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1998 articles

October 202624

Clinical ResearchOncology (Medical)Open access

Application of a concise video to improve patient understanding of tumor genomic testing in community and academic practice settings.

This multicenter clinical trial evaluated a 3–4 minute educational video for patients undergoing standard-of-care tumor genomic testing (TGT), across cancer types and academic and community settings.

PLoS OneOct 13, 2026Read summary
Case ReportNeurosurgery

Stroke thrombectomy of a mural thrombus in a severe dolichoectatic basilar artery with double parallel large stent retrievers and Sofia 88.

An older adult presented with severe acute ischemic stroke from a mural thrombus on the posterior wall of the mid-basilar artery.

J Neurointerv SurgOct 13, 2026Read case
Clinical ResearchDermatology

Clinical translation of polymeric microneedles for bioactive nanovesicle delivery in hypertrophic scar remodeling.

This prospective, single-center, open-label, single-arm study evaluated a 12-week protocol combining microplasma radiofrequency, poly(L-lactic acid) microneedles, and topical milk-derived bioactive nanovesicles in 26…

Biomater SciOct 13, 2026Read summary
Clinical ResearchPediatricsOpen access

Daily Zinc Supplementation for Infection Prevention in Children With Sickle Cell Anemia: The ZIPS-2 Randomized Clinical Trial.

The ZIPS-2 randomized, double-blind, placebo-controlled trial evaluated daily zinc for infection prevention in children aged 1 to 4.99 years with sickle cell anemia in Uganda.

JAMAOct 13, 2026Read summary
Case ReportNeurologyOpen access

Clinicopathologic Evaluation of Amyloid Clearance in Alzheimer Disease.

A man in his 50s with mild cognitive impairment and the Alzheimer disease risk-associated p.R47H TREM2 variant received 30 doses of aducanumab (cumulative dose 280 mg/kg) over 4.5 years in a clinical trial.

JAMAOct 13, 2026Read case
Clinical ResearchGastroenterology

Network Meta-Analysis: Treatments for Acute Alcohol-Associated Hepatitis.

This systematic review and network meta-analysis compared treatments for alcohol-associated hepatitis (AH) using 90-day survival as the primary outcome.

Liver IntOct 13, 2026Read summary
Clinical ResearchNeurology

Post-Stroke Depression and Determinants in Ethiopia; A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined the prevalence and determinants of post-stroke depression (PSD) in Ethiopia, combining findings from eight studies.

Int J Methods Psychiatr ResOct 13, 2026Read summary
Case ReportGastroenterology

PTCD and Peroral Electronic Cholangioscopy with Holmium Laser Lithotripsy for CBD Stones in a Super-Elderly Patient Post-Billroth II Gastrojejunostomy.

The management of impacted common bile duct stones in patients with prior Billroth II gastrectomy poses unique challenges. Altered gastrointestinal anatomy renders duodenoscope passage and biliary cannulation during…

J Vis ExpOct 13, 2026Read case
Clinical ResearchObstetrics & Gynecology

Premenstrual Syndrome and Premenstrual Dysphoric Disorder: A Systematic Review of Academic Performance and Well-Being in University Students.

This systematic review synthesized 11 observational, cross-sectional studies of female medical and health sciences students published between January 2014 and December 2024.

J Vis ExpOct 13, 2026Read summary
Case ReportHematologyOpen access

Myeloid neoplasm with PDGFRA rearrangement presenting in blast-phase with basophilia.

An adult man from Southern Africa presented with progressive fatigue. Blood morphology showed marked basophilia and 21% myeloblasts, with flow cytometry supporting a provisional diagnosis of acute myeloid leukaemia with…

J HematopOct 13, 2026Read case
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Factors associated with 1-year health-related quality of life after neck-specific exercise in chronic whiplash-associated disorders: an exploratory secondary analysis of a randomized controlled trial.

This exploratory secondary analysis of a prospective, assessor-blinded, multicentre randomised trial examined factors associated with health-related quality of life (HRQoL) after neck-specific exercise in 140 people…

BMC Musculoskelet DisordOct 13, 2026Read summary
Clinical ResearchNeurologyOpen access

Long-Term Quantitative MRI and Quality-of-Life After Endovascular Therapy in Acute Ischemic Stroke - A MR CLEAN-NO IV Substudy.

This long-term substudy of the MR CLEAN-NO IV randomised trial examined quantitative MRI and quality of life three years after acute ischaemic stroke.

Transl Stroke ResOct 13, 2026Read summary
Case ReportCardiology

Life-Threatening Ventricular Tachycardia and Transient Brugada-Like Electrocardiographic Abnormalities Caused by Severe Hyperkalemia Due to Urinary Retention in a 55-Year-Old Man.

A 55-year-old man without known cardiovascular disease presented with palpitations, dyspnea, and diaphoresis, then developed hemodynamically unstable sustained wide-QRS ventricular tachycardia with recurrent episodes…

Am J Case RepOct 13, 2026Read case
Clinical ResearchUrologyOpen access

Opioid-free versus opioid-based anesthesia for robot-assisted radical prostatectomy: a single-center randomized controlled trial.

This single-center randomized controlled trial compared opioid-free anesthesia (dexmedetomidine plus ketamine) with remifentanil-based anesthesia in adult men undergoing robot-assisted radical prostatectomy.

J Robot SurgOct 13, 2026Read summary
Clinical ResearchNephrology

Haemodiafiltration, haemofiltration and haemodialysis for adults with kidney failure.

This Cochrane systematic review and meta-analysis assessed randomised trials comparing convective dialysis (haemofiltration, haemodiafiltration or acetate-free biofiltration) with diffusive haemodialysis or expanded…

Cochrane Database Syst RevOct 13, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Refining Home-Based Squat Training: The Role of Hip Adduction in Improving Neuromuscular Control for Clinically Diagnosed Patellofemoral Pain Syndrome.

This randomized controlled trial compared an 8-week home-based squat program with and without hip adduction in 30 participants with clinically diagnosed patellofemoral pain syndrome (PFPS); both groups also performed…

Med Sci MonitOct 13, 2026Read summary
Case ReportPhysical Medicine & RehabilitationOpen access

Integrated physical, cognitive and psychological rehabilitation following multiple ACL reconstructions in a professional handball player: a case report.

A 31-year-old professional handball player with two ACL reconstructions, meniscal repairs, a postoperative knee infection, and multiple arthroscopic procedures had persistent knee instability, pain, and psychological…

J Med Case RepOct 13, 2026Read case
Clinical ResearchCardiology

Effect of diet-induced plasma ceramide on human in vivo microvascular endothelial function.

This double-blind, randomized crossover trial examined whether a meal-induced rise in plasma ceramides impairs in vivo microvascular function in 23 healthy young adults.

Am J Physiol Heart Circ PhysiolOct 13, 2026Read summary
Clinical ResearchPsychiatry

Predicting IGD treatment outcomes across interventions using a whole-brain functional connectome biomarker.

This clinical trial study examined whether resting-state whole-brain functional connectivity could predict symptom improvement in 90 individuals with internet gaming disorder (IGD) receiving mindfulness meditation…

Dialogues Clin NeurosciOct 12, 2026Read summary
Case ReportGastroenterologyOpen access

Multifactorial Contributors to Diagnostic Delay in a High-Risk Patient with Hepatocellular Carcinoma: A Case Report with Clinical Lessons.

A 45-year-old Chinese man with chronic hepatitis B, type 2 diabetes, and a family history of primary liver cancer (PLC) was at high risk but had no regular PLC surveillance for three years.

Int Med Case Rep JOct 12, 2026Read case
Clinical ResearchOncology (Medical)Open access

Stereotactic body radiotherapy versus conventional external beam radiotherapy for bone metastases: a meta-analysis.

This systematic review and meta-analysis compared stereotactic body radiotherapy (SBRT) with conventional external beam radiotherapy (cEBRT) for painful bone metastases, pooling comparative clinical studies using…

Clin Exp MetastasisOct 12, 2026Read summary
Clinical ResearchUrologyOpen access

Comparative perioperative outcomes of Hugo™ RAS versus laparoscopic and Da Vinci platforms for partial nephrectomy: a systematic review and meta-analysis.

This systematic review and meta-analysis compared Hugo™ RAS with da Vinci-assisted and laparoscopic partial nephrectomy. It included four observational cohort studies comprising 383 patients.

J Robot SurgOct 12, 2026Read summary
Case ReportOphthalmology

Extracting the Unexpected: A 35-mm Curved Nail as an Intraocular Foreign Body.

A 31-year-old man presented with left-eye pain and severe vision loss seven days after penetrating injury from a metallic object.

Am J Case RepOct 12, 2026Read case
Clinical ResearchEndocrinologyOpen access

Effect of injectable platelet rich fibrin augmented with vitamin c compared to injectable platelet rich fibrin alone on healing of necrotic mature single rooted teeth with chronic periapical periodontitis following regenerative endodontic therapy (a randomized controlled trial).

This randomized controlled trial compared injectable platelet-rich fibrin (i-PRF) with and without vitamin C during regenerative endodontic treatment in 28 healthy patients with necrotic mature single-rooted teeth and…

BMC Oral HealthOct 12, 2026Read summary

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