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785 articles
July 202624
Systematic Review: Evaluating the Prognostic Value of Granulomas in Crohn's Disease.
This systematic review evaluated the prognostic value of granulomas in Crohn's disease (CD) by analyzing 46 studies, including 37 cohort analyses.
Optimal dose window, formulation efficacy, and molecular mechanisms of curcumin in MASLD animal models: A systematic review and three-level meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of curcumin in animal models of metabolic dysfunction-associated steatotic liver disease (MASLD).
Peripheral parenteral nutrition improves short-term nutritional status and inflammatory reaction after colorectal resection surgery: A randomized clinical trial.
This randomized controlled trial evaluated the effects of early postoperative peripheral parenteral nutrition (PPN) on nutritional status and inflammatory response in 207 patients after colorectal resection.
Feasibility, Acceptability, and Preliminary Effects of a Nurse-Delivered Self-Management Program for Individuals with Inflammatory Bowel Disease: A Pilot Randomized Controlled Trial.
This pilot randomized controlled trial evaluated a nurse-delivered self-management program for adults with inflammatory bowel disease, focusing on feasibility, acceptability, and preliminary effects.
Efficacy and Safety of Statins in Patients with Liver Cirrhosis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials with Trial Sequential Analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of statins in patients with liver cirrhosis, analyzing data from thirteen randomized controlled trials.
Clinical and Metabolic Effects of Preoperative Carbohydrate Loading Before Colorectal Surgery: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the effects of preoperative carbohydrate loading in 1387 patients undergoing colorectal surgery.
Imported cystic echinococcosis caused by Echinococcus granulosus sensu stricto genotype G3 in Japan.
A Japanese man in his 50s, with a history of living in high-altitude rural areas, presented with abdominal distension. Imaging revealed a 15-cm cystic lesion in the left hepatic lobe, consistent with cystic…
Anticancer, hepatoprotective, and mechanistic evidence of chlorogenic acid in liver cancer: A systematic review.
This systematic review evaluated the effects of chlorogenic acid (CGA) on liver cancer, analyzing 21 studies. CGA showed anticancer effects in preclinical models by inhibiting tumor cell proliferation and inducing…
Long-term clinical trajectory of microvillus inclusion disease associated with STXBP2-related familial hemophagocytic lymphohistiocytosis type 5: A case report.
A 22-year-old male with familial hemophagocytic lymphohistiocytosis type 5 presented with chronic diarrhea that began in infancy and persisted despite bone marrow transplantation.
A rare case of a ciliated hepatic foregut cyst with progressive enlargement causing obstructive jaundice.
A 73-year-old woman presented with anorexia and obstructive jaundice. Imaging showed a 40-mm unilocular cyst in hepatic segment 4, first identified 10 years earlier but enlarged over the preceding 5 months.
A case of a pancreatic pseudocyst associated with alcoholic chronic pancreatitis that mimicked a mucinous cystic neoplasm.
A 64-year-old woman with alcoholic liver cirrhosis had a progressively enlarging cyst in the pancreatic body and elevated serum carbohydrate antigen 19-9.
Artificial intelligence-assisted detection and optical differentiation of colorectal lesions in Lynch syndrome surveillance (CADLY2): a multicentre, open-label, randomised controlled superiority trial.
The CADLY2 trial evaluated the impact of computer-aided detection (CADe) on adenoma detection rates during surveillance colonoscopy in patients with Lynch syndrome.
Increased Activity of the Pancreatic Infarcts Mimicking Malignancy on FDG PET/CT.
A patient developed multiple iatrogenic pancreatic infarcts following transcatheter bronchial artery embolization for hemoptysis due to lung cancer.
Efficacy and safety of duvakitug in patients with ulcerative colitis (RELIEVE UCCD): a phase 2b, randomised, placebo-controlled trial.
This phase 2b, multicenter, randomized, placebo-controlled trial evaluated the efficacy and safety of duvakitug in adults with moderately to severely active ulcerative colitis.
Efficacy and safety of duvakitug in patients with Crohn's disease (RELIEVE UCCD): a phase 2b, randomised, placebo-controlled trial.
This phase 2b, randomized, placebo-controlled trial evaluated the efficacy and safety of duvakitug in adults with moderately to severely active Crohn's disease.
Comparison of long-term outcomes between liver transplantation and liver resection for intrahepatic cholangiocarcinoma: An updated systematic review and meta-analysis.
This systematic review and meta-analysis evaluated long-term outcomes of liver transplantation (LT) versus liver resection (LR) for intrahepatic cholangiocarcinoma (ICC) in 5478 patients.
Comparative diagnostic performance of ultrasound and magnetic resonance imaging for predicting microvascular invasion in hepatocellular carcinoma: a head-to-head meta-analysis.
This meta-analysis evaluated the diagnostic performance of ultrasound (US) and magnetic resonance imaging (MRI) for predicting microvascular invasion (MVI) in hepatocellular carcinoma (HCC) across five studies involving…
Corticosteroids in severe alcohol-related hepatitis: A multicenter randomized clinical trial.
This multicenter randomized controlled trial evaluated the effect of corticosteroid therapy on survival in patients with severe alcohol-related hepatitis (AH) showing early spontaneous bilirubin improvement.
Acute liver injury and facial edema following ingestion of mushroom Descolea quercina.
In September 2025, a fresh wild mushroom poisoning incident involving five individuals occurred in Sichuan Province, China, three of whom developed poisoning symptoms.
Efficacy and safety of zalfermin co-administered with semaglutide in participants with fibrosis and cirrhosis due to metabolic dysfunction-associated steatohepatitis: a phase 2, dose-ranging, double-blind, randomised controlled trial.
This phase 2, double-blind, randomised controlled trial assessed the efficacy and safety of zalfermin co-administered with semaglutide in patients with metabolic dysfunction-associated steatohepatitis and fibrosis or…
Transcutaneous auricular vagus nerve stimulation for prevention of postoperative cognitive dysfunction in older adults with gastrointestinal tumors: A randomized controlled trial.
This randomized controlled trial investigated the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on postoperative cognitive dysfunction (POCD) in 103 older adults undergoing laparoscopic…
Diagnostic Accuracy of Optical Endoscopic Evaluation and EUS for Differentiating T1a and T1b Barrett's Adenocarcinoma: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the diagnostic accuracy of optical endoscopic evaluation (OEE) and endoscopic ultrasound (EUS) in differentiating T1a from T1b Barrett's adenocarcinoma in 2,292…
Outcomes of nucleos(t)ide analogue discontinuation following finite xalnesiran-based therapies in chronic hepatitis B.
This phase II randomized controlled trial evaluated the outcomes of nucleos(t)ide analogue (NA) discontinuation in 121 virologically suppressed participants with chronic hepatitis B (CHB) following xalnesiran-based…
HER2-positive rectal adenocarcinoma metastatic to the pancreas complicated by obstructive pancreatitis and an infected pseudocyst: a case report.
A man in his 60s presented with cerebellar masses; PET-CT also showed hypermetabolic lesions in the rectum and pancreas. Testing identified HER2-positive, RAS/BRAF wild-type rectal adenocarcinoma.
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