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962 articles

May 202619

Clinical ResearchCardiology

CorCal Outcomes: A randomized trial using the pooled cohort equation or coronary artery calcium to select statin therapy in primary prevention patients. Study design and baseline characteristics.

The CorCal Outcomes trial is a randomized controlled trial comparing the effectiveness of coronary artery calcium (CAC) versus the pooled cohort equation (PCE) for guiding statin therapy in primary prevention patients.

Am Heart JMay 7, 2026Read summary
Clinical ResearchCardiologyOpen access

Cost-effectiveness of in-hospital motivational smoking cessation counselling and proactive referral to community-based follow-up.

This multicenter randomized controlled trial evaluated the cost-effectiveness of in-hospital motivational smoking cessation counselling with proactive community referral among hospitalized patients with atherosclerotic…

AddictionMay 7, 2026Read summary
Case ReportCardiologyOpen access

Asymptomatic Giant Right Ventricular Myxoma in an Adolescent: A Rare Case Report With Favorable Surgical Outcome.

A 13-year-old female presented with a giant right ventricular myxoma, measuring 70 × 35 × 49 mm, discovered during routine health screening.

J Clin UltrasoundMay 7, 2026Read case
Case ReportCardiology

Quantitative UHF-ECG Assessment of Pacing-Induced Ventricular Activation: Comparison of LBBAP and RV Septal Pacing.

This report describes two patients with bradycardia who underwent dual-chamber pacemaker implantation, one receiving left bundle branch area pacing (LBBAP) and the other right ventricular septal pacing (RVSP).

Pacing Clin ElectrophysiolMay 7, 2026Read case
Clinical ResearchCardiology

Serial assessment of NT-proBNP and high-sensitivity cardiac troponin with glucagon-like peptide-1 receptor agonist therapy in type 2 diabetes: Insights from EXSCEL.

This randomized controlled trial from the EXSCEL study evaluated the prognostic value of NT-proBNP and high-sensitivity cardiac troponin I in 4,292 adults with type 2 diabetes receiving exenatide or placebo.

Am Heart JMay 6, 2026Read summary
Case ReportObstetrics & Gynecology

Emergent simultaneous cesarean section and maternal cardiac surgery.

A 38-year-old woman at 37 weeks of pregnancy presented with severe dyspnea and hypertension. Echocardiography revealed a 4 cm myxoma in the left atrium causing significant left ventricular inflow obstruction.

Heart LungMay 6, 2026Read case
Case ReportCardiologyOpen access

When amyloid chooses sides: septal affection pattern as an atypical presentation of transthyretin amyloid cardiomyopathy.

A 73-year-old man with wild-type transthyretin amyloid cardiomyopathy had an atypical pattern of cardiac involvement on multimodality imaging.

Int J Cardiovasc ImagingMay 6, 2026Read case
Clinical ResearchEndocrinology

Semaglutide improves markers of cardiovascular risk in people with HIV.

This phase II clinical trial investigated the effects of semaglutide on cardiovascular risk markers in 36 adults with HIV and metabolic dysfunction.

AIDSMay 4, 2026Read summary
Case ReportMedical Genetics

Defining Features of Gabriele-de Vries Syndrome in Adults: A Case Report and Literature Review.

A 63-year-old woman with Gabriele-de Vries syndrome presented with mild intellectual disability, bilateral cataracts, and early-onset coronary artery disease.

Am J Med Genet AMay 4, 2026Read case
Clinical ResearchCardiologyOpen access

Identifying DASH Adherence Patterns and Their Association With Dietary Behaviors Among Adults With Hypertension.

This randomized controlled trial analyzed DASH diet adherence patterns among 301 adults with hypertension. The study identified three adherence subgroups: low (44.2%), high (41.2%), and mixed-pattern (14.6%).

Res Nurs HealthMay 4, 2026Read summary
Clinical ResearchCardiology

Randomized trial of tricuspid flexible band versus rigid ring in patients with moderate tricuspid regurgitation or greater: results of the JPH2019 trial.

This randomized controlled trial compared the efficacy of flexible band versus rigid ring annuloplasty in 321 patients with moderate or greater tricuspid regurgitation (TR).

J Thorac Cardiovasc SurgMay 4, 2026Read summary
Clinical ResearchCardiology

A prospective, multicenter trial of irrigated radiofrequency ablation and cryoablation to treat nonparoxysmal atrial fibrillation.

This prospective, multicenter clinical trial evaluated the efficacy and safety of irrigated radiofrequency (iRF) ablation and cryoablation for nonparoxysmal atrial fibrillation (NPAF) in patients undergoing cardiac…

J Thorac Cardiovasc SurgMay 4, 2026Read summary
Clinical ResearchCardiology

Effects of repeated periods of high-intensity interval training on myocardial function in patients with metabolic syndrome: A 16-month follow-up.

This randomized controlled trial investigated the effects of two periods of high-intensity interval training (HIIT) on myocardial function in 88 middle-aged patients with metabolic syndrome over 16 months.

J CardiolMay 4, 2026Read summary
Case ReportCardiologyOpen access

Cardiac POCUS in Undifferentiated Shock Revealing Aortic Dissection.

A 43-year-old man with Marfan syndrome and a history of ascending aortic replacement presented in shock after transfer to the ICU.

J Clin UltrasoundMay 4, 2026Read case
Clinical ResearchCardiologyOpen access

Extending Inferences from a Randomized Trial to Trial-eligible and Treatment-candidate Target Populations: Examples of Generalizability and Transportability.

This study extends findings from the VALIDATE-SWEDEHEART randomized trial, which compared bivalirudin and heparin during percutaneous coronary intervention, to broader populations.

EpidemiologyMay 4, 2026Read summary
Clinical ResearchNephrology

A meta-analysis of the hemodynamic and echocardiographic changes following arteriovenous fistula ligation in chronic kidney disease patients.

This meta-analysis evaluated the hemodynamic and echocardiographic effects of arteriovenous fistula (AVF) ligation in 844 patients with end-stage kidney disease.

J Vasc AccessMay 4, 2026Read summary
Clinical ResearchPulmonology

Effects of continuous positive airway pressure therapy on depression and anxiety in patients with obstructive sleep apnea with and without coronary heart disease.

This randomized controlled trial examined the effects of continuous positive airway pressure (CPAP) therapy on anxiety and depression in 72 patients with obstructive sleep apnea (OSA), both with and without coronary…

Heart LungMay 2, 2026Read summary
Clinical ResearchCardiologyOpen access

Sources of Heterogeneity in the Efficacy of Statins for Primary Prevention of Cardiovascular Diseases: A Systematic Review with Meta-Regression and Meta-Analysis of Within-Study Subgroup Differences.

This systematic review and meta-analysis evaluated the efficacy of statins for primary prevention of cardiovascular disease (CVD) in 102,667 adults without prior CVD.

Cardiovasc Drugs TherMay 2, 2026Read summary
Case ReportOncology (Medical)

A Case of Myocardial Ischemia Detected in a Standard Oncological FDG PET/CT Study.

An 84-year-old man with rectosigmoid adenocarcinoma underwent 18 F-FDG PET/CT for staging. The imaging revealed an incidental focal uptake in the left ventricle, which was associated with clinical symptoms.

Clin Nucl MedMay 1, 2026Read case

April 20265

Clinical ResearchCardiologyOpen access

Effect of intensive versus standard blood pressure control on cardiovascular outcomes: a meta-analysis of randomized controlled trials.

This meta-analysis evaluated the effects of intensive versus standard blood pressure control on cardiovascular outcomes in 156,933 hypertensive patients across 31 randomized controlled trials.

Ann MedApr 30, 2026Read summary
Clinical ResearchCardiologyOpen access

A systematic review with meta-analysis on racial and ethnic disparities in acute venous thromboembolism diagnosis and management.

This systematic review and meta-analysis examined racial and ethnic disparities in the diagnosis and management of acute venous thromboembolism (VTE) among U.S. adults.

J Vasc Surg Venous Lymphat DisordApr 30, 2026Read summary
Clinical ResearchNephrologyOpen access

Mineralocorticoid receptor antagonists in dialysis patients after ACHIEVE and ALCHEMIST: updated systematic review and meta-analysis of 14 randomized trials.

This systematic review and meta-analysis evaluated the efficacy and safety of mineralocorticoid receptor antagonists (MRAs) in 4,525 dialysis patients across 14 randomized trials.

Ren FailApr 29, 2026Read summary
Case ReportInternal Medicine (General)

Probable interaction between warfarin and a toothache solution containing Piper longum L. leading to ischemic stroke: a case report.

A patient with a mechanical heart valve on warfarin experienced fluctuations in their international normalized ratio (INR) and subsequently suffered an ischemic stroke.

J EthnopharmacolApr 29, 2026Read case
Clinical ResearchCardiology

Identification of clinical risk factors for arrhythmia recurrence in patients with atrial fibrillation undergoing catheter ablation: A systematic review and meta-analysis.

This systematic review and meta-analysis examined clinical risk factors for arrhythmia recurrence in patients with atrial fibrillation (AF) post-catheter ablation, analyzing data from 152 studies with 49,919 patients.

Heart RhythmApr 29, 2026Read summary

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