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186 articles

October 20268

Clinical ResearchGastroenterology

Advanced therapies for extraintestinal manifestations of IBD: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the efficacy of advanced therapies (ATs) for extraintestinal manifestations (EIMs) in patients with inflammatory bowel diseases (IBD).

Inflamm Bowel DisOct 1, 2026Read summary
Clinical ResearchDermatology

Long-Term Safety and Efficacy of Dazukibart in Dermatomyositis: Combined Phase II Results From Double-Blind and Open-Label Extension Studies.

This study evaluated the long-term safety and efficacy of dazukibart, an antiinterferon β monoclonal antibody, in adults with moderate-to-severe dermatomyositis through a combined Phase II randomized controlled trial…

J RheumatolOct 1, 2026Read summary
Clinical ResearchRheumatology

Bimekizumab Long-Term Safety and Efficacy Across the Spectrum of Axial Spondyloarthritis Over 3 Years: Results From 2 Phase III Studies.

This study evaluated the long-term safety and efficacy of bimekizumab, an IL-17A and IL-17F inhibitor, in patients with axial spondyloarthritis over 3 years.

J RheumatolOct 1, 2026Read summary
Clinical ResearchRheumatology

Follow-Up 18F-Fluorodeoxyglucose Positron Emission Tomography in Treated Patients With Giant Cell Arteritis: A Systematic Review and Metaanalysis.

This systematic review and meta-analysis evaluated the use of 18F-fluorodeoxyglucose (FDG) PET to monitor disease activity in patients with large-vessel giant cell arteritis (LV-GCA) who showed clinical improvement…

J RheumatolOct 1, 2026Read summary
Clinical ResearchRheumatology

Effects of Yoga on Rheumatoid Arthritis: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the effects of yoga on psychological function and inflammation in individuals with rheumatoid arthritis (RA).

Int J Rheum DisOct 1, 2026Read summary
Clinical ResearchRheumatology

Temporal Patterns of Outcomes After DMARD Tapering or Withdrawal in Rheumatoid Arthritis With Sustained Disease Control: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the effects of DMARD tapering and withdrawal in patients with rheumatoid arthritis (RA) who had sustained disease control.

Clin Transl SciOct 1, 2026Read summary
Clinical ResearchRheumatology

First-line biologic and targeted synthetic DMARDs versus methotrexate in early rheumatoid arthritis: a meta-analysis of remission outcomes.

This systematic review and meta-analysis of randomized trials compared initial biologic and targeted synthetic DMARDs (b/tsDMARDs), alone or with methotrexate, against methotrexate in methotrexate-naïve adults with…

Rheumatology (Oxford)Oct 1, 2026Read summary
Clinical ResearchRheumatology

Bimekizumab efficacy in male and female patients with axial spondyloarthritis: 52-week results from the phase 3 BE MOBILE trials.

This post hoc analysis of two phase 3 randomised trials assessed sex-based differences in bimekizumab response among patients with radiographic or non-radiographic axial spondyloarthritis.

Rheumatology (Oxford)Oct 1, 2026Read summary

September 202616

Case ReportDermatology

Metastatic melanoma presenting with paraneoplastic dermatomyositis mimicking polymyalgia rheumatica.

A man in his late 70s presented with bilateral shoulder and hip girdle pain, morning stiffness, and significant weight loss over six weeks.

BMJ Case RepSep 30, 2026Read case
Clinical ResearchRheumatology

Anakinra versus intramuscular methylprednisolone acetate for gout flares in people with chronic kidney disease (ASGARD): a UK randomised multicentre, double-blind, double-dummy controlled feasibility study with economic, qualitative and safety assessment.

The ASGARD study was a feasibility randomized controlled trial comparing anakinra to intramuscular methylprednisolone acetate for treating gout flares in patients with chronic kidney disease.

BMJ OpenSep 30, 2026Read summary
Clinical ResearchRheumatologyOpen access

Lower HLA-B27 positivity and heterogeneous late-onset case proportions across axial spondyloarthritis cohorts: a systematic review and meta-analysis.

This systematic review and meta-analysis examined late-onset ankylosing spondylitis (AS) and axial spondyloarthritis (axSpA) in clinical cohorts, focusing on cases with onset at or after age 45.

Rheumatol IntSep 30, 2026Read summary
Clinical ResearchMedical Genetics

Efficacy and safety of garetosmab, an activin A-blocking antibody, in fibrodysplasia ossificans progressiva (OPTIMA): a randomised, double-blind, placebo-controlled, phase 3 trial.

OPTIMA was a multicentre, randomised, double-blind, placebo-controlled phase 3 trial assessing monthly intravenous garetosmab in adults with fibrodysplasia ossificans progressiva.

LancetSep 28, 2026Read summary
Clinical ResearchNeurology

Prevalence of autoimmune comorbidities in aquaporin 4-immunoglobulin G positive neuromyelitis optica spectrum disorder: a systematic review and meta-analysis.

This systematic review and meta-analysis estimated the prevalence of autoimmune comorbidities among people with aquaporin-4-immunoglobulin G-positive neuromyelitis optica spectrum disorder.

Mult Scler Relat DisordSep 28, 2026Read summary
Clinical ResearchPediatrics

Turning distress into distraction: using virtual reality during penicillin injections for rheumatic fever.

This phase IIA clinical trial evaluated the use of immersive virtual reality (VR) during subcutaneous penicillin injections in 10 participants aged 9-20 years with acute rheumatic fever.

N Z Med JSep 25, 2026Read summary
Case ReportRheumatology

Takayasu arteritis manifesting as pyrexia of unknown origin and massive splenomegaly.

A male patient in his early 20s presented with a three-month history of pyrexia of unknown origin, significant weight loss, a left carotid bruit, and massive splenomegaly.

BMJ Case RepSep 24, 2026Read case
Case ReportRheumatology

Drug-Induced Liver Injury During Treatment With Tocilizumab: A Case Report of an Atypical Pattern Lesion.

A 75-year-old patient with giant cell arteritis developed jaundice and abdominal pain after the third infusion of tocilizumab.

Pharmacol Res PerspectSep 23, 2026Read case
Clinical ResearchRheumatology

Patient experiences with digital health interventions in self-management of rheumatic and musculoskeletal diseases: a systematic review and qualitative meta-synthesis.

This systematic review and qualitative meta-synthesis examined patient experiences with digital health interventions (DHIs) for self-management in rheumatic and musculoskeletal diseases (RMDs).

BMJ OpenSep 23, 2026Read summary
Case ReportRheumatologyOpen access

Male Systemic Lupus Erythematosus: A Rare Case of Multisystem Involvement.

A 31-year-old man with systemic lupus erythematosus presented with fatigue, joint pain, fever, and a photosensitive rash. Laboratory tests revealed positive antinuclear antibodies and elevated anti-double-stranded DNA…

Int Med Case Rep JSep 23, 2026Read case
Clinical ResearchGeriatrics

Systematic review of cost-effectiveness analyses of weight loss interventions for knee osteoarthritis.

This systematic review assessed the cost-effectiveness of weight-loss interventions for adults with knee osteoarthritis and obesity.

BMJ OpenSep 22, 2026Read summary
Case ReportNeurology

Scalp necrosis and visual loss in giant cell arteritis: the importance of recognising atypical cutaneous clues.

A 70-year-old woman presented with left hemifacial pain and bilateral forehead skin plaques, initially diagnosed as shingles.

Pract NeurolSep 20, 2026Read case
Case ReportRheumatologyOpen access

Non-Radiographic Axial Spondyloarthritis Presenting with Anterior Chest Wall Pain without Inflammatory Back Pain in an HLA-B27-Negative Young Man: A Case Report Highlighting Diagnostic Challenges.

A 22-year-old HLA-B27-negative male presented with mild anterior chest wall pain, initially deemed mechanical and treated with NSAIDs.

Int Med Case Rep JSep 19, 2026Read case
Case ReportGastroenterology

Septic arthritis mimic unmasked: inflammatory bowel disease-associated arthritis in a patient with a learning disability.

A man in his early 30s with a mild learning disability presented with acute left-knee pain, swelling, erythema, and fevers, alongside low-back and hip pain.

BMJ Case RepSep 18, 2026Read case
Clinical ResearchGeriatricsOpen access

Associations Between Peripheral Blood Inflammatory and Immune Markers and Osteoporotic and Fragility Fractures: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the associations between peripheral blood inflammatory and immune markers and osteoporotic or fragility fractures.

Calcif Tissue IntSep 18, 2026Read summary
Clinical ResearchRheumatology

High potency and water dispersible Boswellia extract reduces pain and inflammation in subjects with osteoarthritis of the knee: A randomized, double-blind, placebo-controlled trial.

This randomized, double-blind, placebo-controlled trial evaluated the effects of a high potency Boswellia extract (OLNP-27) on knee osteoarthritis in 60 subjects aged 40 to 75.

Medicine (Baltimore)Sep 18, 2026Read summary

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