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1998 articles

October 202624

Clinical ResearchAnesthesiologyOpen access

Intraoperative Dexmedetomidine and Postoperative Delirium After Head and Neck Cancer Surgery with Free-Flap Reconstruction: A Secondary Analysis of a Randomized Placebo-Controlled Trial.

This delirium-focused secondary analysis of a single-centre, randomized, double-blind, placebo-controlled trial examined adults undergoing elective head and neck cancer surgery with free-flap reconstruction.

Drug Des Devel TherOct 2, 2026Read summary
Clinical ResearchPediatricsOpen access

Postnatal interventions to support newborn survival: updates for the Lives Saved Tool.

This systematic review evaluated postnatal interventions aimed at reducing neonatal mortality, particularly in low- and middle-income countries.

J Glob HealthOct 2, 2026Read summary
Clinical ResearchOrthopedic Surgery

Outcome assessment in frozen shoulder trials: A systematic review and COSMIN-informed recommendations.

This systematic review mapped outcome measures in 927 randomized controlled trials (RCTs) of frozen shoulder and conducted a COSMIN-informed appraisal of measurement-property evidence for commonly used instruments.

Complement Ther MedOct 2, 2026Read summary
Case ReportNeurology

Amyotrophic Lateral Sclerosis.

This article describes the nerve loss underlying amyotrophic lateral sclerosis, its clinical manifestations, examination findings leading to the diagnosis, the expanding role of genetics, and available treatment and…

Continuum (Minneap Minn)Oct 2, 2026Read case
Clinical ResearchPsychiatryOpen access

A Randomized Controlled Trial of a Digital Stepped-Care Program to Reduce Anxiety and Depressive Symptoms Among Long-Term Care Workers With Psychological Distress: The REPICAL Study.

The REPICAL study evaluated a digital stepped-care program aimed at reducing anxiety and depressive symptoms among long-term care workers (LTCWs) in Catalonia, Spain.

Depress AnxietyOct 2, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Effects of stellate ganglion block on postoperative sleep disturbance: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effects of stellate ganglion block (SGB) on postoperative sleep disturbance in 734 participants from 10 randomized controlled trials.

Sleep BreathOct 2, 2026Read summary
Case ReportMedical Genetics

Hereditary Neuropathies.

This article describes the clinical features, genetic causes, and diagnostic strategies of inherited peripheral neuropathies, and highlights how recent developments are reshaping the management of these disorders.

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportPediatrics

Spinal Muscular Atrophy.

This article reviews the history, epidemiology, genetics, clinical presentation, multidisciplinary management, and established and emerging therapies for patients with spinal muscular atrophy.

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportNeurology

Chronic Inflammatory Demyelinating Polyradiculoneuropathy.

This article describes the cardinal clinical, electrophysiologic, and supportive features of typical CIDP and its variants, how to review and apply CIDP diagnostic criteria, objective measures that can be used in…

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportNeurology

Nutritional and Toxic Neuropathies.

This article reviews the etiologies, clinical presentations, and management of nutritional and toxic neuropathies.

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportNeurology

Diabetic Neuropathies.

This article provides an update on the biological mechanisms and risk factors for the varied manifestations of diabetes-associated nerve injury, and reviews current diagnostic and treatment approaches.

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportNeurology

Amyloid Neuropathies.

This article reviews the pathophysiology, epidemiology, and clinical features of amyloid neuropathies, with a focus on light chain (AL) amyloidosis and hereditary amyloidogenic transthyretin (ATTRv) amyloidosis, and…

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportNeurology

Wellness and Career Sustainability in Neurology.

This article reviews drivers of well-being in neurology, using the practice of neuromuscular neurology as an example and high-yield interventions to enhance professional fulfillment.

Continuum (Minneap Minn)Oct 2, 2026Read case
Clinical ResearchOncology (Medical)

Tumor-Free Circulating Tumor DNA in Node-Negative Rectal Cancers Undergoing Neoadjuvant Chemotherapy, Excision, and Observation in the Phase II NEO Trial (CO.28).

The Phase II NEO trial investigated the role of circulating tumor DNA (ctDNA) in guiding treatment decisions for 53 patients with node-negative rectal cancer undergoing neoadjuvant chemotherapy and transanal excision.

JCO Precis OncolOct 2, 2026Read summary
Case ReportNeurology

Guillain-Barré Syndrome.

This article reviews the epidemiology, clinical symptoms, examination findings, pathogenesis, diagnostic criteria, and recent guidelines of Guillain-Barré syndrome (GBS) and its variants, including information on…

Continuum (Minneap Minn)Oct 2, 2026Read case
Clinical ResearchMedical GeneticsOpen access

Short-chain enoyl-CoA hydratase deficiency: a systematic review of clinical spectrum, genotype-phenotype correlations and survival predictors.

This systematic review examined short-chain enoyl-CoA hydratase 1 (SCEH) deficiency in 165 patients with confirmed ECHS1 variants.

NeurogeneticsOct 2, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Maternal and fetal outcomes of spinal tuberculosis in pregnancy: A systematic review and descriptive pooled analysis.

Spinal tuberculosis (TB) in pregnancy is rare and poses diagnostic, neurological, and obstetric challenges. Data are limited to isolated case reports and small series, precluding evidence-based guidance on management…

Neurosurg RevOct 2, 2026Read summary
Case ReportEndocrinology

Thyrotoxicosis-Associated Cholestatic Jaundice in a Patient With Incidental Gallstone Disease: A Case Report and Literature Review.

A 62-year-old woman presented with right upper quadrant pain, weight loss, and jaundice. Laboratory tests indicated cholestatic liver injury, and imaging revealed a solitary gallstone and signs of right-sided heart…

Am J Case RepOct 2, 2026Read case
Clinical ResearchNeurologyOpen access

Cerebrospinal fluid shunting for idiopathic normal pressure hydrocephalus: a comprehensive meta‑analysis with trial sequential analysis of randomized controlled trials.

This meta-analysis evaluated the efficacy of cerebrospinal fluid (CSF) shunting in adults aged 60 and older with idiopathic normal pressure hydrocephalus (iNPH).

Neurol SciOct 2, 2026Read summary
Case ReportHematologyOpen access

Concurrent presentation of distinct extranodal and splenic marginal zone lymphomas.

A patient was diagnosed with both extranodal marginal zone lymphoma (EMZL) of the ocular adnexa and splenic marginal zone lymphoma (SMZL).

J HematopOct 2, 2026Read case
Case ReportNeurosurgeryOpen access

Endoscopic third ventriculostomy for diencephalosynapsis-related hydrocephalus in MPDZ gene syndrome: a case report and review of the literature.

A female infant with prenatally diagnosed obstructive ventriculomegaly was confirmed to have MPDZ syndrome through whole-exome sequencing.

Childs Nerv SystOct 2, 2026Read case
Clinical ResearchPediatricsOpen access

Therapeutic value of continuous subcutaneous insulin infusion with electrolyte supplementation for pediatric diabetic ketoacidosis.

This randomized controlled trial evaluated the efficacy and safety of continuous subcutaneous insulin infusion (CSII) with electrolyte supplementation in 66 pediatric patients with diabetic ketoacidosis (DKA).

Eur J PediatrOct 2, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Effectiveness of a nurse-led telephonic brief intervention to reduce risky alcohol use among women in primary care in Brazil: a randomized controlled trial.

This randomized controlled trial evaluated a nurse-led telephonic brief intervention aimed at reducing risky alcohol use among 151 women in primary care in São Paulo, Brazil.

Arch Womens Ment HealthOct 2, 2026Read summary
Clinical ResearchPlastic SurgeryOpen access

Treatment of hypertrophic scars using fractional CO2 laser alone in comparison with adding botulinium toxin either intalesional injection or assisted drug delivery.

This randomized controlled trial evaluated the effectiveness of fractional CO₂ laser treatment alone versus its combination with botulinum toxin A in 16 patients with post-burn hypertrophic scars.

Lasers Med SciOct 2, 2026Read summary

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