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1998 articles
October 202624
Clinical trial: The Effect on Intragastric pH and Pharmacokinetics of the PCAB Linaprazan Glurate in Healthy Subjects After Repeat-Dose Administration for up to 14 Days.
This open, randomised, parallel-group Phase 1 trial assessed intragastric pH and pharmacokinetics after single and repeated linaprazan glurate (LG) dosing in 73 healthy subjects.
"Ropi"-Thorax as a Complication of Landmark-Based Paravertebral Pain Catheter Placement: A Case Report.
A 42-year-old female with multiple rib fractures and a hemopneumothorax underwent landmark-guided placement of a paravertebral catheter for analgesia due to obstructed ultrasound visualization.
Pulsed Dye Laser for Sensory Dysesthesias Associated With Chronic Radiation Dermatitis.
Two breast cancer patients with chronic radiation dermatitis (CRD) presented with debilitating sensory dysesthesias unresponsive to conventional treatments.
Biologics and Small-Molecule Inhibitors for the Treatment of Nummular Eczema: A Systematic Review.
This systematic review evaluated the efficacy of biologics and small-molecule inhibitors for treating nummular eczema (NE) by analyzing 10 studies.
Cicatricial Ectropion in the Setting of IL-13 Inhibition.
An 81-year-old man with extensive atopic dermatitis was treated with dupilumab, leading to significant improvement. However, he later developed ocular symptoms and inferior cicatricial ectropion of the left lower eyelid.
Exceptional and Durable Response to Selpercatinib in a Patient with Apparently RET -Negative, HRAS -, and NF1 -Mutated Metastatic Medullary Thyroid Carcinoma.
A 50-year-old woman presented with rapidly progressive medullary thyroid carcinoma (Ki-67 30%) and extensive liver and bone metastases.
INDIVIDUAL ARTICLE: Tildrakizumab for Real-World Psoriasis Care: Clinical Lessons From Medically Complex and Underserved Patient Populations.
This case review discusses 16 patients with moderate-to-severe plaque psoriasis treated with tildrakizumab, a monoclonal antibody targeting interleukin-23.
Pediatric Literacy Promotion for Latino Families by Texts and Referrals: A 3-Arm RCT.
This randomized controlled trial evaluated two strategies to enhance literacy promotion among 630 Latino caregiver-infant dyads.
Meta-analysis of Asymptomatic Monkeypox Virus Prevalence in Nonendemic Regions, 2022-2024.
This meta-analysis examined the prevalence of asymptomatic monkeypox virus (MPXV) detections in nonendemic regions from May 2022 to September 2024.
Meta-analysis of Maternal and Fetal Outcomes of Crimean-Congo Hemorrhagic Fever during Pregnancy.
This meta-analysis examined the maternal and fetal outcomes of Crimean-Congo hemorrhagic fever (CCHF) in 55 pregnancies. The study found a maternal mortality rate of 28.8% and a fetal loss rate of 57.4%.
HIV-associated pulmonary arterial hypertension: improving survival despite persistent treatment gaps - a systematic review and meta-analysis.
This systematic review and meta-analysis examined 12 cohorts of patients with HIV-associated pulmonary arterial hypertension (HIV-PAH), totaling 537 individuals.
A Systematic Review and Meta-Analysis of the Prevention and Management of Pediatric Urinary Tract Infection and Suspected Urinary Tract Infection: Technical Report.
This systematic review and meta-analysis evaluated management strategies for pediatric urinary tract infections (UTIs) in children without known anatomic anomalies, including antibiotic duration and route, and the use…
Tumor-Infiltrating Lymphocytes as a Predictor of Adjuvant Avelumab Efficacy in Patients with High-risk Triple-Negative Breast Cancer.
This phase III randomized controlled trial investigated the prognostic and predictive value of tumor-infiltrating lymphocytes (TIL) in 466 patients with high-risk early triple-negative breast cancer (TNBC) receiving…
Clinical Trial Protocol for LPS-Boost: Intensified [ 177 Lu]Lu-PSMA-617 Treatment for Patients with Metastatic Castration-Resistant Prostate Cancer with Low PSMA-Expressing Disease.
This multicenter, open-label phase 2 trial investigates an intensified treatment schedule of [177Lu]Lu-PSMA-617 for 45 patients with metastatic castration-resistant prostate cancer (mCRPC) and low PSMA expression.
Effects of Estriol-Lactobacilli Combination Versus Polycarbophil-Based Vaginal Moisturizer on Post-Radiation Vaginitis in Women With Cervical Cancer: A Randomized Controlled Trial.
This randomized controlled trial evaluated the efficacy of an estriol-lactobacilli combination vaginal tablet (E3/L) versus a polycarbophil-based vaginal moisturizer (PBVM) in 34 women with post-radiation vaginitis…
Prednisone in the Management of Pericarditis: A Systematic Review.
This systematic review evaluated the use of oral corticosteroids, primarily prednisone, in adults with acute or recurrent pericarditis.
Tumor and Organ Dose Estimates from 177 Lu-PSMA-617 Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer: Results from the RESIST-PC Phase 2 Trial.
The RESIST-PC Phase 2 trial assessed dosimetry of [177Lu]Lu-PSMA-617 in patients with metastatic castration-resistant prostate cancer. A total of 48 patients were analyzed, receiving either 6.0 or 7.4 GBq per cycle.
"I Don't Speak English Well." Do Language Barriers Affect Automated External Defibrillator Use? A Randomized Simulation Study With Spanish-Speaking Laypeople.
This randomized controlled trial assessed the impact of language barriers on automated external defibrillator (AED) use among 50 Spanish-speaking university students.
Systematic Review and Meta-Analysis on Rescue Stenting for Large Vessel Occlusion Due to Underlying Intracranial Atherosclerotic Stenosis.
This systematic review and meta-analysis evaluated the efficacy and safety of rescue stent placement in patients with large vessel occlusion (LVO) due to intracranial atherosclerotic stenosis (ICAS).
Cost-Effectiveness of Adjunctive Middle Meningeal Artery Embolization for Chronic Subdural Hematoma: Secondary Analysis of EMBOLISE.
This secondary analysis of the EMBOLISE randomized trial evaluated the cost-effectiveness of adjunctive middle meningeal artery embolization (MMAE) versus evacuation surgery (ES) alone in 42 patients with chronic…
Volumetric Postcontrast T1 Turbo Spin-Echo vs Gradient-Recalled Echo MR Sequences for Detecting Brain Metastases: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the diagnostic performance of postcontrast 3D T1 Turbo Spin-Echo (TSE) versus Gradient-Recalled Echo (GRE) MRI sequences for detecting brain metastases in 544 patients.
Management of Antineutrophil Cytoplasmic Antibody-Associated Alveolar Hemorrhage: A Bayesian Reanalysis of the PEXIVAS Trial.
This Bayesian reanalysis of the PEXIVAS trial focused on adults with antineutrophil cytoplasmic antibody-associated vasculitis and diffuse alveolar hemorrhage (DAH).
Temporal Net Water Uptake Evolution and Its Association with Functional Outcome in Acute Ischemic Stroke.
This multicenter randomized controlled trial examined the relationship between temporal changes in net water uptake (NWU) and functional outcomes in 115 patients with acute ischemic stroke.
Evaluating CPR Breast Attachment Impact on EMT Training: A Randomized Controlled Trial.
This randomized controlled trial evaluated the impact of the ReviveHer breast attachment on EMT students' willingness and comfort in performing CPR on breasted and nonbreasted individuals.
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