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2000 articles
September 202624
Vulvar Crohn's-Case Series and Review of Treatment With Ustekinumab.
This case series presents three patients with cutaneous vulvar Crohn's disease (VCD), a rare and challenging condition. Each patient was treated with different biologic agents.
Radiotherapy versus observation following surgical resection of WHO grade 2 atypical meningioma (ROAM/EORTC-1308): an international, multicentre, open-label, phase 3, randomised controlled trial.
ROAM/EORTC-1308 was an international, multicentre, open-label, phase 3 randomised trial comparing adjuvant radiotherapy with observation after complete resection of newly diagnosed WHO grade 2 atypical meningioma.
ATM mutations in myelodysplastic neoplasms, acute myeloid leukemia, and myeloproliferative neoplasms: a systematic review.
This systematic review evaluated the impact of ATM mutations in myelodysplastic neoplasms (MDS), acute myeloid leukemia (AML), and myeloproliferative neoplasms (MPN).
Predictors of Pulmonary Complications After Rib Fractures: Systematic Review and Meta-Analyses.
This systematic review and meta-analysis examined multivariable-adjusted predictors of pulmonary complications in adults with blunt rib fractures.
Effectiveness of cognitive behavioral therapy for postpartum depression: a systematic review and meta‑analysis.
This systematic review and meta-analysis assessed cognitive behavioral therapy (CBT) for postpartum depression (PPD), comparing it with usual care in randomized controlled trials.
Lymphocutaneous sporotrichosis: A case report from southeastern China and review of the literature.
A 53-year-old male presented with multiple ulcerated lesions, leading to a diagnosis of lymphocutaneous sporotrichosis. Pathological analysis showed an inflammatory reaction, while imaging studies were normal.
Wearable Sensors in Gait Assessment for Parkinson Disease and Stroke in Real-World Environments: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the use of wearable sensors for gait assessment in patients with Parkinson disease (PD) and stroke. It included 43 studies, primarily focusing on PD (2774 participants).
Iberdomide plus daratumumab and dexamethasone versus daratumumab, bortezomib, and dexamethasone in patients with relapsed or refractory multiple myeloma (EXCALIBER-RRMM): an open-label, randomised, controlled, phase 3 trial.
EXCALIBER-RRMM is an ongoing, open-label, randomised phase 3 trial comparing iberdomide, daratumumab, and dexamethasone with daratumumab, bortezomib, and dexamethasone in adults with relapsed or refractory multiple…
Lower Limb Necrotizing Soft Tissue Infection Associated with Corynebacterium minutissimum in an Adolescent: A Case Report and Surgical Management.
A 14-year-old boy presented with progressive ulceration, swelling, and malodor in the left lower leg, leading to a diagnosis of necrotizing soft tissue infection (NSTI).
Blood pressure targets for hypertension in people with diabetes mellitus.
This Cochrane systematic review protocol aims to evaluate whether lower blood pressure targets (≤ 130/85 mmHg) reduce mortality and morbidity compared to standard targets (≤ 140 to 160/90 to 100 mmHg) in individuals…
Unravelling deregulated metabolites in seminal plasma of infertile men: a systematic review and bioinformatic analysis.
This systematic review analyzed metabolomic studies comparing seminal plasma metabolites in healthy and infertile men. It included 20 studies and identified 284 metabolites, with specific alterations linked to…
Comparative pain relief and functional outcomes following robotic-assisted versus conventional total knee arthroplasty: a GRADE-assessed meta-analysis with meta-regression of randomized controlled trials.
This meta-analysis of 24 randomized controlled trials involving 3,425 patients compared robotic-assisted total knee arthroplasty (RA-TKA) with conventional TKA (C-TKA).
Sequential combination of anti-PD-1 antibody and PEG-IFNα in chronic hepatitis B patients: correlates of HBsAg loss with enhanced T-cell responses.
This pilot clinical trial investigated the sequential combination of anti-PD-1 antibody (sintilimab) and PEG-IFNα in ten virologically suppressed chronic hepatitis B patients.
A previously unreported ELOVL4 frameshift variant in a patient with early severe cognitive decline, parkinsonism, and cerebellar ataxia: A case report.
A 35-year-old man presented with a 5-year history of progressive cognitive decline, parkinsonism, and cerebellar ataxia. Neurological examination revealed significant motor and cognitive impairments, with imaging…
Temporally Based Orbicularis Oculi Myocutaneous Flap for Pediatric Postexcisional Cicatricial Lower Eyelid Ectropion: A Case Report.
A pediatric patient developed cicatricial lower eyelid ectropion after two local excisions of a congenital melanocytic nevus at another institution.
Western versus Asian utilization of molecular testing for indeterminate thyroid nodules: A meta-analysis of divergent clinical impact.
This meta-analysis examined the use of molecular testing (MT) for indeterminate thyroid nodules in Western and Asian populations.
Network meta-analysis of intrathyroidal injection of combined dexamethasone with lidocaine for subacute thyroiditis.
This meta-analysis evaluated the efficacy of intrathyroidal dexamethasone (Dex) versus oral prednisone and compared combination therapy of Dex with lidocaine to monotherapy in treating subacute thyroiditis (SAT).
Giant subpatellar synovial osteochondromatosis complicated by osteoarthritis of the knee: A case report.
A 71-year-old woman presented with a 2-year history of progressive pain and swelling in her left knee, leading to significant movement restriction and impairment in daily activities.
Power Doppler ultrasonography for positional graft compression after femoral artery reconstruction: A case report.
A 35-year-old male presented with pain and numbness during deep knee flexion, 3.5 years post-femoral artery reconstruction using the great saphenous vein.
Comparative efficacy of various non-pharmacological therapies on cognitive function in patients with mild cognitive impairment or dementia: A network meta-analysis.
This network meta-analysis evaluated the efficacy of non-pharmacological therapies on cognitive function in 2082 patients with mild cognitive impairment or dementia.
Critical Kennedy's disease with Guillain-Barré syndrome and respiratory failure: A case report.
A 61-year-old man with a 35-year history of Kennedy disease presented with acute respiratory failure, dysphagia, and progressive dyspnea.
Progression-free survival and objective response rate as a surrogate end point for overall survival in metastatic renal cell carcinoma: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the validity of progression-free survival (PFS) and objective response rate (ORR) as surrogate endpoints for overall survival (OS) in randomized controlled trials of…
The Psychosocial Impact of Receiving Whole Genome and Whole Exome Sequencing Results in Adults: A Systematic Review.
This systematic review assessed the psychosocial impact of whole genome sequencing (WGS) and whole exome sequencing (WES) results in adults, analyzing 45 studies.
Vision loss as the first manifestation of isolated cns relapse in CML blast crisis during flumatinib maintenance therapy: A case report.
A 65-year-old male with chronic myeloid leukemia in complete remission presented with progressive vision loss, indicating isolated CNS relapse.
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