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785 articles

August 202624

Case ReportGastroenterologyOpen access

Gastric lipoma causing ball-valve syndrome successfully treated by endoscopic submucosal dissection.

A 52-year-old woman presented with postprandial epigastric discomfort and nausea. CT showed a low-attenuation mass extending from the gastric antrum to the duodenal bulb; endoscopy found a broad-based subepithelial…

Clin J GastroenterolAug 14, 2026Read case
Clinical ResearchGastroenterology

Cryoablation versus radiofrequency ablation for hepatocellular carcinoma: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness and safety of cryoablation (CA) versus radiofrequency ablation (RFA) in treating hepatocellular carcinoma (HCC).

Int J HyperthermiaAug 13, 2026Read summary
Clinical ResearchGastroenterology

Efficacy and safety of pantoprazole for stress-ulcer prophylaxis in critically ill patients: A systematic review and Meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the efficacy and safety of pantoprazole for stress-ulcer prophylaxis in critically ill patients, including both adults and children.

J Crit CareAug 13, 2026Read summary
Clinical ResearchEndocrinology

Food-derived extracellular vesicles as delivery platforms for medicine-food homology components in metabolic syndrome.

This systematic review examines the role of food-derived extracellular vesicles (FDEVs) as delivery systems for medicine-food homology components (MFHCs) in managing diet-induced obesity and metabolic syndrome.

Food Res IntAug 13, 2026Read summary
Clinical ResearchGastroenterology

Bridging in vitro buoyancy to clinical performance: A PBPK-driven analysis of once-daily Bepotastine gastro-retentive tablet in beagles and humans.

This randomized controlled trial evaluated a low-density gastro-retentive tablet of Bepotastine in beagles and humans. The study found that the tablet achieved 95.7% systemic exposure compared to a twice-daily…

J Control ReleaseAug 13, 2026Read summary
Clinical ResearchGastroenterology

Comparison of the outcomes of ileal pouch-anal anastomosis and ileorectal anastomosis for patients with familial adenomatous polyposis: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated outcomes of ileal pouch-anal anastomosis (IPAA) versus ileorectal anastomosis (IRA) in 4700 patients with familial adenomatous polyposis.

J Gastrointest SurgAug 13, 2026Read summary
Clinical ResearchGastroenterology

The Effect of a Repetitive Feeding Challenge With Carbohydrate Versus Fat on Markers of Gastrointestinal Integrity and Systemic Outcomes in Response to Endurance Exercise.

This randomized controlled trial examined whether a 7-day repetitive feeding challenge with fat, compared with carbohydrate (CHO), affected gastrointestinal integrity and systemic inflammatory markers during endurance…

Int J Sport Nutr Exerc MetabAug 13, 2026Read summary
Clinical ResearchOncology (Medical)

Matching-adjusted indirect comparison of fruquintinib versus ramucirumab in advanced gastric or gastroesophageal junction adenocarcinoma.

This study conducted a matching-adjusted indirect comparison of fruquintinib plus paclitaxel versus ramucirumab plus paclitaxel in patients with advanced gastric or gastroesophageal junction adenocarcinoma.

J Comp Eff ResAug 12, 2026Read summary
Clinical ResearchEndocrinology

Efficacy and safety of once-weekly semaglutide 2·4 mg in Chinese adults with overweight or obesity (STEP 12): a randomised, double-blind, placebo-controlled, multicentre, phase 3b trial.

This phase 3b randomized, double-blind, placebo-controlled trial evaluated the efficacy and safety of once-weekly semaglutide 2.4 mg in Chinese adults with overweight or obesity.

Lancet Diabetes EndocrinolAug 10, 2026Read summary
Clinical ResearchGastroenterology

Meta-Analysis: Prevalence of Non-Helicobacter pylori, Non-NSAID Peptic Ulcer Disease.

This meta-analysis examined the prevalence of non-H. pylori, non-NSAID peptic ulcer disease (PUD) in adults, analyzing 92 studies with 60,816 patients. The findings revealed that 13.0% of overall PUD cases were non-H.

Aliment Pharmacol TherAug 10, 2026Read summary
Clinical ResearchEndocrinology

High-animal protein and high-plant protein meals differentially alter postprandial plasma amino acid concentrations but not glucose homeostasis in people with overweight/obesity in a randomized, crossover, single-meal study.

This randomized crossover trial examined the effects of high-animal protein (HAP) and high-plant protein (HPP) meals on postprandial plasma amino acid and glucose levels in individuals with overweight/obesity.

Am J Clin NutrAug 10, 2026Read summary
Clinical ResearchGastroenterology

Small intestinal compared with colonic short-chain fatty acid delivery drives distinct systemic concentrations and endocrine responses in humans: a randomized, crossover trial.

This randomized, crossover trial investigated the effects of short-chain fatty acid (SCFA) delivery to the small intestine versus the colon in 28 healthy adults.

Am J Clin NutrAug 10, 2026Read summary
Clinical ResearchOncology (Medical)

Inflammation hinders anabolic potential of nutritional support in cancer: findings from the Protein Recommendation to Increase Muscle (PRIMe) trial.

The PRIMe trial analyzed the impact of baseline inflammation on the effectiveness of high-protein nutritional support in patients with stage II-IV colorectal cancer.

Am J Clin NutrAug 10, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Comparison of Keverprazan-based versus esomeprazole-based dual therapy for initial treatment of Helicobacter pylori infection: a prospective, multicenter, randomized controlled trial.

This multicenter, randomized controlled trial compared 14-day keverprazan-amoxicillin therapy (KA) with esomeprazole-amoxicillin therapy (EA) in 264 treatment-naive adults with Helicobacter pylori infection.

Ann MedAug 9, 2026Read summary
Clinical ResearchGastroenterology

Systematic Review and Meta-Analysis: Plant-Based Therapy for Irritable Bowel Syndrome.

This systematic review and meta-analysis evaluated the efficacy and safety of plant-based therapies for irritable bowel syndrome (IBS) in 6329 patients across 60 studies.

Phytother ResAug 9, 2026Read summary
Case ReportGastroenterologyOpen access

Portal vein invasion and cavernous transformation secondary to hepatic echinococcosis successfully managed by TIPS: a case report and literature review.

A 44-year-old woman with recurrent gastrointestinal bleeding had a history of right hepatectomy for hepatic alveolar echinococcosis.

Clin J GastroenterolAug 8, 2026Read case
Clinical ResearchGastroenterologyOpen access

Diagnostic and Clinical Performance of Single-Use Versus Reusable Gastrointestinal Endoscopes: A Systematic Review and Meta-Analyses.

This systematic review and meta-analysis evaluated the diagnostic and clinical performance of single-use versus reusable gastrointestinal endoscopes across 50 studies involving 965,960 patients.

J Gastroenterol HepatolAug 7, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Artificial Intelligence-Assisted Liver Ultrasound Training: Image Recognition and Real-Time Feedback System Based on YOLO and DeepSeek.

This randomized controlled trial evaluated an AI-assisted liver ultrasound training system using the YOLOv11n algorithm and DeepSeek model among 20 students.

Acad RadiolAug 7, 2026Read summary
Case ReportPathology (Anatomic & Clinical)Open access

Multifocal primary hepatic epithelioid hemangioendothelioma: a case in which tumor biopsy was critical to prevent misdiagnosis.

An 82-year-old woman undergoing postoperative surveillance for bladder cancer was found to have multiple hepatic masses on contrast-enhanced CT.

Clin J GastroenterolAug 7, 2026Read case
Case ReportGastroenterologyOpen access

Acute-on-chronic liver failure following pneumonia in an elderly woman with metabolic dysfunction-associated steatotic liver cirrhosis.

A woman in her 80s with cirrhosis associated with metabolic dysfunction-associated steatotic liver disease developed prolonged acute-on-chronic liver failure (ACLF) triggered by pneumonia.

Clin J GastroenterolAug 7, 2026Read case
Clinical ResearchGastroenterology

Barriers and facilitators to formal mental health help-seeking in individuals living with inflammatory bowel disease: A systematic review.

This systematic review synthesised evidence on factors influencing formal mental health help-seeking among people living with inflammatory bowel disease (IBD).

J Psychosom ResAug 7, 2026Read summary
Clinical ResearchCardiology

From gut to heart: the emerging role of dietary fermentable fiber in heart failure with preserved ejection fraction.

This systematic review examines the role of dietary fermentable fiber (FF) and short-chain fatty acids (SCFAs) in heart failure with preserved ejection fraction (HFpEF).

Am J Physiol Heart Circ PhysiolAug 6, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Assessing Graded Histological Regression as Basis for Treatment Modification after Neoadjuvant Therapy in LAGC: An Exploratory Phase II Study.

This prospective, single-centre, open-label, randomised phase II trial assessed whether graded histologic regression (GHR) below 50% could guide adjuvant chemotherapy modification in locally advanced gastric cancer…

Ann Surg OncolAug 6, 2026Read summary
Clinical ResearchGeneral Surgery

A two-center randomized clinical superiority trial of single-anastomosis sleeve ileal bypass versus sleeve gastrectomy for severe obesity: SASSY study protocol.

The SASSY study is a two-center randomized clinical trial comparing single-anastomosis sleeve ileal bypass to sleeve gastrectomy in patients with class II and III obesity.

Scand J SurgAug 5, 2026Read summary

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