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1999 articles

September 202624

Clinical ResearchMedical Genetics

Efficacy and safety of garetosmab, an activin A-blocking antibody, in fibrodysplasia ossificans progressiva (OPTIMA): a randomised, double-blind, placebo-controlled, phase 3 trial.

OPTIMA was a multicentre, randomised, double-blind, placebo-controlled phase 3 trial assessing monthly intravenous garetosmab in adults with fibrodysplasia ossificans progressiva.

LancetSep 28, 2026Read summary
Clinical ResearchPediatrics

Adherence to the Mediterranean Diet Is Associated With a Lower Risk of Obesity in Children Under 18 Years: A Comprehensive Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined the relationship between adherence to the Mediterranean Diet (MedDiet) and obesity risk in children and adolescents.

Pediatr ObesSep 28, 2026Read summary
Case ReportPathology (Anatomic & Clinical)

Primary renal glomus tumours of uncertain malignant potential: diagnostic challenges and insights from two instances.

Two elderly patients presented with abdominal pain and were found to have large renal masses on imaging. Both underwent nephrectomy, and histopathological analysis revealed glomus tumors with atypical features but not…

BMJ Case RepSep 28, 2026Read case
Clinical ResearchNephrology

Effectiveness and Safety of Virtual Reality Interventions for Symptom Management in Adults Undergoing Hemodialysis: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis evaluated the effectiveness and safety of virtual reality (VR) interventions for symptom management in adults undergoing hemodialysis.

J Med Internet ResSep 28, 2026Read summary
Clinical ResearchUrology

Efficacy and safety of α1-adrenergic receptor antagonists in managing acute urinary retention secondary to benign prostatic hyperplasia: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the efficacy of α1-adrenergic receptor antagonists in managing acute urinary retention (AUR) due to benign prostatic hyperplasia (BPH).

Arch Ital Urol AndrolSep 28, 2026Read summary
Clinical ResearchOncology (Medical)Open access

A comparison of the efficacy of cognitive-behavioral stress management and acceptance and commitment therapy on the quality of life and fatigue of caregivers of patients with cancer: a randomized controlled trial.

This randomized controlled trial compared the efficacy of cognitive behavioral stress management (CBSM) and acceptance and commitment therapy (ACT) on the quality of life and fatigue in 66 caregivers of cancer patients.

Support Care CancerSep 28, 2026Read summary
Clinical ResearchPediatrics

Effects of Teleintervention Maintenance Programs for Children (Age 6-12) and Adolescents (Age 13-18) With Overweight or Obesity-Promoting a Healthy Lifestyle: A Systematic Review.

This systematic review evaluated teleintervention maintenance programs for children (ages 6-12) and adolescents (ages 13-18) with overweight or obesity.

Pediatr ObesSep 28, 2026Read summary
Case ReportCardiology

The "Spiked Helmet Sign" on Electrocardiogram Following Left Ventricular Assist Device Implantation: A Case Report.

A 68-year-old male with end-stage ischemic cardiomyopathy underwent left ventricular assist device (LVAD) implantation. Shortly after the procedure, his ECG displayed the 'Spiked Helmet Sign' alongside QTc prolongation.

Ann Noninvasive ElectrocardiolSep 27, 2026Read case
Clinical ResearchOncology (Medical)Open access

Mindful eating as a supportive intervention for breast cancer survivors: a pilot randomized controlled trial.

This pilot randomized controlled trial assessed whether a six-session mindful eating intervention added to treatment-as-usual (TAU) improved eating behaviors and body composition in breast cancer survivors.

Breast CancerSep 27, 2026Read summary
Clinical ResearchOncology (Medical)

External validation of the NADIR model for early prostate-specific antigen response prediction in enzalutamide-treated metastatic hormone-sensitive prostate cancer: An analysis of the ARCHES trial.

This validation study assessed the NADIR model's ability to predict early prostate-specific antigen (PSA) response in 558 enzalutamide-treated patients from the ARCHES trial.

CancerSep 27, 2026Read summary
Case ReportInfectious Diseases

Pulmonary Actinomycosis Diagnosed via BALF mNGS in a 53-Year-Old Nonsmoking Man With Pneumoconiosis and Penicillin-Induced Thrombocytopenia: A Case Report.

A 53-year-old nonsmoking man with pneumoconiosis presented with a month-long history of cough and hemoptysis. Imaging revealed bilateral upper-lung masses and lymphadenopathy, leading to a right upper lobectomy under…

Am J Case RepSep 27, 2026Read case
Clinical ResearchCardiology

Cost-effectiveness of heart failure pharmacotherapy withdrawal in recovered atrial fibrillation mediated cardiomyopathy: analysis of the WITHDRAW-AF randomized clinical trial.

This economic analysis of the WITHDRAW-AF randomized clinical trial compared heart failure pharmacotherapy withdrawal with continuation in carefully selected patients with recovered atrial fibrillation-mediated…

Int J CardiolSep 27, 2026Read summary
Case ReportMedical GeneticsOpen access

Phenotypic spectrum of 19p13.3 microdeletion: a fatal infant case with severe cardiomegaly and gastrointestinal manifestations.

An 8-month-old female infant presented with multisystemic complications, including congenital heart defects, limb anomalies, macrocephaly, and recurrent pulmonary infections.

Mol Biol RepSep 27, 2026Read case
Clinical ResearchNephrologyOpen access

Longitudinal impact of sodium bicarbonate therapy on health-related quality of life in pre-dialysis chronic kidney disease with metabolic acidosis: a pragmatic trial in Malaysia.

This pragmatic clinical trial evaluated the impact of sodium bicarbonate therapy on health-related quality of life (HRQoL) in 74 pre-dialysis chronic kidney disease (CKD) patients with metabolic acidosis over 18 months.

Qual Life ResSep 27, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Low-intensity pulsed ultrasound to facilitate uterine involution: prospective multicenter study on clinical efficacy and mechanistic insights.

This multicenter, randomized controlled trial evaluated the efficacy of low-intensity pulsed ultrasound (LIPUS) in promoting uterine involution post-delivery among 1,106 women.

Ultrasound Obstet GynecolSep 27, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Determinants of preterm pre-eclampsia following low-dose aspirin prophylaxis: evidence from stepped-wedge cluster randomized trial in Asia.

This multicenter stepped-wedge cluster randomized trial studied 2919 high-risk pregnant women receiving low-dose aspirin prophylaxis to identify risk factors for preterm pre-eclampsia (PE).

Ultrasound Obstet GynecolSep 27, 2026Read summary
Case ReportOphthalmology

Functional Improvement with Red-Tinted Contact Lens in Pediatric Achromatopsia: A Case Report.

A child with achromatopsia presented with reduced visual acuity, photophobia, and impaired color discrimination. Following the fitting of red-tinted contact lenses, the patient reported significant improvements in glare…

Eye Contact LensSep 26, 2026Read case
Case ReportGastroenterology

Phlegmonous Gastritis Refractory to Antibiotics with Subsequent Improvement on Empiric Quadruple Therapy.

A 59-year-old woman presented with two days of severe nausea, vomiting, and inability to tolerate oral intake while on chronic proton-pump inhibitor therapy.

R I Med J (2013)Sep 26, 2026Read case
Clinical ResearchGeriatrics

Effect of Multi-Modal Training in Patients With Mild Cognitive Impairment: A Randomized Controlled Pilot Trial.

This pilot randomized controlled trial evaluated the effects of a 24-week multi-modal training program on cognitive function in 65 older adults with mild cognitive impairment (MCI).

Med Sci MonitSep 26, 2026Read summary
Clinical ResearchUrologyOpen access

Exploring the impact of artificial intelligence on radiation dose reduction in urological imaging: a systematic review from EAU endourology.

This systematic review evaluated the impact of artificial intelligence (AI) on radiation dose reduction in urological CT imaging.

World J UrolSep 26, 2026Read summary
Case ReportOncology (Medical)Open access

Concurrent follicular lymphoma and follicular dendritic cell sarcoma: composite neoplasm or transdifferentiation?

A 52-year-old woman presented with night sweats, weight loss, and an obstructing colonic mass with mesenteric disease. Biopsy revealed two distinct tumor populations: one consistent with follicular large B cell lymphoma…

J HematopSep 26, 2026Read case
Case ReportHematology

When A Fall Isn't Just a Fall: Delayed Diagnosis of Acquired Hemophilia A in a Nonagenarian Patient.

A 92-year-old woman presented with severe right lower extremity pain after recurrent ground-level falls. Imaging revealed bilateral lower extremity intramuscular hematomas.

Am J Case RepSep 26, 2026Read case
Clinical ResearchOncology (Medical)Open access

Virtual reality as a non-pharmacological adjuvant for anxiety in oncology care: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of virtual reality (VR) interventions for managing anxiety in cancer patients.

Support Care CancerSep 26, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Help-seeking behavior and its determinants among gender-based violence survivor women in Africa: A systematic review and meta-analysis.

This systematic review and random-effects meta-analysis estimated help-seeking among women who had experienced gender-based violence in Africa and examined associated factors.

Soc Sci MedSep 26, 2026Read summary

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