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1018 articles

May 20267

Clinical ResearchOphthalmologyOpen access

Gestational Age-Specific Prevalence of Retinopathy of Prematurity in Very Preterm Infants: An Exploratory Meta-Analysis.

This meta-analysis evaluated the prevalence of Retinopathy of Prematurity (ROP) in very preterm infants, focusing on gestational age (GA) thresholds versus birth weight (BW) criteria.

Acta PaediatrMay 4, 2026Read summary
Case ReportInfectious DiseasesOpen access

Infliximab in a Child With Relapsing Tuberculous Meningoencephalitis: A Case Report and Literature Review.

A 5-year-old child with tuberculous meningoencephalitis experienced severe drug-induced hepatitis following standard antitubercular therapy, leading to the discontinuation of treatment.

Pediatr Infect Dis JMay 4, 2026Read case
Clinical ResearchPediatrics

Impact of Probiotics on Children with Acute Gastroenteritis: Results from an Umbrella Meta-Analysis.

This umbrella meta-analysis assessed probiotic efficacy for acute gastroenteritis in children, synthesising 36 meta-analyses with 107,541 participants.

J Integr Complement MedMay 4, 2026Read summary
Clinical ResearchPediatrics

The effect of maternal scent-infused blanket on the stress level, crying duration and physiological parameters of premature newborns.

This randomized controlled trial assessed the impact of a maternal scent-infused blanket on stress levels, crying duration, and physiological parameters in 69 premature infants in the NICU.

J Matern Fetal Neonatal MedMay 3, 2026Read summary
Clinical ResearchNephrology

Renal osteodystrophy in pediatric patients. A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated histomorphometric findings in 980 bone biopsies from pediatric patients with chronic kidney disease (CKD).

BoneMay 2, 2026Read summary
Clinical ResearchPediatrics

Effects of Endotracheal Suctioning With Expiratory Pause in Infants.

This randomized controlled trial evaluated the effectiveness of closed endotracheal suctioning with an expiratory pause in infants on invasive mechanical ventilation.

Respir CareMay 2, 2026Read summary
Clinical ResearchPediatricsOpen access

Local application of otoprotective compounds other than sodium thiosulfate to prevent cisplatin-induced hearing loss: a systematic review.

This systematic review evaluated the efficacy and safety of locally applied otoprotective agents other than sodium thiosulfate (STS) to prevent cisplatin-induced hearing loss in pediatric cancer patients.

Drug DelivMay 1, 2026Read summary

April 202617

Clinical ResearchOphthalmology

Strabismus surgery outcomes in pediatric patients with developmental delay: a meta-analysis and systematic review.

This meta-analysis evaluated strabismus surgery outcomes in pediatric patients with developmental delays, comparing them to children without such delays. The analysis included 31 studies with 3687 subjects.

StrabismusApr 30, 2026Read summary
Clinical ResearchPediatrics

The Impact of Dosing Schedule on the Efficacy of Hand-Arm Bimanual Intensive Therapy Including the Lower Extremities (HABIT-ILE) in Children With Bilateral Cerebral Palsy.

This randomized controlled trial evaluated the efficacy of two dosing schedules of Hand-Arm Bimanual Intensive Therapy Including the Lower Extremities (HABIT-ILE) in 21 children aged 5 to 17 years with bilateral…

Neurorehabil Neural RepairApr 30, 2026Read summary
Clinical ResearchPediatricsOpen access

Improving oral health communication in paediatric dentistry using intraoral scanners: a multicentre pilot study.

This multicentre randomized controlled trial evaluated the effectiveness of intraoral scanners (IOS) in enhancing oral health communication among 60 children aged 6-14 and their caregivers.

Eur Arch Paediatr DentApr 29, 2026Read summary
Clinical ResearchPediatrics

Growth and human milk intake outcomes from postdischarge feedings among very-low-birth-weight preterm infants: A systematic review.

This systematic review evaluated the effects of postdischarge fortified human milk (HM) or breastfeeding with formula on growth and HM intake in very-low-birth-weight preterm infants.

Nutr Clin PractApr 29, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Effectiveness Comparison of Kinect-Based and Therapist-Based Bimanual Intensive Training in Children With Unilateral Cerebral Palsy: A Randomized Controlled Trial.

This randomized controlled trial compared Kinect-based bimanual intensive training (K-BIT) and therapist-based bimanual intensive training (T-BIT) in 31 children with unilateral cerebral palsy.

Arch Phys Med RehabilApr 28, 2026Read summary
Case ReportCardiology

Supracardiac Total Anomalous Pulmonary Venous Connection with Left Main Bronchial Compression in an Infant.

A 4-month-old male infant presented with supracardiac total anomalous pulmonary venous connection (TAPVC) and left main bronchial stenosis, alongside a central atrial septal defect and severe pulmonary hypertension.

World J Pediatr Congenit Heart SurgApr 28, 2026Read case
Clinical ResearchPediatrics

Short-course Intravenous Antibiotic Therapy of Pediatric Acute Bone and Joint Infections: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of short-course intravenous antibiotic therapy (≤5 days) in previously healthy children with acute bone and joint infections (BJIs).

Pediatr Infect Dis JApr 27, 2026Read summary
Clinical ResearchOphthalmology

Optical coherence tomography measurements in retinopathy of prematurity: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated retinal and choroidal structural changes in individuals with a history of retinopathy of prematurity (ROP) compared to healthy controls.

Eur J OphthalmolApr 27, 2026Read summary
Case ReportMedical Genetics

Response of an Infant With Presumed Multiple Acyl-CoA Dehydrogenase Deficiency (MADD) to Ketone Supplementation.

An infant diagnosed with Multiple Acyl-CoA Dehydrogenase Deficiency (MADD) exhibited severe cardiac dysfunction. Despite genome sequencing failing to identify pathogenic variants, RNA sequencing indicated reduced ETFB…

Am J Med Genet AApr 27, 2026Read case
Clinical ResearchPediatrics

Clinical Evaluation of Pit and Fissure Sealants Placed by Intern Dental Students After Tele-Demonstration Technique.

This randomized controlled trial compared pit and fissure sealants placed by dental interns after direct clinical demonstration or tele-education using a pre-recorded video.

Eur J Dent EducApr 27, 2026Read summary
Clinical ResearchPsychiatry

Investigating inequalities in children and young people's mental healthcare and outcomes: prospective longitudinal analysis from the STADIA trial.

This prospective longitudinal analysis of data from the STADIA randomised controlled trial examined access to care and outcomes among 1,225 children aged 5–17 years referred to child and adolescent mental health…

Br J PsychiatryApr 27, 2026Read summary
Clinical ResearchEndocrinology

The effect of the healthy lifestyle 'empowerment program' on care burden and adherence to health-promoting behaviours on mothers of children with type 1 diabetes.

This randomized controlled trial assessed the Healthy Lifestyle Empowerment Program (HLEP) for mothers of children with type 1 diabetes (T1D) in Tehran.

Glob Public HealthApr 25, 2026Read summary
Clinical ResearchPsychiatry

Varenicline for nicotine cessation in youth: A meta-analysis of randomized controlled trials addressing FDA labeling gaps in age and product use.

This meta-analysis evaluated the effectiveness and safety of varenicline for nicotine cessation in young adults aged 12 to 26 years, analyzing data from five randomized controlled trials.

J Subst Use Addict TreatApr 25, 2026Read summary
Clinical ResearchPediatricsOpen access

Balanced Fluid or 0.9% Saline in Children Treated for Septic Shock.

This randomized controlled trial evaluated the effects of balanced crystalloid fluid versus 0.9% saline in 8,482 children aged 2 months to <18 years with suspected septic shock.

N Engl J MedApr 24, 2026Read summary
Case ReportMedical Genetics

Cornelia de Lange syndrome in an extremely low birth weight infant: a case report.

An infant born by emergency cesarean delivery at 34 weeks and 1 day weighed 994 g (-3.7 SD score). Cornelia de Lange syndrome (CdLS) was suspected from dysmorphic findings including forehead and femoral hirsutism, cleft…

Fukushima J Med SciApr 24, 2026Read case
Clinical ResearchOncology (Medical)Open access

Electrochemotherapy in pediatrics: a systematic review.

This systematic review evaluated electrochemotherapy (ECT) in pediatric patients, analyzing 15 studies involving at least 127 children.

Eur RadiolApr 22, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Maternal Chikungunya virus infection and pregnancy outcomes: a global systematic review and meta-analysis of vertical transmission dynamics and associated morbidity.

This systematic review and meta-analysis evaluated the impact of maternal Chikungunya virus (CHIKV) infection on pregnancy outcomes, analyzing 57 observational studies.

Emerg Microbes InfectApr 21, 2026Read summary

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