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1998 articles
October 202624
Long-Term Quantitative MRI and Quality-of-Life After Endovascular Therapy in Acute Ischemic Stroke - A MR CLEAN-NO IV Substudy.
This long-term substudy of the MR CLEAN-NO IV randomised trial examined quantitative MRI and quality of life three years after acute ischaemic stroke.
Atypical presacral masses in Currarino syndrome: a case series.
The report describes three patients with Currarino syndrome, a congenital condition involving a sacral anomaly, anorectal malformation, and presacral mass.
Fibro-Inflammatory Signaling, Fibrosis, and Microvascular Ischemia as Convergent Translational Substrates of Sudden Cardiac Death in Hypertrophic Cardiomyopathy: A Systematic Review.
This systematic translational review examined whether fibro-inflammatory signaling, fibrosis, and microvascular ischemia converge as substrates for ventricular arrhythmia and sudden cardiac death in hypertrophic…
Factors associated with 1-year health-related quality of life after neck-specific exercise in chronic whiplash-associated disorders: an exploratory secondary analysis of a randomized controlled trial.
This exploratory secondary analysis of a prospective, assessor-blinded, multicentre randomised trial examined factors associated with health-related quality of life (HRQoL) after neck-specific exercise in 140 people…
Successful management of long-term venovenous ECMO for severe PARDS in a child with acute lymphoblastic leukemia.
A 5-year-old boy with low-risk B-cell acute lymphoblastic leukemia developed severe, refractory pediatric acute respiratory distress syndrome during induction therapy, with profound hypoxemia.
Premenstrual Syndrome and Premenstrual Dysphoric Disorder: A Systematic Review of Academic Performance and Well-Being in University Students.
This systematic review synthesized 11 observational, cross-sectional studies of female medical and health sciences students published between January 2014 and December 2024.
Clinical translation of polymeric microneedles for bioactive nanovesicle delivery in hypertrophic scar remodeling.
This prospective, single-center, open-label, single-arm study evaluated a 12-week protocol combining microplasma radiofrequency, poly(L-lactic acid) microneedles, and topical milk-derived bioactive nanovesicles in 26…
Myeloid neoplasm with PDGFRA rearrangement presenting in blast-phase with basophilia.
An adult man from Southern Africa presented with progressive fatigue. Blood morphology showed marked basophilia and 21% myeloblasts, with flow cytometry supporting a provisional diagnosis of acute myeloid leukaemia with…
Refining Home-Based Squat Training: The Role of Hip Adduction in Improving Neuromuscular Control for Clinically Diagnosed Patellofemoral Pain Syndrome.
This randomized controlled trial compared an 8-week home-based squat program with and without hip adduction in 30 participants with clinically diagnosed patellofemoral pain syndrome (PFPS); both groups also performed…
Cost comparison of the ShangRing device versus Mogen clamp for early infant male circumcision in Sub-Saharan Africa.
This cost comparison alongside a randomized controlled trial assessed early infant male circumcision using the ShangRing (SR) versus the Mogen clamp (MoC) among infants aged 0–60 days in Kenya, Tanzania, and Uganda.
PTCD and Peroral Electronic Cholangioscopy with Holmium Laser Lithotripsy for CBD Stones in a Super-Elderly Patient Post-Billroth II Gastrojejunostomy.
The management of impacted common bile duct stones in patients with prior Billroth II gastrectomy poses unique challenges. Altered gastrointestinal anatomy renders duodenoscope passage and biliary cannulation during…
Early Discharge Strategy Including Subcutaneous Furosemide in Hospitalized Heart Failure.
This multicenter, open-label, randomized active-controlled trial in the United Kingdom studied 172 patients hospitalized with heart failure who still required parenteral diuretics.
Prevalence and genotype distribution of norovirus and rotavirus among children under five with diarrheal infection in lower-middle-income countries after Rotavirus vaccine introduction: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed norovirus and rotavirus prevalence and genotype distribution among children under five with diarrheal infection in low- and middle-income countries after rotavirus…
Machine Learning, Radiomics, and Clinical Models Predicting Checkpoint Inhibitor Pneumonitis in Lung Cancer: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis assessed machine-learning, radiomics, deep-learning, and clinical models for predicting checkpoint inhibitor pneumonitis in people with lung cancer.
Occlusion-Focused Triage vs Very-High-Risk NSTEMI Criteria: A DIFOCCULT-3 Substudy.
This substudy of the multicenter, cluster-randomized DIFOCCULT-3 trial compared occlusion/nonocclusion (OMI/NOMI) classification with the conventional STEMI/NSTEMI framework and guideline-defined very-high-risk NSTEMI…
Robot-assisted ileal ureter replacement for complex ureteral strictures: a systematic review and single-arm meta-analysis of surgical and functional outcomes.
This systematic review and single-arm meta-analysis assessed surgical and functional outcomes after robot-assisted ileal ureter replacement (RIUR) in adults with complex ureteral strictures.
Predicting IGD treatment outcomes across interventions using a whole-brain functional connectome biomarker.
This clinical trial study examined whether resting-state whole-brain functional connectivity could predict symptom improvement in 90 individuals with internet gaming disorder (IGD) receiving mindfulness meditation…
Blood pressure targets in adults with hypertension.
This publication is a protocol for a Cochrane intervention review, not a report of completed results. It sets out to assess lower blood pressure targets (≤ 135/85 mmHg) versus standard targets (≤ 140 to 160/90 to 100…
Home visits following hospital discharge for families with preterm and low-birthweight infants.
This Cochrane systematic review and meta-analysis assessed randomised trials of home visits after discharge for families of preterm or low-birthweight infants.
Continuous intrathecal therapy for refractory cancer pain: A systematic review and meta-analysis focusing on partially implanted devices.
This systematic review and meta-analysis assessed partially implanted intrathecal devices (PIDs) for adults with refractory cancer-related pain, comparing them with conventional medical management and, in comparative…
Extracting the Unexpected: A 35-mm Curved Nail as an Intraocular Foreign Body.
A 31-year-old man presented with left-eye pain and severe vision loss seven days after penetrating injury from a metallic object.
Effect of injectable platelet rich fibrin augmented with vitamin c compared to injectable platelet rich fibrin alone on healing of necrotic mature single rooted teeth with chronic periapical periodontitis following regenerative endodontic therapy (a randomized controlled trial).
This randomized controlled trial compared injectable platelet-rich fibrin (i-PRF) with and without vitamin C during regenerative endodontic treatment in 28 healthy patients with necrotic mature single-rooted teeth and…
Use of Instructional Therapeutic Play during the preoperative nursing consultation of a child with orofacial clefts.
An 8-year-old girl with an orofacial cleft was preparing for cleft palate repair and expressed fear and anxiety about surgery, especially that she might not wake up after anesthesia.
A case of renal hypouricemia type 1 associated with compound heterozygous URAT1/SLC22A12 variants A209V and F379L: clinical evidence for their pathogenic significance.
A 69-year-old woman was evaluated for renal dysfunction and hypouricemia. Testing showed serum uric acid of 0.7 mg/dL and a fractional urate clearance (Cua/Ccr) of 60.5%, alongside CKD stage G3b and a renal stone.
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