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2000 articles

September 202624

Clinical ResearchGeriatricsOpen access

Does baseline physical function modify the response to a physical activity intervention in adults with arthritis? A secondary analysis of a randomized trial.

This secondary analysis of a randomized controlled trial examined whether baseline physical function influenced the response to a telephone-delivered Walk With Ease (WWE-T) intervention in 267 adults with arthritis.

Rheumatol IntSep 30, 2026Read summary
Clinical ResearchGastroenterologyOpen access

16S rRNA Datasets of Gut Microbiota in Stent-Based Diverting Technique and Ileostomy from A Prospective, Open-Label, Multicenter Randomized Controlled Trial.

This study presents a 16S rRNA amplicon dataset from a multicenter randomized controlled trial involving 80 patients undergoing either a stent-based diverting technique (SDT) or ileostomy after rectal cancer surgery.

Sci DataSep 30, 2026Read summary
Clinical ResearchInfectious Diseases

Effectiveness and safety of the available preventive tuberculosis treatment regimens for children and adolescents: systematic review and network meta-analysis.

This systematic review and network meta-analysis evaluated the effectiveness and safety of tuberculosis (TB) treatment regimens in children and adolescents under 18 years.

BMJ Paediatr OpenSep 30, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Safety and efficacy of human gingiva-derived mesenchymal stem cells in patients with type 1 diabetes: a double-blind, randomized, placebo-controlled, phase 1 trial.

This phase 1 double-blind, randomized, placebo-controlled trial evaluated the safety and efficacy of human gingiva-derived mesenchymal stem cells (GMSCs) in 18 patients with type 1 diabetes mellitus (T1DM).

Signal Transduct Target TherSep 30, 2026Read summary
Case ReportGastroenterology

When seizure control comes at a cost: valproic acid-induced necrotising pancreatitis in a patient receiving antiepileptic polypharmacy.

A man in his late 20s with psychiatric and metabolic comorbidities developed acute necrotising pancreatitis while on antiepileptic polypharmacy, including valproic acid.

BMJ Case RepSep 30, 2026Read case
Clinical ResearchOrthopedic SurgeryOpen access

Operative treatment of high-grade medial collateral ligament injury and chronic medial knee instability: a systematic review.

This systematic review assessed the operative treatment of high-grade medial collateral ligament (MCL) injuries and chronic medial knee instability, focusing on clinical phenotype rather than MCL grade.

Arch Orthop Trauma SurgSep 30, 2026Read summary
Clinical ResearchPediatrics

Does a Simple Touch Make a Difference? The Effect of Acupressure on Pain Scores in Infants Undergoing Cardiac Catheterization: A Randomized, Placebo-Controlled Trial.

This randomized, placebo-controlled trial evaluated acupressure in 60 infants aged 1–12 months with congenital heart disease undergoing cardiac catheterization.

J Cardiovasc NursSep 30, 2026Read summary
Case ReportHematology

POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder and skin changes) associated with Castleman disease and latent tuberculosis: a diagnostic challenge.

A woman in her 40s presented with progressive multisystem disease, including chronic distal neuropathy, constitutional decline, lymphadenopathy, and serosal effusions.

BMJ Case RepSep 30, 2026Read case
Case ReportGastroenterology

Intentional nail ingestion with caecal impaction: colonoscopic removal using a cap-assisted technique.

A woman with a history of recurrent nail ingestion presented with abdominal pain after swallowing multiple nails. Initial conservative management showed progressive migration of the nails, which clustered near the…

BMJ Case RepSep 30, 2026Read case
Clinical ResearchCardiology

Age and antiplatelet de-escalation after myocardial infarction in the TALOS-AMI trial.

This secondary analysis of the TALOS-AMI randomized trial evaluated the effects of de-escalating from ticagrelor to clopidogrel on clinical outcomes in patients after myocardial infarction, stratified by age.

Ann MedSep 30, 2026Read summary
Clinical ResearchNephrology

Rituximab as Rescue or Add-On Therapy for Relapsing or Refractory Lupus Nephritis: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the efficacy of rituximab (RTX) as rescue or add-on therapy for relapsing or refractory lupus nephritis in 445 patients.

Clin Transl SciSep 30, 2026Read summary
Case ReportOncology (Medical)

Metastasis of Invasive Ductal Carcinoma of the Breast to the Uterine Cervix 30 Years Post-Mastectomy: A Case Report.

A 69-year-old woman, 30 years post-mastectomy for invasive ductal carcinoma, presented with abnormal cervical cytology. Imaging revealed a 38-mm cervical mass, leading to a modified radical hysterectomy.

J Obstet Gynaecol ResSep 30, 2026Read case
Clinical ResearchPhysical Medicine & Rehabilitation

Effectiveness, Mediators and Moderators of Remote Live vs. Pre-Recorded Physical Exercise Training for Chronic Low Back Pain.

This randomized controlled trial evaluated the effectiveness of live interactive versus pre-recorded remote exercise training for chronic low back pain (CLBP) in 94 patients.

Eur J PainSep 30, 2026Read summary
Clinical ResearchEmergency Medicine

Reducing Peripheral Intravenous Catheter Use in Adult Acute Care: A Systematic Review.

This systematic review evaluated interventions aimed at reducing peripheral intravenous catheter (PIVC) use in adult acute care settings.

Emerg Med AustralasSep 30, 2026Read summary
Clinical ResearchGastroenterology

Endoscopic Ultrasound-Guided Hepaticogastrostomy With Plastic Stent Versus Metallic Stent for Malignant Biliary Obstruction: A Meta-Analysis.

This meta-analysis evaluated the efficacy and safety of plastic versus metal stents in endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS) for malignant biliary obstruction.

Dig EndoscSep 30, 2026Read summary
Clinical ResearchNeurology

Repetitive Transcranial Magnetic Stimulation Combined With Median Nerve Electrical Stimulation for Severe Traumatic Brain Injury.

This randomized controlled trial investigated the effects of repetitive transcranial magnetic stimulation (rTMS) combined with median nerve electrical stimulation (MNS) in 86 patients with severe traumatic brain injury…

Brain BehavSep 30, 2026Read summary
Clinical ResearchEndocrinology

Urinary dipstick findings and UTI risk with SGLT2 inhibitors: a post-hoc analysis of the CANVAS and CREDENCE trials.

This post-hoc analysis of the CANVAS and CREDENCE trials evaluated the relationship between urinary dipstick findings and UTI risk in 8614 participants with type 2 diabetes.

Nephrol Dial TransplantSep 30, 2026Read summary
Clinical ResearchOrthopedic Surgery

Clinical outcomes of hyaluronic acid-sorbitol injection in athletes with patellofemoral pain: Evaluation of the potential influence of body mass index.

This prospective clinical trial evaluated the effects of a single 4 mL hyaluronic acid-sorbitol injection on knee function in 60 athletes aged 30-55 with patellofemoral pain (PFP) over 6 months.

PLoS OneSep 30, 2026Read summary
Case ReportGeneral Surgery

Treatment of Seven Severely Atrophic Maxillary Full-Arch Cases Using Digitally Planned and Produced Immediately Loaded Screw-Retained Subperiosteal Implants: A Case Series with Surgical and Initial Prosthetic Outcomes.

This case series details the treatment of seven patients with severely atrophic maxillae using digitally planned and custom-milled subperiosteal implants.

Int J Oral Maxillofac ImplantsSep 30, 2026Read case
Case ReportPediatricsOpen access

Isolated clival Langerhans cell histiocytosis in a pediatric patient: systematic review and illustrative case report.

A 3.5-year-old boy presented with isolated clival Langerhans cell histiocytosis, confirmed through histopathological and immunohistochemical evaluation.

Childs Nerv SystSep 30, 2026Read case
Case ReportCardiothoracic Surgery

Cardiac intimal sarcoma presenting with pseudo-pulmonary embolism: surgical debulking, RVOT reconstruction and pulmonary valve replacement.

A 27-year-old woman presented with dyspnoea and signs of right-heart failure following delivery. Initial imaging suggested pulmonary embolism, prompting emergency surgery due to haemodynamic instability.

Multimed Man Cardiothorac SurgSep 30, 2026Read case
Case ReportCardiothoracic Surgery

Transverse infundibulotomy for resection of a right ventricular outflow tract myxoma.

A 25-year-old asymptomatic 64 kg female with an incidental heart murmur was found, on echocardiography, to have a 2 cm echogenic mass beneath the pulmonary valve, with a peak gradient of 11 mmHg and mild pulmonic…

Multimed Man Cardiothorac SurgSep 30, 2026Read case
Clinical ResearchEndocrinologyOpen access

Supporting Caregivers Behind Youth with T1D: A Systematic Review of Psychosocial Interventions and Youth Glycemic Outcomes.

This systematic review analyzed 26 studies on psychosocial interventions for parents of children with Type 1 Diabetes (T1D) from 2019 to 2025.

Curr Diab RepSep 30, 2026Read summary
Clinical ResearchCardiology

Oral anticoagulant monotherapy versus oral anticoagulant plus antiplatelet therapy in adults with stable coronary artery disease.

This is a protocol for a Cochrane review (intervention). The objectives are as follows: To assess the benefits and harms of oral anticoagulant monotherapy compared with oral anticoagulant plus antiplatelet therapy in…

Cochrane Database Syst RevSep 30, 2026Read summary

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