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1998 articles

October 202624

Clinical ResearchGeneral Surgery

A systematic review and meta-analysis of preoperative MRI-based pelvimetry in predicting surgical difficulty in rectal cancer: Implications for personalised surgical planning.

This systematic review and meta-analysis evaluated the role of MRI-based pelvimetry in predicting surgical difficulty during total mesorectal excision (TME) for rectal cancer, involving 8,364 patients across 36 studies.

Colorectal DisOct 1, 2026Read summary
Case ReportNeurosurgery

How I do it: meningioangiomatosis of the sylvian fissure. The need for a tailored functional neurosurgery.

A patient with drug-resistant epileptic seizures presented with meningioangiomatosis located in the right sylvian fissure, affecting the M1-M2 segments of the right middle cerebral artery.

Acta Neurochir (Wien)Oct 1, 2026Read case
Clinical ResearchPlastic Surgery

Hair Follicle-Derived Grafting for Chronic Cutaneous Wounds: A Systematic Review of Clinical Outcomes.

This systematic review evaluated the clinical outcomes of hair follicle-derived grafting techniques for chronic cutaneous wounds, analyzing 16 studies with 239 patients.

Int Wound JOct 1, 2026Read summary
Clinical ResearchOrthopedic Surgery

Efficacy of US-guided Hydrodissection for Carpal Tunnel Syndrome: A Prospective Randomized Controlled Trial.

This prospective randomized controlled trial evaluated the efficacy of three US-guided hydrodissection techniques for treating carpal tunnel syndrome (CTS) in adults with refractory symptoms.

RadiologyOct 1, 2026Read summary
Clinical ResearchCardiology

Quercetin in Myocardial Ischemia-Reperfusion Injury: Mechanistic Evidence, Cardioprotective Effects, and Translational Challenges.

This systematic review assessed the cardioprotective effects of quercetin in myocardial ischemia-reperfusion (I/R) injury, primarily in preclinical studies.

J Biochem Mol ToxicolOct 1, 2026Read summary
Clinical ResearchRheumatology

Temporal Patterns of Outcomes After DMARD Tapering or Withdrawal in Rheumatoid Arthritis With Sustained Disease Control: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the effects of DMARD tapering and withdrawal in patients with rheumatoid arthritis (RA) who had sustained disease control.

Clin Transl SciOct 1, 2026Read summary
Clinical ResearchCardiology

Effectiveness of a Sodium Intake Monitoring Smartphone Application (NamakBan) on Clinical Outcomes of Patients Diagnosed With Hypertension: A Randomized Clinical Trial.

This randomized clinical trial evaluated the effectiveness of the NamakBan smartphone application for monitoring sodium intake in 88 adults with primary hypertension.

Nurs OpenOct 1, 2026Read summary
Clinical ResearchInfectious Diseases

Association of white blood cell count with treatment response to cefepime versus piperacillin-tazobactam.

This randomized controlled trial analyzed the impact of white blood cell (WBC) count on the effectiveness of cefepime versus piperacillin-tazobactam in treating sepsis.

Am J Respir Crit Care MedOct 1, 2026Read summary
Clinical ResearchOrthopedic Surgery

Topical Anesthetics Effectiveness in Management of Orthodontic Pain: A Systematic Review of Randomized Controlled Trials.

This systematic review evaluated the effectiveness of topical anesthetics in managing orthodontic pain, analyzing nine randomized controlled trials involving 456 participants aged 14-35.

Clin Exp Dent ResOct 1, 2026Read summary
Clinical ResearchDermatology

Contact Allergens Associated With Nummular Eczema: A Systematic Review.

This systematic review examined the association between contact allergens and nummular eczema (NE) by analyzing 10 observational studies.

J Drugs DermatolOct 1, 2026Read summary
Clinical ResearchNeurology

NIHSS and Large Artery Atherosclerosis Affect Efficacy of Dual Antiplatelet Therapy Versus Alteplase for Minor Stroke.

This randomized controlled trial analyzed the efficacy of dual antiplatelet therapy (DAPT) versus alteplase in patients with minor stroke (NIHSS 0-5) and assessed the impact of large artery atherosclerosis (LAA).

Brain BehavOct 1, 2026Read summary
Case ReportCardiology

Apheresis-Triggered Torsades De Pointes in Congenital Long QT Syndrome Type 2: Citrate-Related Arrhythmia Risk and Safe Modality Switching During Myasthenic Crisis.

A 44-year-old woman with congenital long QT syndrome Type 2 presented in myasthenic crisis due to anti-MuSK-positive myasthenia gravis.

J Clin ApherOct 1, 2026Read case
Case ReportOrthopedic SurgeryOpen access

Modified tibiofibular synostosis vs. Burgess stump in a bilateral amputee: a case report.

A bilateral transtibial amputee had a modified tibiofibular synostosis (TFS) stump on the right and a conventional Burgess-type stump (BTS) on the left.

BMC Musculoskelet DisordOct 1, 2026Read case
Clinical ResearchPulmonologyOpen access

Efficacy and Safety of Traditional Chinese Medicine in Treating Chronic Obstructive Pulmonary Disease with Osteoporosis: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the efficacy and safety of traditional Chinese medicine (TCM) as an adjunct to conventional treatment for chronic obstructive pulmonary disease (COPD) with osteoporosis…

Int J Chron Obstruct Pulmon DisOct 1, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

The predictive value of early-pregnancy mean platelet volume for preeclampsia: A meta-analysis.

This meta-analysis assessed whether mean platelet volume (MPV) measured before 20 weeks’ gestation is associated with subsequent preeclampsia.

Acta Obstet Gynecol ScandOct 1, 2026Read summary
Clinical ResearchHematology

Phase 1 dose escalation and expansion trial of the bispecific CD47 inhibitor and CD40 agonist Fc-fusion protein SL-172154 (SIRPα-Fc-CD40L) in patients with higher-risk myelodysplastic syndrome or acute myeloid leukemia.

This Phase I clinical trial evaluated the safety and efficacy of the bispecific CD47 inhibitor SL-172154 combined with azacitidine (AZA) in patients with higher-risk myelodysplastic syndrome (HR-MDS) or acute myeloid…

CancerOct 1, 2026Read summary
Case ReportMedical Genetics

Variants in CEP135 Cause Congenital Microcephaly and Primary Ciliary Dyskinesia.

Three children from two families presented with congenital microcephaly and chronic respiratory issues consistent with primary ciliary dyskinesia (PCD). Diagnostic testing revealed autosomal recessive variants in CEP135.

Pediatr PulmonolOct 1, 2026Read case
Clinical ResearchNeurology

TMS-Derived Neurophysiological Measures of Corticospinal Excitability, Intracortical Excitability, and Interhemispheric Interactions Associated With Post-Stroke Motor Recovery: A Systematic Review.

This systematic review evaluated the relationship between TMS-derived neurophysiological measures and motor recovery in adults post-stroke, synthesizing data from 16 randomized controlled trials.

Eur J NeurosciOct 1, 2026Read summary
Case ReportNephrology

Resistant Hypertension Secondary to Renal Arteriovenous Malformation: A Case of Cure After Nephrectomy.

A 33-year-old woman with longstanding uncontrolled hypertension requiring five antihypertensive agents was evaluated for refractory blood pressure control.

Am J Case RepOct 1, 2026Read case
Clinical ResearchPulmonology

Davos@home: Integrating objective home monitoring into eHealth self-management support after alpine altitude climate treatment for severe asthma.

This 12-month pragmatic randomised trial assessed whether objective home monitoring adds benefit to eHealth self-management after Alpine Altitude Climate Treatment (AACT) in adults with severe asthma.

Respir MedOct 1, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Avutometinib, Abemaciclib, and Fulvestrant in Patients with HR+/HER2- Metastatic Breast Cancer Previously Treated with CDK4/6 Inhibitor: A Single-Arm Phase I Trial.

This single-arm phase I trial evaluated the combination of avutometinib, abemaciclib, and fulvestrant in 16 patients with HR+/HER2- metastatic breast cancer who had previously progressed on CDK4/6 inhibitors.

Clin Cancer ResOct 1, 2026Read summary
Case ReportOphthalmology

Identification of Variants in Two Families With Congenital Cataract by Whole Exome Sequencing.

Congenital cataract (CC) is an ophthalmic disorder diagnosed at birth or during early infancy, characterized by severe visual impairment and potential blindness.

Mol Genet Genomic MedOct 1, 2026Read case
Case ReportMedical Genetics

A Novel De Novo MTM1 Insertion Frameshift Variant Causes X-Linked Myotubular Myopathy in a Chinese Female.

A 24-year-old woman presented with infantile hypotonia and progressive, asymmetric proximal weakness, including facial and ocular involvement.

Mol Genet Genomic MedOct 1, 2026Read case
Case ReportMedical Genetics

A Novel BORCS5 Loss-Of-Function Variant in a Patient With a Rare Neurodevelopmental Disorder.

The BORCS5 is an important and critical component of the BLOC-one-related complex (BORC), involved in kinesin-dependent anterograde lysosomal transport.

Int J Dev NeurosciOct 1, 2026Read case

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