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441 articles

July 202616

Clinical ResearchNeurology

The role of organochlorine pesticides as environmental factors in Alzheimer's disease in human studies: A systematic review and meta-analysis.

This systematic review and meta-analysis investigated the association between organochlorine pesticide (OCP) exposure and Alzheimer's disease (AD) risk in humans.

J Alzheimers DisJul 7, 2026Read summary
Clinical ResearchGeriatrics

Cognitive Impairment and Postoperative Outcomes in Patients Undergoing Primary Total Hip Arthroplasty and Primary Total Knee Arthroplasty: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis evaluated the impact of preoperative cognitive impairment on postoperative outcomes in older adults undergoing primary total hip arthroplasty (THA) and total knee arthroplasty…

Ann Afr MedJul 7, 2026Read summary
Case ReportEmergency Medicine

Fatal tracheobronchial obstruction caused by a swallowed glove: a rare forensic case with postmortem CT-autopsy correlation.

An elderly male with advanced dementia was found unresponsive in a hospital bed. Despite resuscitation efforts, no airway obstruction was identified.

Leg Med (Tokyo)Jul 6, 2026Read case
Clinical ResearchGeriatrics

A Community-Based Health Literacy Intervention to Improve Health Literacy, Health Behavior Self-Efficacy, and Quality of Life Among Older Adults With Frailty: A Quasi-Experimental Study.

This quasi-experimental study evaluated a Wellness Motivation Theory–based health education program among adults aged 60 to 85 years with physical frailty in two communities in Huzhou, China.

J Gerontol NursJul 6, 2026Read summary
Case ReportEmergency Medicine

Unexplained hyperammonemia in the emergency department: Late-onset ornithine transcarbamylase deficiency in a 75-year-old man.

A 75-year-old man presented to the emergency department with acute confusion and vomiting, which progressed to coma. Initial tests showed unexplained hyperammonemia, peaking at 487 μmol/L.

Am J Emerg MedJul 6, 2026Read case
Clinical ResearchGeriatrics

Effects of nutritional interventions on biomarkers of cellular senescence in humans: A systematic review.

This systematic review evaluated the effects of nutritional interventions on biomarkers of cellular senescence in humans, analyzing 29 studies with 3811 participants.

Ageing Res RevJul 4, 2026Read summary
Clinical ResearchNeurology

Efficacy of non-invasive brain stimulation in Alzheimer's disease: An umbrella review of meta-analyses.

This umbrella review evaluates the efficacy of non-invasive brain stimulation (NIBS) in Alzheimer's disease, analyzing 42 publications with 5771 patients.

Neurosci Biobehav RevJul 3, 2026Read summary
Clinical ResearchGeriatrics

Differences in Circulating Inflammatory Markers in Older Adults With and Without Sarcopenia: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined inflammatory markers in older adults with and without sarcopenia. The analysis included 44 studies and found that individuals with sarcopenia had significantly higher…

J Am Med Dir AssocJul 3, 2026Read summary
Clinical ResearchGeriatrics

Effects of comprehensive oral care on nasogastric tube removal in long-term care residents with dysphagia: A multi-center randomized controlled trial.

This multicenter randomized controlled trial assessed the impact of comprehensive oral care (COC) on nasogastric (NG) tube removal in long-term care residents with dysphagia.

Arch Gerontol GeriatrJul 2, 2026Read summary
Clinical ResearchGeriatrics

Dose-response relationship between exercise interventions and quality of life in older adults with cancer: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of exercise interventions on quality of life in 2557 older adults with cancer.

J Geriatr OncolJul 2, 2026Read summary
Clinical ResearchNeurology

Gut microbiota alterations in Alzheimer's disease and mild cognitive impairment: A systematic review and meta-analysis.

This systematic review and meta-analysis examined gut microbiota differences in older adults with Alzheimer's disease (AD) and mild cognitive impairment (MCI) compared to cognitively normal (CN) controls.

J Alzheimers DisJul 2, 2026Read summary
Clinical ResearchGeriatrics

The Effects of 8-Week Traditional Aerobic Exercise and Exergaming on Dual-Task Performance and Prefrontal Cortex Activation in Older Adults.

This randomized controlled trial compared 8 weeks of exergaming with traditional aerobic exercise in 33 older adults (mean age 64.2 ± 5.5 years).

Med Sci Sports ExercJul 2, 2026Read summary
Clinical ResearchGeriatrics

Effectiveness of Auricular Acupressure in Improving Sleep Quality and Reducing Insomnia Severity in Middle-Aged and Older Women in Taiwan.

This randomized controlled trial assessed the effectiveness of auricular acupressure on sleep quality and insomnia severity in 88 middle-aged and older women in Taiwan.

ANS Adv Nurs SciJul 1, 2026Read summary
Clinical ResearchGeriatrics

Impact of simultaneous motor-cognitive training on motor capacities in older adults: A quasi-randomized parallel controlled trial.

This randomized controlled trial evaluated the effects of two types of simultaneous motor-cognitive training on motor capacities in 55 older adults over eight weeks.

Exp GerontolJul 1, 2026Read summary
Clinical ResearchGeriatrics

A prospective, randomized exploratory study: Association of preemptive analgesia combined with preoperative transnasal insulin therapy with reduced postoperative delirium in elderly patients undergoing lower extremity fracture surgery.

This prospective, randomized exploratory trial studied the effects of preoperative intranasal insulin combined with preemptive analgesia on postoperative delirium (POD) in 186 elderly patients undergoing lower extremity…

Gen Hosp PsychiatryJul 1, 2026Read summary
Clinical ResearchGeriatrics

Effectiveness of a structured caregiver support program for caregivers of people with Alzheimer's disease: A mixed methods study.

This randomized controlled trial evaluated the Structured Caregiver Support Program (SCSP) for informal caregivers of individuals with Alzheimer's disease.

Geriatr NursJul 1, 2026Read summary

June 20268

Clinical ResearchGeriatricsOpen access

Effectiveness of community-based physical activity models in improving quality of life among elderly: A systematic review.

This systematic review evaluated the effectiveness of community-based physical activity models on quality of life in older adults (≥60 years).

Aten PrimariaJun 30, 2026Read summary
Clinical ResearchPsychiatry

Brexpiprazole With Antidepressants for Agitation in Alzheimer's Dementia: Post Hoc Analysis.

This post hoc analysis of two Phase 3 randomized controlled trials evaluated the efficacy and safety of brexpiprazole for agitation in Alzheimer's dementia, both with and without concomitant antidepressants.

Am J Geriatr PsychiatryJun 30, 2026Read summary
Clinical ResearchGeriatrics

Rehabilitation strategies in post menopausal women: a systematic review and meta-analysis of randomized trials.

This systematic review and meta-analysis evaluated the effects of rehabilitation and exercise-based interventions on postmenopausal women.

Eur J Obstet Gynecol Reprod BiolJun 29, 2026Read summary
Clinical ResearchGeriatrics

Diet and Cognitive Function in Aging: An Individual Participant Data Meta-Analysis from 8 Cohorts in Europe and the United States.

This meta-analysis examined the relationship between dietary patterns and cognitive function in 17,368 participants from 8 cohorts in Europe and the US.

J NutrJun 29, 2026Read summary
Clinical ResearchGeriatrics

Effects of different intensities of aerobic exercise on intestinal permeability and inflammatory response in older adults: Randomized clinical trial.

This randomized clinical trial examined the effects of high-intensity versus low-intensity aerobic exercise on intestinal permeability and inflammatory responses in 29 older adults (≥60 years).

Exp GerontolJun 29, 2026Read summary
Clinical ResearchGeriatrics

Gut microbial signature for frailty discrimination: a metagenomic meta-analysis of 28 independent cohorts.

This meta-analysis examined gut microbial signatures associated with frailty in 955 individuals from 28 cohorts across 24 countries.

Exp GerontolJun 29, 2026Read summary
Clinical ResearchGeriatricsOpen access

Study protocol for FAXAge: a randomized, controlled clinical trial of fasting and exercise to slow aging in humans.

The FAXAge study is a randomized controlled trial investigating the effects of fasting and exercise on biological aging in 240 healthy adults aged 65 and older.

GeroscienceJun 29, 2026Read summary
Clinical ResearchGeriatricsOpen access

Personalized blood flow restriction training at variable occlusion pressures improves multisystem function in overweight and obese older women.

This randomized controlled trial examined the effects of 12-week low-intensity blood flow restriction (BFR) training at varying arterial occlusion pressures on physiological functions in 180 overweight and obese women…

Eur J Appl PhysiolJun 29, 2026Read summary

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