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2000 articles

October 202624

Clinical ResearchInfectious Diseases

The dual burden of disease: Depression among patients with multidrug resistance tuberculosis in low-income and lower- middle-income countries: A systematic review and meta-analysis.

This systematic review and random-effects meta-analysis estimated depression prevalence and examined associated factors among patients with multidrug-resistant tuberculosis (MDR-TB) in low- and lower-middle-income…

PLoS OneOct 13, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Factors associated with 1-year health-related quality of life after neck-specific exercise in chronic whiplash-associated disorders: an exploratory secondary analysis of a randomized controlled trial.

This exploratory secondary analysis of a prospective, assessor-blinded, multicentre randomised trial examined factors associated with health-related quality of life (HRQoL) after neck-specific exercise in 140 people…

BMC Musculoskelet DisordOct 13, 2026Read summary
Clinical ResearchNeurologyOpen access

Pharmacological and Non-Pharmacological approaches to manage Tension-Type Headache: a Systematic Review.

This systematic review assessed randomized clinical trials of pharmacological and non-pharmacological treatments for episodic or chronic tension-type headache (TTH), examining headache pain and related clinical…

Curr Pain Headache RepOct 13, 2026Read summary
Clinical ResearchOphthalmology

USB-powered vs. self-heating warm compresses for meibomian gland dysfunction: A prospective randomized crossover clinical trial.

This prospective randomized crossover trial compared USB-powered and self-heating warm compresses in 15 adults aged 18–40 years with meibomian gland dysfunction and tear break-up time ≤10 s.

PLoS OneOct 13, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Application of a concise video to improve patient understanding of tumor genomic testing in community and academic practice settings.

This multicenter clinical trial evaluated a 3–4 minute educational video for patients undergoing standard-of-care tumor genomic testing (TGT), across cancer types and academic and community settings.

PLoS OneOct 13, 2026Read summary
Case ReportHematologyOpen access

Myeloid neoplasm with PDGFRA rearrangement presenting in blast-phase with basophilia.

An adult man from Southern Africa presented with progressive fatigue. Blood morphology showed marked basophilia and 21% myeloblasts, with flow cytometry supporting a provisional diagnosis of acute myeloid leukaemia with…

J HematopOct 13, 2026Read case
Clinical ResearchCardiology

Early Discharge Strategy Including Subcutaneous Furosemide in Hospitalized Heart Failure.

This multicenter, open-label, randomized active-controlled trial in the United Kingdom studied 172 patients hospitalized with heart failure who still required parenteral diuretics.

J Am Coll CardiolOct 13, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Premenstrual Syndrome and Premenstrual Dysphoric Disorder: A Systematic Review of Academic Performance and Well-Being in University Students.

This systematic review synthesized 11 observational, cross-sectional studies of female medical and health sciences students published between January 2014 and December 2024.

J Vis ExpOct 13, 2026Read summary
Clinical ResearchUrologyOpen access

Robot-assisted ileal ureter replacement for complex ureteral strictures: a systematic review and single-arm meta-analysis of surgical and functional outcomes.

This systematic review and single-arm meta-analysis assessed surgical and functional outcomes after robot-assisted ileal ureter replacement (RIUR) in adults with complex ureteral strictures.

J Robot SurgOct 12, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Dynamics and functional heterogeneity of FOXP3+ regulatory T cells in Trypanosoma cruzi infection: a systematic review.

This systematic review synthesised 27 studies of FOXP3+ regulatory T-cell (Treg) phenotype and function in human and experimental Trypanosoma cruzi infection: 9 human studies and 18 murine studies.

Inflamm ResOct 12, 2026Read summary
Clinical ResearchPsychiatry

Predicting IGD treatment outcomes across interventions using a whole-brain functional connectome biomarker.

This clinical trial study examined whether resting-state whole-brain functional connectivity could predict symptom improvement in 90 individuals with internet gaming disorder (IGD) receiving mindfulness meditation…

Dialogues Clin NeurosciOct 12, 2026Read summary
Clinical ResearchNeurologyOpen access

Next-generation pharmacological strategies for Parkinson's disease: a systematic literature review of symptom management and disease modification.

This PRISMA 2020 systematic literature review assessed pharmacological and emerging therapeutic strategies for symptom management and disease modification in Parkinson disease.

Neurol SciOct 12, 2026Read summary
Clinical ResearchPlastic SurgeryOpen access

Anatomical variation in the cervical branch of the facial nerve: a systematic review.

There is a paucity of literature on the anatomical variations of the cervical branch of the facial nerve (CBFN). Poor awareness of its anatomy and variations risks intraoperative damage, misdiagnosis of facial nerve…

Surg Radiol AnatOct 12, 2026Read summary
Case ReportNephrologyOpen access

Early-onset autosomal dominant distal renal tubular acidosis caused by a de novo SLC4A1 R589C variant with growth failure and rickets.

A Japanese boy had marked growth failure from 6 months of age and was diagnosed with autosomal dominant distal renal tubular acidosis at 27 months.

CEN Case RepOct 12, 2026Read case
Clinical ResearchOncology (Medical)Open access

Stereotactic body radiotherapy versus conventional external beam radiotherapy for bone metastases: a meta-analysis.

This systematic review and meta-analysis compared stereotactic body radiotherapy (SBRT) with conventional external beam radiotherapy (cEBRT) for painful bone metastases, pooling comparative clinical studies using…

Clin Exp MetastasisOct 12, 2026Read summary
Case ReportNephrologyOpen access

Delayed eculizumab therapy guided by markedly elevated soluble C5b-9 in a child with dialysis-requiring acute poststreptococcal glomerulonephritis: a case report.

A 9-year-old girl developed gross haematuria, oliguria and stage 3 acute kidney injury after an illness with vomiting and abdominal pain.

CEN Case RepOct 12, 2026Read case
Clinical ResearchUrologyOpen access

Comparative perioperative outcomes of Hugo™ RAS versus laparoscopic and Da Vinci platforms for partial nephrectomy: a systematic review and meta-analysis.

This systematic review and meta-analysis compared Hugo™ RAS with da Vinci-assisted and laparoscopic partial nephrectomy. It included four observational cohort studies comprising 383 patients.

J Robot SurgOct 12, 2026Read summary
Case ReportOphthalmology

Extracting the Unexpected: A 35-mm Curved Nail as an Intraocular Foreign Body.

A 31-year-old man presented with left-eye pain and severe vision loss seven days after penetrating injury from a metallic object.

Am J Case RepOct 12, 2026Read case
Clinical ResearchPediatrics

Home visits following hospital discharge for families with preterm and low-birthweight infants.

This Cochrane systematic review and meta-analysis assessed randomised trials of home visits after discharge for families of preterm or low-birthweight infants.

Cochrane Database Syst RevOct 12, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Effect of injectable platelet rich fibrin augmented with vitamin c compared to injectable platelet rich fibrin alone on healing of necrotic mature single rooted teeth with chronic periapical periodontitis following regenerative endodontic therapy (a randomized controlled trial).

This randomized controlled trial compared injectable platelet-rich fibrin (i-PRF) with and without vitamin C during regenerative endodontic treatment in 28 healthy patients with necrotic mature single-rooted teeth and…

BMC Oral HealthOct 12, 2026Read summary
Case ReportMedical GeneticsOpen access

A case of renal hypouricemia type 1 associated with compound heterozygous URAT1/SLC22A12 variants A209V and F379L: clinical evidence for their pathogenic significance.

A 69-year-old woman was evaluated for renal dysfunction and hypouricemia. Testing showed serum uric acid of 0.7 mg/dL and a fractional urate clearance (Cua/Ccr) of 60.5%, alongside CKD stage G3b and a renal stone.

CEN Case RepOct 12, 2026Read case
Clinical ResearchOncology (Medical)

Continuous intrathecal therapy for refractory cancer pain: A systematic review and meta-analysis focusing on partially implanted devices.

This systematic review and meta-analysis assessed partially implanted intrathecal devices (PIDs) for adults with refractory cancer-related pain, comparing them with conventional medical management and, in comparative…

Acta OncolOct 12, 2026Read summary
Clinical ResearchUrologyOpen access

Laparoscopic and robotic management of symptomatic calyceal diverticula: a systematic review on behalf of YAU and EAU endourology.

This systematic review assessed laparoscopic and robot-assisted management of symptomatic calyceal diverticula. Nine studies were included in a qualitative synthesis.

World J UrolOct 12, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Resilience interventions for stress-related health outcomes in patients with cancer: Findings from a systematic review of randomized controlled trials.

This systematic review synthesized randomized controlled trials of resilience interventions for stress-related health outcomes in patients with cancer.

Support Care CancerOct 12, 2026Read summary

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