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2000 articles

September 202624

Clinical ResearchUrologyOpen access

Changes in renal function in patients with chronic kidney disease after ureteroscopy: a systematic review and meta-analysis from EAU endourology.

This systematic review and meta-analysis evaluated changes in estimated glomerular filtration rate (eGFR) after ureteroscopy (URS) or retrograde intrarenal surgery (RIRS) in patients with chronic kidney disease (CKD).

UrolithiasisSep 28, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Sacituzumab tirumotecan in previously treated metastatic triple-negative breast cancer: a detailed safety analysis of the randomized OptiTROP-Breast01 study.

This randomized controlled trial analyzed the safety profile of sacituzumab tirumotecan (sac-TMT) in 262 patients with previously treated metastatic triple-negative breast cancer.

Breast Cancer ResSep 28, 2026Read summary
Case ReportPsychiatry

Helping or controlling? A multi-method case study of a mother-daughter dyad and their interactions during trauma-focused therapy.

This case study involved a 14-year-old girl undergoing intensive trauma-focused therapy, assessed alongside her mother over five weeks.

Eur J PsychotraumatolSep 28, 2026Read case
Clinical ResearchOncology (Medical)

Systemic and intracranial activity of antibody-drug conjugates in patients with non-small cell lung cancer and brain metastases: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed systemic and intracranial responses to antibody-drug conjugates (ADCs) in patients with non-small cell lung cancer and brain metastases.

Lung CancerSep 28, 2026Read summary
Case ReportInfectious DiseasesOpen access

Diagnostic Challenges in mNGS for Pulmonary Mucormycosis Presenting with Imaging Features Resembling Those of Lung Cancer.

A 67-year-old woman with diabetes presented with cough and sputum production. Imaging suggested lung cancer due to a right hilar mass, bronchial obstruction, and mediastinal lymphadenopathy.

Int Med Case Rep JSep 28, 2026Read case
Clinical ResearchNeurologyOpen access

Endovascular Treatment for Patients Aged ≥80 Years with Large Ischemic Stroke.

This randomized controlled trial evaluated the effectiveness and safety of endovascular treatment (EVT) in patients aged ≥80 years with large ischemic stroke.

Clin Interv AgingSep 28, 2026Read summary
Clinical ResearchCardiology

Stenting Technique and Clinical Outcome in True Bifurcation PCI: Insights From the OCTOBER Trial.

The OCTOBER trial analyzed 1,201 patients undergoing percutaneous coronary intervention for true bifurcation lesions to compare outcomes of 1-stent versus 2-stent techniques.

JACC Cardiovasc IntervSep 28, 2026Read summary
Case ReportAnesthesiologyOpen access

Effects of Ciprofol- versus Remimazolam-Based Total Intravenous Anesthesia on Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy: A Randomized Controlled Trial.

Postoperative nausea and vomiting (PONV) remains common after laparoscopic cholecystectomy. Whether ciprofol-based anesthesia reduces PONV compared with remimazolam-based anesthesia remains unclear.

Drug Des Devel TherSep 28, 2026Read case
Clinical ResearchOrthopedic Surgery

Multicentre randomised controlled trial protocol in China comparing postless hip arthroscopy with conventional perineal post-assisted hip arthroscopy to reduce perineal complications in patients undergoing hip arthroscopy for femoroacetabular impingement: the POSTLESS-HIP trial.

The POSTLESS-HIP trial is a multicentre, prospective, parallel-group, randomised controlled trial in China evaluating postless hip arthroscopy versus conventional perineal post-assisted hip arthroscopy in 270 patients…

BMJ OpenSep 28, 2026Read summary
Clinical ResearchEmergency Medicine

Efficacy of a needle-free blood collection device (PIVO Pro) for avoiding contaminated blood culture sets in Australian emergency departments: protocol for an adaptive group sequential randomised controlled trial.

This study protocol outlines a multicentre, adaptive group sequential randomised controlled trial aimed at evaluating the efficacy of the needle-free blood collection device, PIVO Pro, in reducing blood culture…

BMJ OpenSep 28, 2026Read summary
Case ReportOncology (Medical)

Abemaciclib and lenalidomide presenting with central retinal artery occlusion in a patient with breast cancer and multiple myeloma: a possible treatment-related association.

A woman in her late seventies with metastatic hormone receptor-positive breast cancer and multiple myeloma experienced sudden, painless vision loss in her right eye while on long-term abemaciclib and lenalidomide.

BMJ Case RepSep 28, 2026Read case
Clinical ResearchOncology (Medical)Open access

Second-Line Systemic Therapy Following First-Line FOLFIRINOX or NALIRIFOX in Metastatic Pancreatic Ductal Adenocarcinoma: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated second-line therapies following first-line FOLFIRINOX or NALIRIFOX in 3888 adults with metastatic pancreatic ductal adenocarcinoma.

J Gastrointest CancerSep 28, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Effects of concurrent training sequence on cardiometabolic risk factors in patients with type 2 diabetes: a systematic review and network meta-analysis.

This systematic review and network meta-analysis evaluated the effects of concurrent training sequences on cardiometabolic risk factors in patients with type 2 diabetes mellitus (T2DM).

EndocrineSep 28, 2026Read summary
Case ReportDermatology

Cutaneous T-cell lymphoma emerging during long-term dupilumab therapy in a patient with longstanding atopic diathesis: diagnostic challenges and mechanistic considerations.

A woman in her 40s with a long history of atopic dermatitis developed patch-stage mycosis fungoides after over 5 years of stable dupilumab therapy.

BMJ Case RepSep 28, 2026Read case
Clinical ResearchOncology (Medical)Open access

Circulating tumour DNA and its clinical relevance in predicting progression-free survival and overall survival in patients with advanced breast cancer: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the prognostic value of circulating tumour DNA (ctDNA) in predicting progression-free survival (PFS) and overall survival (OS) in patients with advanced breast cancer…

Breast Cancer Res TreatSep 28, 2026Read summary
Case ReportCardiologyOpen access

Extracorporeal cardiopulmonary resuscitation for cardiogenic shock in a Jehovah's witness.

A Jehovah's Witness patient in cardiogenic shock underwent successful resuscitation using veno-arterial extracorporeal membrane oxygenation (ECMO) without the need for blood transfusions.

J Artif OrgansSep 28, 2026Read case
Case ReportOphthalmology

Buckle infection and exudative retinal detachment following a deep scleral bite: management and outcome.

During a standard 279 scleral buckle (SB) procedure, an inadvertent deep scleral suture bite occurred. On postoperative day (POD) 5, the patient presented with pain, reduced vision (counting fingers close to the face)…

BMJ Case RepSep 28, 2026Read case
Clinical ResearchNephrology

Effectiveness and Safety of Virtual Reality Interventions for Symptom Management in Adults Undergoing Hemodialysis: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis evaluated the effectiveness and safety of virtual reality (VR) interventions for symptom management in adults undergoing hemodialysis.

J Med Internet ResSep 28, 2026Read summary
Clinical ResearchNeurologyOpen access

Intravenous thrombolysis use before interhospital transfer for thrombectomy: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of intravenous thrombolysis (IVT) before interhospital transfer for endovascular thrombectomy (EVT) in patients with large-vessel occlusion acute ischemic…

J NeurolSep 28, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Population Pharmacokinetics and Exposure-response Analysis of Durvalumab in Patients with Limited-stage Small-cell Lung Cancer in the Phase 3 ADRIATIC Study.

The ADRIATIC study evaluated the population pharmacokinetics and exposure-response relationships of durvalumab in patients with limited-stage small-cell lung cancer (LS-SCLC).

AAPS JSep 28, 2026Read summary
Clinical ResearchCardiology

Responder analysis of adaptive postural balance cardiac rehabilitation exercise in patients with coronary artery disease and type 2 diabetes: secondary analysis of a randomized trial.

This secondary analysis of a randomized trial evaluated the effects of adaptive postural balance cardiac rehabilitation exercise (APBCRE) versus aerobic exercise (AE) in 167 patients with coronary artery disease and…

Scand Cardiovasc JSep 28, 2026Read summary
Case ReportOncology (Medical)

Primary adrenal lymphoma presenting as primary adrenal insufficiency.

A man in his late 60s presented with symptoms of adrenal failure, including anaemia and hypercalcaemia. Initial tests indicated adrenal insufficiency, and imaging showed bilateral adrenal enlargement.

BMJ Case RepSep 28, 2026Read case
Clinical ResearchEndocrinologyOpen access

Non-thyroidal illness syndrome and isolated low triiodothyronine as prognostic markers in acute illness: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the relationship between thyroid hormone alterations and mortality in critically ill and cardiovascular patients.

EndocrineSep 28, 2026Read summary
Case ReportGeneral Surgery

Jejunal transection caused by postoperative adhesive small bowel obstruction: managed simultaneously with abdominal aortic aneurysm.

A man in his 90s presented with abdominal pain, diagnosed with postoperative adhesive small bowel obstruction and an abdominal aortic aneurysm (AAA).

BMJ Case RepSep 28, 2026Read case

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