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1998 articles

October 202624

Clinical ResearchAnesthesiology

Assessing the completeness of safety reporting in clinical trials of regional anesthesia interventions: a registry-publication comparison systematic review.

This systematic review evaluated the completeness of adverse event (AE) reporting in interventional regional anesthesia trials registered on ClinicalTrials.gov and their corresponding publications.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchPlastic Surgery

Feeding following cleft palate surgery: a prospective randomized clinical trial comparing suprazygomatic maxillary nerve block and greater palatine nerve block.

This randomized controlled trial evaluated the effectiveness of suprazygomatic maxillary nerve blocks (SZMNB) versus greater palatine nerve blocks (GPNB) in children aged 1-10 undergoing cleft palate surgery.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchAnesthesiology

Clinical utility of randomized controlled trials of regional anesthesia for lower-extremity surgery: a systematic review.

This systematic review evaluated the clinical utility and transparency of randomized controlled trials (RCTs) on regional anesthesia (RA) for lower-extremity surgeries.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchNeurology

Objective, long-term mobility data in patients with chronic pain after lumbar spine surgery treated with spinal cord stimulation-a prospective, multicenter trial.

This multicenter clinical trial evaluated the long-term effects of spinal cord stimulation (SCS) on mobility in 50 patients with chronic pain following lumbar spine surgery.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchUrology

Caudal versus penile block and urethrocutaneous fistula formation following hypospadias repair in children <2 years: a multicenter randomized clinical trial.

This multicenter randomized controlled trial evaluated the incidence of urethrocutaneous fistula (UCF) formation in children under 2 years undergoing hypospadias repair with either caudal or penile block.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchGastroenterology

Efficacy of Bifidobacterium animalis subsp. lactate BL-99 in relieving functional constipation: a randomized placebo-controlled clinical trial.

This randomized, double-blind, placebo-controlled trial evaluated the efficacy of Bifidobacterium animalis subsp. lactis BL-99 in 41 patients with functional constipation over 6 weeks.

Food FunctOct 5, 2026Read summary
Clinical ResearchEmergency Medicine

Comparative Ultrasound Assessment of Standard and Wire-Core Airway Bougie Introducers in a Cadaver Model.

This randomized controlled trial evaluated the accuracy of point-of-care ultrasound (POCUS) in identifying standard bougie (SB) versus wire-core bougie (WCB) placements in cadaver models.

J Spec Oper MedOct 5, 2026Read summary
Clinical ResearchOncology (Medical)

A study on the intervention effect of a structured grief counseling program on grief responses in family caregivers of patients with advanced cancer.

This randomized controlled trial evaluated the impact of structured grief counseling on grief responses in family caregivers of advanced cancer patients.

Palliat Support CareOct 5, 2026Read summary
Clinical ResearchMedical GeneticsOpen access

A nationwide prospective randomized trial for diagnosing developmental disorders demonstrates genome sequencing outperforms standard of care.

This nationwide prospective randomized trial evaluated the diagnostic efficacy of genome sequencing (GS) compared to standard of care (SoC) in 567 individuals with unexplained developmental disorders (DD).

Genome MedOct 5, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Fluid balance during hot-dry and warm-humid heat stress while adhering to occupational hydration recommendations.

This randomized controlled trial assessed fluid balance in 20 healthy adults during moderate-intensity work in hot-dry (HD) and warm-humid (WH) environments while following NIOSH hydration recommendations.

Ann Work Expo HealthOct 5, 2026Read summary
Clinical ResearchNeurologyOpen access

Electroacupuncture Targeting the NLRP3 Inflammasome in Senescence‑associated Cognitive Impairment: Mechanistic Synthesis and Meta‑analysis of Clinical Randomized Controlled Trials.

This meta-analysis reviewed nine randomized controlled trials involving 614 participants to evaluate the effects of electroacupuncture on senescence-associated cognitive impairment (SACI).

Neurochem ResOct 5, 2026Read summary
Clinical ResearchEndocrinology

Effects of rosehip (Rosa canina) supplementation on orthostatic intolerance symptoms in patients with type 2 diabetes: a randomized double-blind placebo-controlled clinical trial.

This randomized double-blind placebo-controlled trial investigated the effects of rosehip fruit extract on orthostatic intolerance symptoms in 60 adults with type 2 diabetes and orthostatic hypotension.

DaruOct 5, 2026Read summary
Clinical ResearchUrologyOpen access

Lymphocele After Radical Prostatectomy: A Systematic Review of Risk Factors and Quantitative Synthesis Preventive Strategies.

This systematic review evaluated risk factors and preventive strategies for lymphocele formation after radical prostatectomy with pelvic lymph node dissection.

World J UrolOct 5, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Morphometric findings of the subaxial cervical spine among different geographic regions and the implications for cervical pedicle screw placement: a systematic review and meta-analysis.

This systematic review and meta-analysis examined cervical pedicle dimensions and insertion angles across diverse populations, analyzing data from 4014 patients across 18 countries.

Neurosurg RevOct 5, 2026Read summary
Case ReportEmergency Medicine

Ultrasound-Guided Disposition: Submersion Injury.

A 25-year-old male sustained an acute submersion injury due to water aspiration during snorkel training for U.S. Navy Search and Rescue Swimmer training.

J Spec Oper MedOct 5, 2026Read case
Case ReportNephrologyOpen access

Nephrotic range proteinuria and rapid progression to end-stage kidney disease in seronegative pauci-immune necrotizing glomerulonephritis masked by cutaneous lesions: a case-based review.

A 22-year-old woman with a history of recurrent cutaneous lesions was hospitalized due to exacerbation of her skin condition. Laboratory tests revealed nephrotic-range proteinuria and reduced eGFR.

Rheumatol IntOct 5, 2026Read case
Clinical ResearchInfectious Diseases

Geographical and temporal patterns of cutaneous leishmaniasis in Pakistan: insight from a decade of epidemiology.

This systematic review examined the geographical distribution and epidemiological trends of cutaneous leishmaniasis (CL) in Pakistan from 2014 to 2024.

Trans R Soc Trop Med HygOct 5, 2026Read summary
Clinical ResearchInfectious Diseases

Temporal proximity to counseling is associated with longitudinal bedaquiline and antiretroviral therapy adherence in multidrug-resistant tuberculosis and HIV treatment.

This randomized controlled trial examined the relationship between counseling session timing and medication adherence in 76 participants receiving treatment for multidrug-resistant tuberculosis (MDR-TB) and HIV in South…

PLoS OneOct 5, 2026Read summary
Clinical ResearchPsychiatry

A Problem-Solving Therapy With Apple Watch Support for College Students With Alcohol Use Disorder Symptoms: Pilot Randomized Controlled Trial.

This pilot randomized controlled trial evaluated the feasibility and preliminary effectiveness of a problem-solving therapy supported by Apple Watch (PST-APPLE) for college students with alcohol use disorder (AUD)…

JMIR Form ResOct 5, 2026Read summary
Clinical ResearchPediatrics

Serum ferritin in children with Attention Deficit Hyperactivity Disorder (ADHD): A systematic review and meta-analysis.

This systematic review and meta-analysis examined serum ferritin levels in children with Attention Deficit Hyperactivity Disorder (ADHD) compared to healthy controls.

PLoS OneOct 5, 2026Read summary
Case ReportOtolaryngology (ENT)

Treatment of External Auditory Canal Hemangioma by Surgical Excision and Flap Reconstruction: 2 Case Reports.

Two cases of external auditory canal (EAC) hemangiomas are reported. The first case involved a 68-year-old man with a sensation of fullness in the left ear, while the second case involved a 62-year-old woman with…

Am J Case RepOct 5, 2026Read case
Clinical ResearchCardiologyOpen access

Effects of Benzodiazepines on Heart Failure Outcomes and Adverse Events: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the impact of benzodiazepines (BZDs) on heart failure (HF) outcomes in high-risk populations.

Cardiovasc ToxicolOct 5, 2026Read summary
Clinical ResearchGastroenterology

Follow-up colonoscopy after abnormal stool-based colorectal cancer screening: a systematic review of completion, timeliness and implementation strategies.

This systematic review examined the completion rates and timeliness of diagnostic colonoscopy following abnormal stool-based colorectal cancer screenings in adults.

BMJ OpenOct 5, 2026Read summary
Clinical ResearchMedical Genetics

PHOENIX: a study protocol for a pilot randomised controlled trial of pre-emptive pharmacogenomic panel testing in acute care settings with health economic evaluations.

The PHOENIX trial is a pilot randomized controlled trial assessing the impact of pre-emptive pharmacogenomic panel testing on adverse drug reactions (ADRs) and treatment failures in acute care settings.

BMJ OpenOct 5, 2026Read summary

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