume pancreatic centers in France, comparing side-to-side with end-to-side gastrojejunostomy in adults undergoing pancreatoduodenectomy for…
A phase III randomized study: Immunogenicity and safety of a quadrivalent meningococcal conjugate vaccine in healthy adults, adolescents, and children in India and healthy adolescents and children in South Africa.
This Phase III randomized controlled trial assessed the immunogenicity and safety of a single dose of MenACYW-TT in healthy adults, adolescents, and children in India and in adolescents and children in South Africa.
Dynamic change patterns in suicidal ideation differ in Brief Cognitive Behavioral Therapy (BCBT) and Present-Centered Therapy (PCT).
This randomized clinical trial examined how five dimensions of suicidal ideation changed during Brief Cognitive Behavioral Therapy (BCBT) versus Present-Centered Therapy (PCT) among high-risk U.S.
The utility of magnetic resonance imaging of the spinal cord in paediatric transverse myelitis: A systematic review.
This systematic review assessed spinal cord MRI findings, agreement with CSF inflammation, and prognostic associations in children with monophasic acute transverse myelitis.
Adjunctive neuromuscular electrical stimulation and cognitive-motor interference during gait in older inpatients.
This exploratory analysis of a pragmatic pilot trial examined whether adjunctive neuromuscular electrical stimulation (NMES) was associated with changes in cognitive-motor interference during gait among older inpatients…
Nutraceuticals and phytoceuticals in the treatment of bipolar disorder: A systematic review and network meta-analysis.
This systematic review and network meta-analysis assessed randomized controlled trials of nutraceuticals and phytoceuticals for bipolar disorder. Twenty-eight trials involving 2,222 participants evaluated 22 treatments.
Preoperative CA15-3 as a predictor of axillary lymph node metastasis and prognosis in women with breast cancer: a GRADE-assessed systematic review and meta-analysis.
This GRADE-assessed systematic review and random-effects meta-analysis examined cohort studies of preoperative CA15-3 in women with breast cancer, assessing survival and metastatic outcomes.
Mechanical Thrombectomy Versus Anticoagulation Alone in Intermediate-High Risk PE: Improved Functional 90-Day Outcomes in STORM-PE RCT.
STORM-PE was a multicentre randomised trial comparing computer-assisted vacuum thrombectomy (CAVT) plus anticoagulation with anticoagulation alone in 100 patients with acute intermediate-high-risk pulmonary embolism.
No-Stent Management of High Coronary Thrombus Burden in Young Patients with STEMI: A Four-Case Series.
The report describes four young male patients (≤50 years old) presenting with STEMI and a large coronary thrombus without clearly demonstrated flow-limiting severe atherosclerotic stenosis.
Interference of iron deficiency in glycated hemoglobin testing and its clinical implications: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of iron deficiency anemia (IDA) and latent iron deficiency (LID) on glycated hemoglobin (HbA1c) concentrations.
Repeated remimazolam sedation for interstitial brachytherapy in cervical cancer: a randomized controlled trial.
This randomized controlled trial evaluated the safety and efficacy of repeated remimazolam sedation compared to propofol in 100 patients with cervical cancer undergoing interstitial brachytherapy.
N-acetylcysteine mouthwash for prevention of oral mucositis in hematopoietic cell transplant recipients: a double-blind randomized controlled trial.
This double-blind randomized controlled trial evaluated the efficacy of N-acetylcysteine (NAC) mouthwash in preventing oral mucositis (OM) in 106 hematopoietic cell transplant (HCT) recipients.
Image-Guided Cervicotomy and Recurrent Laryngeal Nerve Reinnervation in Zone II Glass Neck Trauma: A Case Report.
A 45-year-old woman with penetrating neck trauma from glass fragments presented hemodynamically stable, without airway compromise. Imaging revealed multiple retained glass foreign bodies but no major vascular injuries.
Improvement of image quality and diagnostic accuracy of novel ferumoxytol-enhanced magnetic resonance coronary angiography: compared to non-contrast enhanced imaging.
This retrospective analysis of a prospective clinical trial compared ferumoxytol-enhanced with non-contrast coronary magnetic resonance angiography (CMRA) in 29 patients, using invasive coronary angiography as the…
Stepwise dual antiplatelet therapy de-escalation versus standard therapy for 12 months in patients with bifurcation lesions undergoing drug-coated balloon angioplasty: Insights from the REC-CAGEFREE II trial.
This prespecified subgroup analysis of the multicentre randomised REC-CAGEFREE II trial compared stepwise dual antiplatelet therapy (DAPT) de-escalation with 12-month standard DAPT in patients with acute coronary…
Concordance of Microbiological and Histopathological Examination of Bone Biopsies in Diagnosing Diabetic Foot Osteomyelitis, a Systematic Review.
This systematic review evaluated the diagnostic concordance of histopathology and microbiology in bone biopsies from 308 adults with diabetic foot osteomyelitis (DFO).
Bone Anabolic Treatment in Patients With Chronic Kidney Disease: A Systematic Review.
This systematic review evaluated the efficacy and safety of anabolic parathyroid hormone (PTH) treatments in patients with chronic kidney disease (CKD) Stages 4-5D.
Vitamin D Supplementation and Mortality in the Elderly: A Review of a Meta-Analysis of Randomized Controlled Trials Using the REB Method.
This meta-analysis reviewed 25 randomized controlled trials (RCTs) to evaluate the impact of vitamin D supplementation on mortality in individuals aged 75 and older.
Haemodynamic and neurophysiological assessments for 2-year outcome prediction in neonates with hypoxic-ischaemic encephalopathy treated with therapeutic hypothermia: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the prognostic accuracy of amplitude-integrated electroencephalography (aEEG), cerebral near-infrared spectroscopy (cNIRS), and targeted neonatal echocardiography…
Learning curves in robotic and laparoscopic colorectal surgery: a systematic review.
This systematic review evaluated learning curves in laparoscopic and robotic colorectal surgery, analyzing 114 studies with 167 learning-curve analyses.
The learning curve of robotic pancreatoduodenectomy: a systematic review of learning curve assessment methodologies, proficiency thresholds, training pathways and clinical outcomes.
This systematic review evaluated the learning curve of robotic pancreatoduodenectomy (RPD) across 42 studies, focusing on methodologies, proficiency thresholds, and outcomes.
The Therapeutic Potential of MicroRNAs Delivered By Mesenchymal Stem Cells in Parkinson's Disease, Alzheimer's Disease, and Stroke: A Systematic Review of Preclinical Studies.
This systematic review evaluated 37 preclinical studies on the therapeutic potential of mesenchymal stem cells (MSCs) and their derived microRNAs (miRNAs) in Parkinson's disease, Alzheimer's disease, and stroke.
The impact of intratumor heterogeneity on outcome and resistance to therapy in primary breast cancer: a systematic review.
This systematic review examines the impact of intratumor heterogeneity (ITH) on chemotherapy resistance in primary breast cancer, analyzing 12 studies across various tumor subtypes.
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