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1333 articles
September 202624
External validation of the NADIR model for early prostate-specific antigen response prediction in enzalutamide-treated metastatic hormone-sensitive prostate cancer: An analysis of the ARCHES trial.
This validation study assessed the NADIR model's ability to predict early prostate-specific antigen (PSA) response in 558 enzalutamide-treated patients from the ARCHES trial.
Low-intensity pulsed ultrasound to facilitate uterine involution: prospective multicenter study on clinical efficacy and mechanistic insights.
This multicenter, randomized controlled trial evaluated the efficacy of low-intensity pulsed ultrasound (LIPUS) in promoting uterine involution post-delivery among 1,106 women.
Cost-effectiveness of heart failure pharmacotherapy withdrawal in recovered atrial fibrillation mediated cardiomyopathy: analysis of the WITHDRAW-AF randomized clinical trial.
This economic analysis of the WITHDRAW-AF randomized clinical trial compared heart failure pharmacotherapy withdrawal with continuation in carefully selected patients with recovered atrial fibrillation-mediated…
Longitudinal impact of sodium bicarbonate therapy on health-related quality of life in pre-dialysis chronic kidney disease with metabolic acidosis: a pragmatic trial in Malaysia.
This pragmatic clinical trial evaluated the impact of sodium bicarbonate therapy on health-related quality of life (HRQoL) in 74 pre-dialysis chronic kidney disease (CKD) patients with metabolic acidosis over 18 months.
Determinants of preterm pre-eclampsia following low-dose aspirin prophylaxis: evidence from stepped-wedge cluster randomized trial in Asia.
This multicenter stepped-wedge cluster randomized trial studied 2919 high-risk pregnant women receiving low-dose aspirin prophylaxis to identify risk factors for preterm pre-eclampsia (PE).
GLP-1 Receptor Agonists in Heart Failure: A Systematic Review and Meta-analysis with Phenotype-Specific Effects and Dual Analytical Frameworks.
This systematic review and random-effects meta-analysis assessed GLP-1 receptor agonists across heart-failure phenotypes and trial types, including 14 trials and 15,882 patients with heart failure.
Virtual reality as a non-pharmacological adjuvant for anxiety in oncology care: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness of virtual reality (VR) interventions for managing anxiety in cancer patients.
Effect of Multi-Modal Training in Patients With Mild Cognitive Impairment: A Randomized Controlled Pilot Trial.
This pilot randomized controlled trial evaluated the effects of a 24-week multi-modal training program on cognitive function in 65 older adults with mild cognitive impairment (MCI).
Long-term outcome after partial breast irradiation with interstitial multi-catheter high-dose-rate brachytherapy: Results from a Phase II prospective study with extended follow-up.
This prospective observational Phase II study assessed late toxicity, cosmesis, and cancer outcomes after partial breast irradiation with interstitial multi-catheter high-dose-rate brachytherapy.
Exploring the impact of artificial intelligence on radiation dose reduction in urological imaging: a systematic review from EAU endourology.
This systematic review evaluated the impact of artificial intelligence (AI) on radiation dose reduction in urological CT imaging.
Effectiveness of Lactobacillus-supplemented eradication therapy for Helicobacter pylori: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the effectiveness of Lactobacillus-supplemented Helicobacter pylori eradication therapy across 32 randomized controlled trials involving 4,010 patients.
Help-seeking behavior and its determinants among gender-based violence survivor women in Africa: A systematic review and meta-analysis.
This systematic review and random-effects meta-analysis estimated help-seeking among women who had experienced gender-based violence in Africa and examined associated factors.
Routine versus clinically indicated cerebrospinal fluid sampling for infection in external ventricular drains: a systematic review.
This systematic review evaluated the effectiveness of routine versus clinically indicated cerebrospinal fluid (CSF) sampling for infection in patients with external ventricular drains (EVDs).
Mineralocorticoid receptor stimulation effects on stress-induced cortisol and alpha-amylase in female patients with borderline personality disorder and healthy controls: A randomized placebo-controlled experimental study.
This double-blind, randomized, placebo-controlled experimental study examined mineralocorticoid receptor stimulation and stress responses in 120 female patients with borderline personality disorder (BPD) and 120 healthy…
Robotic versus laparoscopic surgery in older adults: a systematic review and meta-analysis of recovery-centered outcomes.
This systematic review and meta-analysis evaluated recovery-centered outcomes of robotic versus laparoscopic surgery in older adults, analyzing 41 observational studies.
Molecular biomarkers as key determinants of outcome in mantle cell lymphoma: results from the FIL V-RBAC trial.
This phase II clinical trial analyzed the molecular landscape of 132 older patients with mantle cell lymphoma (MCL) from the FIL V-RBAC trial.
Carfilzomib plus induction chemotherapy for children with relapsed or refractory acute lymphoblastic leukemia.
This phase II clinical trial evaluated the efficacy of carfilzomib combined with induction chemotherapy (CFZ-VXLD) in pediatric patients aged 1 month to <21 years with relapsed or refractory acute lymphoblastic leukemia…
Does Dosage Drive Durability? A Longitudinal Study on Digital Cognitive Training for Sustained Functional Independence.
This randomized controlled trial examined the effects of digital cognitive training (DCT) on cognition and functionality in older adults with Mild Neurocognitive Disorder.
Acquired paroxysmal dysarthria-ataxia syndrome: A systematic review of clinical and MRI findings.
This systematic review examined acquired paroxysmal dysarthria-ataxia syndrome (PDAS) in 31 patients across 25 studies, revealing that PDAS is not limited to Multiple Sclerosis.
Early cardiovascular vulnerability after acute exacerbation of COPD: a time-windowed systematic review and evidence map.
This systematic review and evidence map examined cardiovascular events during and after exacerbations of COPD, asthma, or bronchiectasis, with COPD as the primary evidence base.
Clinical Characteristics and Factors Associated with One-Year Smoking Cessation Among Smokers with COPD: A Subgroup Analysis of a Multicentre Randomised Trial.
This multicentre randomised trial evaluated factors associated with one-year smoking cessation among smokers with COPD. Of 172 patients analyzed, 32 (18.6%) achieved cessation, with 25.8% in the immediate referral group…
Liposomal Bupivacaine versus Bupivacaine Hydrochloride Plus Dexamethasone for Combined Adductor Canal and iPACK Blocks in Total Knee Arthroplasty: A Randomized Controlled Trial.
This randomized controlled trial compared postoperative analgesia and quadriceps recovery between liposomal bupivacaine and bupivacaine hydrochloride plus dexamethasone in 60 patients undergoing total knee arthroplasty.
A machine learning-based ecological momentary intervention for mental health promotion in youth: a micro-randomized trial.
This micro-randomized trial investigated the effects of machine learning (ML)-based ecological momentary interventions (EMIs) on mental health outcomes in 49 youth participants.
Quantifying Pancreatic Fat Using a Free-Breathing Acquisition in Adults With Obesity Undergoing Diet-Induced Weight Loss-Results From the LION Study.
This randomized controlled trial evaluated a free-breathing six-echo radial stack-of-stars acquisition for quantifying pancreatic fat in 18 adults with obesity undergoing diet-induced weight loss.
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