Trending archive

Every article that has appeared in Trending stays here. Search by title, journal, author or PMID, and narrow by date.

1088 articles

April 202624

Clinical ResearchPsychiatry

Nurses' Experiences of Pain Management for Patients With Diagnosed Mental Health Conditions: A Systematic Review.

This mixed-methods systematic review synthesised evidence on nurses’ pain assessment and management for patients with diagnosed mental health conditions.

J Adv NursApr 29, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Efficacy and safety of menopausal hormone therapy for depressive symptoms in perimenopausal women: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effects of hormone replacement therapy (HRT) on depressive symptoms in perimenopausal women.

J Affect DisordApr 28, 2026Read summary
Clinical ResearchPsychiatry

Joint physical activity and screen time patterns in relation to mental health and sleep among university students: A systematic review with exploratory quantitative synthesis.

This systematic review examined the relationship between joint patterns of physical activity (PA) and screen time (ST) on mental health and sleep among university students.

J Affect DisordApr 28, 2026Read summary
Case ReportPsychiatry

Atomoxetine and the risk of mania: a case report on bipolar disorder in an ADHD patient and its dilemmas.

A 20-year-old male with a history of ADHD, treated with atomoxetine and risperidone, developed manic symptoms following a depressive episode after bereavement.

Int J Psychiatry Clin PractApr 28, 2026Read case
Clinical ResearchPsychiatry

Toward Precision Psychiatry: Using Clinical and Pharmacokinetic Data to Increase Antidepressant Dose or Change Treatment in Late-Life Depression.

This randomized controlled trial investigated the use of clinical, pharmacogenetic, and pharmacokinetic data to guide treatment decisions in older patients with major depressive disorder (MDD) who did not fully respond…

J Clin PsychopharmacolApr 28, 2026Read summary
Clinical ResearchPsychiatryOpen access

Evaluating comparative effect of non-pharmacological interventions adjunctive to opioid agonist therapy for opioid use disorder: A systematic review with network meta-analysis.

This systematic review and network meta-analysis evaluated the efficacy of non-pharmacological interventions as adjuncts to opioid agonist therapy (OAT) in patients with opioid use disorder (OUD).

AddictionApr 28, 2026Read summary
Clinical ResearchPsychiatryOpen access

Sustained mental health outcomes from the youth readiness intervention: A four-year effectiveness follow-up of a hybrid type II trial in Sierra Leone.

This study evaluated the long-term mental health outcomes of the Youth Readiness Intervention (YRI) combined with entrepreneurship training (ENTR) in Sierra Leone, four years post-intervention.

J Child Psychol PsychiatryApr 27, 2026Read summary
Clinical ResearchGeriatrics

Promoting digital memory aid use in older adults with cognitive concerns: A pilot randomized controlled trial of adaptive web-based training.

This pilot randomized controlled trial evaluated a web-based training platform for older adults with cognitive concerns, comparing self-guided support to clinician-supported sessions.

NeuropsychologyApr 27, 2026Read summary
Clinical ResearchPsychiatry

Feared self and responsibility in obsessive compulsive phenomena.

This online randomized experiment examined whether heightened responsibility and feared-self cues influence obsessive-compulsive tendencies in 185 participants (mean age 28.11 years).

Br J Clin PsycholApr 27, 2026Read summary
Clinical ResearchPsychiatry

Manual therapy modalities and depression: a systematic review.

This systematic review assessed published studies of manual-therapy modalities and depressive symptoms, including studies involving people with diagnosed mood disorders.

J Osteopath MedApr 27, 2026Read summary
Clinical ResearchPsychiatry

Investigating inequalities in children and young people's mental healthcare and outcomes: prospective longitudinal analysis from the STADIA trial.

This prospective longitudinal analysis of data from the STADIA randomised controlled trial examined access to care and outcomes among 1,225 children aged 5–17 years referred to child and adolescent mental health…

Br J PsychiatryApr 27, 2026Read summary
Clinical ResearchPsychiatry

Circulating Growth Differentiation Factor-15 (GDF-15) levels in depressive disorders - A systematic review and meta-analysis of the association between GDF-15 and depression in adult populations.

This systematic review and meta-analysis evaluated the association between circulating Growth Differentiation Factor-15 (GDF-15) levels and depression in adult populations.

J Affect DisordApr 26, 2026Read summary
Clinical ResearchPsychiatry

Varenicline for nicotine cessation in youth: A meta-analysis of randomized controlled trials addressing FDA labeling gaps in age and product use.

This meta-analysis evaluated the effectiveness and safety of varenicline for nicotine cessation in young adults aged 12 to 26 years, analyzing data from five randomized controlled trials.

J Subst Use Addict TreatApr 25, 2026Read summary
Clinical ResearchGeriatricsOpen access

Brief intervention for inappropriate z-hypnotics use in older adults: a before and after intervention study in primary care.

This randomized controlled trial evaluated the long-term effects of a brief intervention for inappropriate z-hypnotic use in older adults within primary care.

Scand J Prim Health CareApr 24, 2026Read summary
Clinical ResearchPsychiatry

Antenatal psychological interventions may ameliorate postpartum depression: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of antenatal psychological interventions on postpartum depression in pregnant women without severe mental illness.

J Obstet GynaecolApr 24, 2026Read summary
Clinical ResearchPlastic Surgery

Depression and anxiety changes in patients after orthognathic surgery: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effects of orthognathic surgery on depression and anxiety in patients with dentofacial deformities, analyzing 12 studies with 613 participants.

Br J Oral Maxillofac SurgApr 24, 2026Read summary
Clinical ResearchPsychiatryOpen access

Stimulant use and increased severity of opioid use disorder and mental illness in patients with co-occurring disorders.

This cross-sectional study examined the relationship between stimulant use and the severity of opioid use disorder (OUD) and mental illness in primary care patients with co-occurring depression and/or PTSD.

J Subst Use Addict TreatApr 24, 2026Read summary
Clinical ResearchPsychiatry

A relational agent for treating substance use in adults: A randomized controlled trial with a psychoeducational comparator.

This randomized controlled trial evaluated the efficacy of the Woebot for Substance Use Disorders (W-SUD) app in reducing substance use occasions among U.S. adults with problematic substance use.

J Subst Use Addict TreatApr 24, 2026Read summary
Clinical ResearchGastroenterology

The influence of C-reactive protein on depression in inflammatory bowel disease: A systematic review and meta-analysis.

This systematic review and meta-analysis examined the relationship between C-reactive protein (CRP) levels and depression in patients with inflammatory bowel disease (IBD).

J Affect DisordApr 24, 2026Read summary
Clinical ResearchNeurologyOpen access

The effects of the PDE4 inhibitor roflumilast on cognitive performance after a cerebrovascular accident: a double-blind randomized placebo-controlled trial with an open label extension (ROSTMEMA).

This double-blind randomized placebo-controlled trial evaluated the effects of the PDE4 inhibitor roflumilast on cognitive performance in 100 post-stroke patients aged 41-70 with memory complaints.

J PsychopharmacolApr 24, 2026Read summary
Clinical ResearchNeurology

Prebiotics/synbiotics as natural alternatives for brain development and aging - focus on nutrigenomic and direct effects: a systematic review.

This systematic review examines the role of prebiotics and synbiotics in brain development and neurodegenerative diseases, analyzing 79 studies including human and animal research.

Nutr NeurosciApr 24, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Neuroendocrine signature of ME/CFS: Meta-analytic evidence for bioactive cortisol deficit and exaggerated feedback sensitivity.

This meta-analysis examined the neuroendocrine profile of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) by analyzing 46 studies with 1388 patients.

Mol PsychiatryApr 23, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Qinghao Biejia Decoction Combined with Auricular Acupoint Seed Embedding in Improving TCM Syndromes and Sleep Parameters in Perimenopausal Insomnia Patients.

This randomized controlled trial evaluated the efficacy of Qinghao Biejia Decoction (QBD) combined with auricular acupoint seed embedding (AASE) in 160 perimenopausal women aged 45-55 with insomnia.

Behav Sleep MedApr 23, 2026Read summary
Clinical ResearchPsychiatry

Risk of stroke among individuals on selective serotonin reuptake inhibitors (SSRIs) versus non-SSRI antidepressants: a population-based retrospective cohort study and meta-analysis.

This population-based retrospective cohort study and meta-analysis evaluated the stroke risk associated with selective serotonin reuptake inhibitors (SSRIs) compared to non-SSRI antidepressants among 124,854 patients in…

J Affect DisordApr 22, 2026Read summary

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text

Prefer listening? Personalized audio digests are available with Pro.