Trending archive
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323 articles
May 20268
Atypical Spitz Tumor With RET::MXT1 Gene Rearrangement in a 14-Year-Old Girl: An Integrated Histopathologic, Immunohistochemical, and Molecular Diagnostic Approach.
A 14-year-old girl presented with a changing pigmented lesion on her upper back. Histopathological analysis revealed an asymmetric melanocytic proliferation with epithelioid cells and limited mitotic activity.
Myxoid Dermatofibrosarcoma Protuberans With Giant Cell Fibroblastoma Features in an Adult: Case Report and Review.
A 32-year-old man presented with a myxoid dermatofibrosarcoma protuberans (DFSP) that exhibited features of giant cell fibroblastoma.
Progressive alopecia areata during TNF-α inhibition with intralesional corticosteroid failure and subsequent improvement following JAK1 inhibition.
A 55-year-old woman with seropositive rheumatoid arthritis developed progressive alopecia areata while being treated with golimumab and leflunomide.
Efficacy and safety of ruxolitinib cream in patients with lichen sclerosus: Results from a phase 2, randomized, double-blind, vehicle-controlled study.
This phase 2 randomized controlled trial evaluated the efficacy and safety of 1.5% ruxolitinib cream in 61 adult women with anogenital lichen sclerosus.
Comparative efficacy and safety of oral azithromycin versus doxycycline in moderate-to-severe Acne vulgaris: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of oral azithromycin versus doxycycline in 2,769 patients with moderate to severe acne vulgaris.
Oral sarcoidosis: A systematic review of dental implications.
This systematic review examined oral sarcoidosis, a rare manifestation of a multisystem granulomatous disease, focusing on its clinical presentations and dental implications.
A safety checklist before initiating second-generation immunomodulating drugs for inflammatory dermatoses: a systematic review.
This systematic review examined contraindications and warnings for second-generation immunomodulating drugs used in inflammatory dermatoses.
Clinical progression of a smallpox postvaccination response.
A 20-year-old man with no significant medical history presented with a shallow, well-circumscribed, non-necrotic ulcer on his shoulder.
April 202616
Tranexamic acid protects human dermal fibroblasts from D-galactose-induced senescence via the GPR30/MAPK pathway.
This randomized controlled trial evaluated the effects of topical 3% tranexamic acid (TXA) on periorbital wrinkles in 50 women with facial melasma over 12 weeks.
Efficacy of polyphenolic compounds for hair regeneration: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis assessed the efficacy of polyphenolic compounds for hair regeneration in adults with non-scarring alopecia, analyzing 32 randomized controlled trials with 2,183 participants.
FDG Uptake in WT1 Peptide Vaccination Adjuvant-induced Granuloma: A 93-month Follow-up.
A woman in her 20s with alveolar rhabdomyosarcoma received WT1 peptide vaccination as part of an investigational immunotherapy.
Rheumatoid-type hand deformities in psoriatic arthritis: An illustrative case.
A 65-year-old female with a history of psoriasis presented with inflammatory hand pain and exhibited swan neck and Boutonniere deformities, along with tenderness in the distal interphalangeal joints and hallux varum.
Multicentric Reticulohistiocytosis Induced Alopecia: A Clinical Case Report.
A 52-year-old female presented with red-brown papules, finger swelling, and muscle pain. Biopsy confirmed multicentric reticulohistiocytosis (MRH) with characteristic histiocyte proliferation.
Hydrogen peroxide 40% versus trichloroacetic acid 70% in the treatment of seborrheic keratosis.
This randomized controlled trial compared the efficacy and safety of hydrogen peroxide 40% (H2O2) and trichloroacetic acid 70% (TCA) in treating seborrheic keratosis in 64 patients.
Intralesional secukinumab for localized, recalcitrant hidradenitis suppurativa: a case series of rapid symptom relief.
This case series evaluated the use of intralesional secukinumab in five patients with localized, recalcitrant hidradenitis suppurativa (HS) who had not responded to conventional therapies.
Comparative efficacy and safety of platelet-rich plasma (PRP), injectable platelet-rich fibrin (i-PRF) and concentrated growth factors (CGF) for female pattern hair loss (FPHL): a prospective multicenter randomized clinical trial.
This multicenter randomized controlled trial evaluated the efficacy and safety of platelet-rich plasma (PRP), injectable platelet-rich fibrin (i-PRF), and concentrated growth factors (CGF) in treating female pattern…
Modulation of mu-opioid pathway for the treatment of pruritus: a systematic review of 1,146 patients.
This systematic review analyzed the efficacy and safety of μ-opioid pathway modulators for treating pruritus in 1,146 patients across various dermatologic and systemic conditions.
Ultrasound Characterization of Spiradenoma: Case Report and Literature Review.
A spiradenoma was identified in a patient presenting with a cutaneous lesion that resembled an epidermoid cyst. Ultrasound imaging revealed a well-defined, multilobulated, heterogeneous, hypoechoic mass in the dermis…
Xanthomatous Reactions in Cutaneous Lupus Erythematosus-More Than an Incidental Finding?
Cutaneous lupus erythematosus (CLE) is a well-known autoimmune disorder within dermatology. However, findings of lipid-laden macrophages and xanthomas in a subset of these cases are less understood and usually labeled…
Cutaneous Acral Presentation of Indolent Mantle Cell Lymphoma With Prominent Nail Involvement and Atypical Immunophenotype.
A 56-year-old healthy male presented with a 5-year history of painful, edematous plaques and nail dystrophy on his bilateral toes.
Subcision Versus Subcision With Suction for the Treatment of Atrophic Acne Scars: A Randomized, Split-Face Clinical Trial.
This randomized, split-face clinical trial evaluated the effectiveness of subcision alone versus subcision with suction in 27 patients with atrophic acne scars.
Diffuse CD30-Positive Cutaneous Infiltrate in a Clinically Suspected Hidradenitis Suppurativa Lesion: Histopathologic and Diagnostic Challenges.
A 38-year-old male presented with a lesion in the left axilla, initially diagnosed as hidradenitis suppurativa (HS) and unresponsive to antibiotics.
High- and Ultra-High-Frequency Ultrasound Identifies a Subclinical Link Between Suppurative Comedonal Nevus and Hidradenitis Suppurativa.
Suppurative nevus comedonicus (SNC) is a variant of nevus comedonicus in which the characteristic features coexist with recurrent inflammatory lesions that clinically resemble those of hidradenitis suppurativa (HS).
Adnexal necrobiotic xanthogranuloma presenting as a "kissing" eyelid lesion.
A 50-year-old man presented with a rare form of necrobiotic xanthogranuloma, characterized by a 'kissing' lesion on the upper and lower eyelids.
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