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1316 articles

October 202624

Clinical ResearchCardiologyOpen access

Complexity of coronary artery disease in infarct-related cardiogenic shock and multivessel disease: a substudy of the DanGer Shock trial.

This study, a secondary analysis of the DanGer Shock trial, evaluated the prognostic significance of baseline and residual SYNTAX scores in 256 patients with multivessel disease and infarct-related cardiogenic shock.

EuroInterventionOct 5, 2026Read summary
Clinical ResearchPsychiatry

Systematic review and meta-analysis: the effectiveness of cognitive behavioral therapy and eye movement desensitization and reprocessing in children and adolescents.

This systematic review and meta-analysis evaluated the effectiveness of cognitive behavioral therapy (CBT) versus eye movement desensitization and reprocessing (EMDR) for treating PTSD in children and adolescents aged…

Eur J PsychotraumatolOct 5, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Morphometric findings of the subaxial cervical spine among different geographic regions and the implications for cervical pedicle screw placement: a systematic review and meta-analysis.

This systematic review and meta-analysis examined cervical pedicle dimensions and insertion angles across diverse populations, analyzing data from 4014 patients across 18 countries.

Neurosurg RevOct 5, 2026Read summary
Clinical ResearchNeurology

Bilateral gamma knife radiosurgery in severe essential tremor: a prospective trial.

This phase II prospective trial evaluated the safety and efficacy of staged bilateral Gamma Knife radiosurgery (GKS) of the ventral intermedius thalamic nucleus in 33 patients with severe essential tremor.

BrainOct 5, 2026Read summary
Clinical ResearchGastroenterology

SYSTEMATIC REVIEW AND BRAZILIAN EXPERT CONSENSUS ON THE USE OF BIOSIMILARS IN INFLAMMATORY BOWEL DISEASE: BRAZILIAN ORGANIZATION FOR CROHN'S AND COLITIS.

This systematic review and Brazilian expert consensus assessed biosimilar use in inflammatory bowel disease (IBD), addressing clinical, therapeutic, and economic questions.

Arq GastroenterolOct 5, 2026Read summary
Clinical ResearchOphthalmology

Microperimetry Sensitivity Changes at the Functional Transition Zone and at the EZ Margins in X-Linked Retinitis Pigmentosa Treated With Gene Therapy.

This post-hoc analysis of the randomized Skyline trial examined how photoreceptor ellipsoid-zone (EZ) structure related to microperimetry sensitivity in eyes with X-linked retinitis pigmentosa treated with gene therapy.

Transl Vis Sci TechnolOct 5, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Adjunctive neuromuscular electrical stimulation and cognitive-motor interference during gait in older inpatients.

This exploratory analysis of a pragmatic pilot trial examined whether adjunctive neuromuscular electrical stimulation (NMES) was associated with changes in cognitive-motor interference during gait among older inpatients…

Exp GerontolOct 5, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

The utility of magnetic resonance imaging of the spinal cord in paediatric transverse myelitis: A systematic review.

This systematic review assessed spinal cord MRI findings, agreement with CSF inflammation, and prognostic associations in children with monophasic acute transverse myelitis.

Mult Scler Relat DisordOct 5, 2026Read summary
Clinical ResearchGeneral Surgery

Restorative resection in robot-assisted versus laparoscopic total mesorectal excision: systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the outcomes of robot-assisted total mesorectal excision (R-TME) versus laparoscopic total mesorectal excision (L-TME) in rectal cancer surgery, involving 7133 patients…

Br J SurgOct 5, 2026Read summary
Clinical ResearchPsychiatry

Dynamic change patterns in suicidal ideation differ in Brief Cognitive Behavioral Therapy (BCBT) and Present-Centered Therapy (PCT).

This randomized clinical trial examined how five dimensions of suicidal ideation changed during Brief Cognitive Behavioral Therapy (BCBT) versus Present-Centered Therapy (PCT) among high-risk U.S.

Behav Res TherOct 5, 2026Read summary
Clinical ResearchAnesthesiology

Repeated remimazolam sedation for interstitial brachytherapy in cervical cancer: a randomized controlled trial.

This randomized controlled trial evaluated the safety and efficacy of repeated remimazolam sedation compared to propofol in 100 patients with cervical cancer undergoing interstitial brachytherapy.

Ann MedOct 4, 2026Read summary
Clinical ResearchHematologyOpen access

Interference of iron deficiency in glycated hemoglobin testing and its clinical implications: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of iron deficiency anemia (IDA) and latent iron deficiency (LID) on glycated hemoglobin (HbA1c) concentrations.

Biochem Med (Zagreb)Oct 4, 2026Read summary
Clinical ResearchHematologyOpen access

N-acetylcysteine mouthwash for prevention of oral mucositis in hematopoietic cell transplant recipients: a double-blind randomized controlled trial.

This double-blind randomized controlled trial evaluated the efficacy of N-acetylcysteine (NAC) mouthwash in preventing oral mucositis (OM) in 106 hematopoietic cell transplant (HCT) recipients.

Support Care CancerOct 4, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Effects of exercise and educational programs on long-term quality of life, anxiety, and depression in breast cancer survivors: an exploratory secondary analysis of the Setouchi breast project-10 randomized controlled trial.

This exploratory secondary analysis of a randomized controlled trial examined exercise and education for 342 patients with stage 0–III breast cancer within one year of completing treatment.

Breast CancerOct 3, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Determinants of delayed antenatal visit attendance in rural Burkina Faso: a cross-sectional study.

This cross-sectional study assessed delayed antenatal care (ANC) attendance among pregnant women in rural Burkina Faso. Out of 2480 women with data, 90.6% attended their first ANC visit after the 14th week of gestation.

BMC Pregnancy ChildbirthOct 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Continuous infusion of granulocyte colony-stimulating factor is associated with an advantage in neutrophil recovery in pediatric oncologic disorders.

This randomized controlled trial evaluated the effects of continuous infusion versus injection of granulocyte colony-stimulating factor (G-CSF) on neutrophil recovery in 20 pediatric oncology patients.

Cancer Chemother PharmacolOct 3, 2026Read summary
Clinical ResearchPathology (Anatomic & Clinical)

Concordance of Microbiological and Histopathological Examination of Bone Biopsies in Diagnosing Diabetic Foot Osteomyelitis, a Systematic Review.

This systematic review evaluated the diagnostic concordance of histopathology and microbiology in bone biopsies from 308 adults with diabetic foot osteomyelitis (DFO).

J Foot Ankle ResOct 3, 2026Read summary
Clinical ResearchGeriatrics

Vitamin D Supplementation and Mortality in the Elderly: A Review of a Meta-Analysis of Randomized Controlled Trials Using the REB Method.

This meta-analysis reviewed 25 randomized controlled trials (RCTs) to evaluate the impact of vitamin D supplementation on mortality in individuals aged 75 and older.

Fundam Clin PharmacolOct 3, 2026Read summary
Clinical ResearchOncology (Medical)

Trial-specific absolute disease-free survival effects of postoperative PD-1/PD-L1 blockade after complete resection of NSCLC: A systematic review.

This systematic review estimated absolute disease-free survival (DFS) effects of postoperative single-agent PD-1/PD-L1 blockade after complete resection of non-small-cell lung cancer.

Lung CancerOct 3, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Predictors and causes of 30-day failure after shunt placement in pediatric hydrocephalus: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated 30-day failure rates of ventriculoperitoneal (VP) shunts in pediatric hydrocephalus, analyzing data from 11,596 patients.

Childs Nerv SystOct 3, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Comparison of video-based and presentation-based self-directed instruction for learning basic neuroangiography.

This randomized controlled trial compared video-based and presentation-based self-directed instruction for teaching basic neuroangiography skills to 20 participants with varying prior experience.

BMC Med EducOct 3, 2026Read summary
Clinical ResearchGeriatricsOpen access

Should I drink water or wine? Impacts of online nutritional counseling on the alcohol consumption of elderly individuals with mild cognitive impairment : Secondary Data Analysis from the RCT "BrainFit-Nutrition".

This secondary data analysis from a randomized controlled trial evaluated the effects of nutritional counseling on alcohol consumption in 189 elderly individuals with mild cognitive impairment (MCI) over 12 months.

BMC Public HealthOct 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Prevalence of osteoporosis and low bone mass in men with prostate cancer: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the prevalence of osteoporosis and low bone mass in 91,913 men with prostate cancer (PCa).

Support Care CancerOct 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Boesenbergia rotunda extract-based mucoadhesive mouth gargle for chemoradiation-induced oral mucositis: A prospective randomized controlled study.

This randomized controlled trial evaluated the efficacy of a Boesenbergia rotunda extract-based mouth gargle in managing chemoradiation-induced oral mucositis in head and neck cancer patients.

Support Care CancerOct 3, 2026Read summary

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