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782 articles
September 202624
Malignant pertussis in a young infant.
A young infant presented with malignant pertussis, characterized by extreme leucocytosis and respiratory failure, alongside additional bloodstream infections during hospitalization.
Safety and immunogenicity of mRNA-1345 revaccination at least 12 months following primary vaccination with a licensed protein subunit RSV vaccine.
This phase 3 clinical trial assessed the safety and immunogenicity of revaccination with mRNA-1345 in adults aged ≥60 years, at least 12 months after initial vaccination with a licensed protein subunit RSV vaccine.
Impact of CD4 T cell counts on the immunogenicity and safety of the recombinant zoster vaccine in people living with HIV.
This non-randomized clinical trial assessed immunogenicity and safety of two doses of recombinant zoster vaccine (RZV) in virologically suppressed people living with HIV (PLWH) receiving antiretroviral therapy…
Subcutaneous Myiasis After Travel: Dynamic Doppler Ultrasonography as a Diagnostic Clue.
To describe dynamic ultrasonographic findings in travel-associated subcutaneous myiasis.
HBsAg decline and clearance with peg-IFN therapy added to nucleos(t)ide analogues: an individual participant data meta-analysis of prospective trials (PROSPER).
This meta-analysis evaluated the impact of peg-interferon (peg-IFN) therapy added to nucleos(t)ide analogue (NA) treatment in chronic hepatitis B patients.
Expediting a UNIVERSAL first-line regimen of a dolutegravir-emtricitabine-tenofovir alafenamide fixed-dose ratio for children living with HIV older than 4 weeks: a 24-week, open-label, single-arm, phase 1-2, pharmacokinetic, safety, and antiviral activity trial.
The UNIVERSAL1 trial evaluated the pharmacokinetics, safety, and antiviral activity of a fixed-dose combination of dolutegravir, emtricitabine, and tenofovir alafenamide in children aged 28 days to 10 years with HIV.
Bilingual infographics improve clinical communication and health outcomes among Latino persons with HIV: A multi-site mixed methods study with a randomized controlled trial.
This multi-site randomized controlled trial evaluated the use of bilingual infographics to improve clinical communication and health outcomes among Latino persons with HIV (LPWH).
Changes in sexual behavior among women in studies evaluating the dapivirine vaginal ring for HIV prevention.
This randomized controlled trial analyzed sexual behavior changes among women participating in the dapivirine vaginal ring studies, MTN 020/ASPIRE and MTN-025/HOPE.
Empirical Meropenem Versus Piperacillin/Tazobactam for Critically Ill Adults With Sepsis: Feasibility of a Randomised Trial.
The EMPRESS trial is an ongoing randomized controlled trial assessing the feasibility of comparing empirical meropenem versus piperacillin/tazobactam in critically ill adults with sepsis.
Clinical efficacy, immunogenicity and safety of RTS,S/AS01, R21/Matrix-M and candidate malaria vaccines in children: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy, immunogenicity, and safety of malaria vaccines in children under 18 years, analyzing 56 trials with 134,424 participants.
Association between sexual violence and HIV among sexual and gender minorities in low-resource settings: A meta-analysis.
This systematic review and meta-analysis pooled observational evidence on sexual violence and HIV infection among sexual and gender minorities in low-resource settings.
Mycobacterial infections and recurrent osteomyelitis in a patient with an autosomal dominant mutation in IFN-gamma receptor 1 with overexpression of the receptor.
A Mexican man developed severe BCGitis in early childhood, followed by recurrent disseminated mycobacterial infections and vertebral osteomyelitis involving several species.
Tuberculosis presenting as dual immune dysregulation: Evans syndrome and haemophagocytic lymphohistiocytosis.
A middle-aged man with no prior health issues presented with a month-long history of fever, dry cough, weight loss, and worsening breathlessness.
Antimicrobial photodynamic therapy mediated by phenothiazine photosensitizers against Candida albicans and Candida auris: a systematic review.
This systematic review evaluated the efficacy of phenothiazine-mediated antimicrobial photodynamic therapy (aPDT) against Candida albicans and Candida auris in in vitro studies.
The platform trial in COVID-19 priming and BOOsting (PICOBOO): The reactogenicity of nine licensed COVID-19 vaccines delivered in immunocompetent adults.
The PICOBOO trial evaluated the reactogenicity of nine licensed COVID-19 vaccines in immunocompetent adults aged over 12 years.
Persistence of immune responses 5 years after vaccination with a single dose of typhoid conjugate vaccine (TCV) in Nepalese children.
This randomized controlled trial assessed the persistence of immune responses to a single dose of typhoid conjugate vaccine (TCV) in 20,019 Nepalese children over five years.
Diagnostic accuracy of the VISITECT CD4 lateral-flow assay for screening advanced HIV disease: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed the diagnostic accuracy of the VISITECT-CD4 lateral-flow assay for advanced HIV disease, using flow cytometry as the comparator.
Acceptability of alcohol-based hand rub during neonatal care in rural Ugandan households: a qualitative study nested within the BabyGel trial.
This qualitative study, nested within the BabyGel trial, assessed the acceptability of an alcohol-based hand rub intervention among mothers and household members in rural Uganda.
Loss of blood pressure control after rifampin initiation: a clinically significant antihypertensive drug-drug interaction.
A man in his early 60s with well-controlled hypertension experienced a sudden increase in blood pressure two weeks after starting isoniazid-rifampin therapy for latent tuberculosis.
Endobronchial tuberculosis revealing extensive multiorgan dissemination in a severely malnourished immunocompetent adult.
A woman in her mid-30s presented with a 3-month history of dry cough, significant weight loss, and anorexia. She was diagnosed with pulmonary tuberculosis confirmed by bronchoalveolar lavage and endobronchial biopsy…
Emphysematous pyelonephritis-related delayed abdominal wall necrotizing fasciitis: A case report.
A 55-year-old woman with poorly controlled type II diabetes presented with emphysematous pyelonephritis (EPN) and required drainage.
Safety and pharmacokinetics of CL-197, a potent compound with low cytotoxicity against HIV-1: a randomized, double-blind, placebo-controlled, first-in-human phase 1 clinical trial.
This single-centre, randomized, double-blind, placebo-controlled, dose-escalation phase 1 trial assessed safety, tolerability and pharmacokinetics of single-dose CL-197 in healthy adults aged 18–45 years.
Spatiotemporal analysis of influenza, pneumonia, and respiratory syncytial virus in association with environmental factors: A systematic review.
This systematic review assessed studies using spatiotemporal models to examine environmental factors associated with influenza, pneumonia, and respiratory syncytial virus. Twelve studies met the inclusion criteria.
Spatio-temporal trends of the prevalence of Plasmodium falciparum antimalarial drug resistance markers across sub-Saharan Africa from 2010 to 2024: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the prevalence of Plasmodium falciparum antimalarial drug resistance markers across sub-Saharan Africa from 2010 to 2024.
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