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785 articles

September 202624

Clinical ResearchGastroenterology

Thymosin-ɑ1 for people with chronic hepatitis B.

This systematic review and meta-analysis evaluated the efficacy of thymosin-α1 in treating chronic hepatitis B across 10 randomized controlled trials involving 1349 participants.

Cochrane Database Syst RevSep 9, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Comparative Efficacy and Safety of Transarterial Therapies for Unresectable Neuroendocrine Liver Metastases: A Systematic Review.

This systematic review compared transarterial embolisation, conventional and drug-eluting-bead chemoembolisation, and radioembolisation for adults with unresectable neuroendocrine liver metastases.

Cardiovasc Intervent RadiolSep 9, 2026Read summary
Clinical ResearchCardiology

Patient-reported barriers to dietary adherence in heart failure: a qualitative substudy of the Pro-HEART trial.

This qualitative substudy of the Pro-HEART randomized controlled trial examined barriers to dietary adherence in 24 participants with heart failure during a 12-week weight-loss phase.

Eur J Cardiovasc NursSep 8, 2026Read summary
Clinical ResearchGeneral Surgery

Impact of PerioperAtive LidocAine Infusions on Enhanced Recovery After Noncardiac Surgery (IMPALA-ERAS) in an inpatient setting: rationale, design and protocol for a sequential, repeated crossover trial.

The IMPALA-ERAS trial is a single-centre, pragmatic, cluster-randomised, double-blinded, placebo-controlled study evaluating the effects of perioperative intravenous lidocaine infusions on postoperative recovery in 2290…

BMJ OpenSep 8, 2026Read summary
Clinical ResearchOncology (Medical)

Multidisciplinary mHealth Rehabilitation for Patients With Abdominal Cancer Who Are Receiving Chemoradiotherapy: Randomized Phase II Trial.

This randomized phase II trial evaluated a multidisciplinary mHealth rehabilitation program for 111 patients with abdominal cancer undergoing concurrent chemoradiotherapy (CCRT).

J Med Internet ResSep 8, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Tranexamic Acid Administration in Laparoscopic Sleeve Gastrectomy.

This systematic review and meta-analysis assessed tranexamic acid (TXA) during laparoscopic sleeve gastrectomy (LSG), drawing on 9 studies with 1665 patients: 842 received TXA and 823 received no intervention or…

Obes SurgSep 8, 2026Read summary
Clinical ResearchGastroenterology

HBsAg decline and clearance with peg-IFN therapy added to nucleos(t)ide analogues: an individual participant data meta-analysis of prospective trials (PROSPER).

This meta-analysis evaluated the impact of peg-interferon (peg-IFN) therapy added to nucleos(t)ide analogue (NA) treatment in chronic hepatitis B patients.

GutSep 7, 2026Read summary
Clinical ResearchGastroenterology

A clinical study on the efficacy of rectal administration of Tongfu Qinghua decoction combined with external application of Ruyi Jinhuang powder in treating acute pancreatitis .

This randomized controlled trial evaluated the efficacy of rectal Tongfu Qinghua decoction combined with Ruyi Jinhuang powder in 100 patients with acute pancreatitis.

Pak J Pharm SciSep 6, 2026Read summary
Clinical ResearchGastroenterology

Efficacy of Proton Pump Inhibitor Therapy for Nocturnal GERD Symptoms and Associated Sleep Disturbances: A Systematic Review of Randomized Controlled Trials.

This systematic review evaluated the efficacy of proton pump inhibitor (PPI) therapy for nocturnal gastroesophageal reflux disease (GERD) symptoms and associated sleep disturbances in adults.

J Clin GastroenterolSep 6, 2026Read summary
Clinical ResearchGastroenterology

Meta-analysis of the Effects of Probiotics on Alcoholic Liver Disease.

This meta-analysis evaluated the impact of probiotics on liver function markers in patients with alcoholic liver disease (ALD), analyzing 15 randomized controlled trials.

Nutr RevSep 6, 2026Read summary
Clinical ResearchGastroenterology

The Role of Artificial Intelligence Combined With Digital Cholangioscopy for Indeterminant and Malignant Biliary Strictures: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis evaluated the diagnostic performance of artificial intelligence (AI) combined with digital cholangioscopy for indeterminant and malignant biliary strictures.

J Clin GastroenterolSep 6, 2026Read summary
Case ReportGastroenterology

One-Stage Percutaneous Self-Expandable Metal Stent Placement for Malignant Biliary Obstruction: A Five-Case Series.

This report details five patients with malignant biliary obstruction who underwent one-stage percutaneous self-expandable metal stent (SEMS) placement due to failed ERCP.

Tokai J Exp Clin MedSep 6, 2026Read case
Case ReportMedical Genetics

C12ORF54 mediates lipid droplet delivery to lysosomes with mutation causing childhood-onset metabolic dysfunction-associated steatotic liver disease.

A 2-year-old boy presented with metabolic dysfunction-associated steatotic liver disease (MASLD) and was found to have a homozygous missense variant in the C12ORF54 gene.

Biochim Biophys Acta Mol Basis DisSep 6, 2026Read case
Clinical ResearchGastroenterologyOpen access

DSM-TACE Versus Conventional Approaches in HCC: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis compared degradable starch microsphere transarterial chemoembolization (DSM-TACE) with conventional TACE or drug-eluting bead TACE in patients with hepatocellular carcinoma.

Cardiovasc Intervent RadiolSep 6, 2026Read summary
Case ReportAnesthesiology

Perioperative management of a child with X-linked erythropoietic protoporphyria undergoing dental surgery in preparation for liver transplantation.

A middle-childhood-aged female with X-linked erythropoietic protoporphyria (XLEPP) and end-stage liver disease required urgent dental extractions for liver transplantation preparation.

BMJ Case RepSep 5, 2026Read case
Clinical ResearchOncology (Medical)Open access

The effect of a smartphone-based educational intervention on the supportive care needs of family caregivers of patients with colorectal cancer: a randomized controlled trial.

This randomized controlled trial evaluated the impact of a smartphone-based educational program on the supportive care needs of family caregivers of colorectal cancer patients.

Support Care CancerSep 5, 2026Read summary
Case ReportGastroenterology

CytoSorb Application for Successful Control of Life-Threatening Gastrointestinal Bleeding Following Rivaroxaban Administration.

A 68-year-old man with a history of colonic diverticular disease experienced severe lower gastrointestinal bleeding while on rivaroxaban.

Am J Case RepSep 4, 2026Read case
Clinical ResearchGastroenterology

Blood Bile Acids for Inflammatory Bowel Disease Diagnosis and Disease Activity Assessment: A Metabolomics Meta-Analysis.

This meta-analysis examined blood bile acid (BA) profiles in inflammatory bowel disease (IBD) by analyzing 28 studies involving 5056 IBD patients and 1721 healthy controls.

J Proteome ResSep 4, 2026Read summary
Clinical ResearchGastroenterology

Gut microbiota and metabolic alterations in participants with flatulence identify Faecalibacterium prausnitzii as a key microbial target for clinical intervention.

This randomized controlled trial investigated the gut microbiota and metabolic changes in participants with flatulence, identifying Faecalibacterium prausnitzii as a crucial microbial target.

Gut MicrobesSep 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Goal-directed nutritional support in preserving muscle mass and optimising recovery in treatment of oesophageal cancer: results of a prospective non-randomised cluster trial.

This prospective non-randomised cluster trial evaluated the impact of a goal-directed nutritional support protocol (GDNS) on muscle mass and survival in adults with oesophageal cancer undergoing neoadjuvant…

Support Care CancerSep 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Prevalence of Claudin 18.2 Expression in Gastric and Gastroesophageal Junction Adenocarcinoma: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the prevalence of CLDN18.2 expression in gastric and gastroesophageal junction adenocarcinoma across 22 studies involving 12,173 patients.

J Gastrointest CancerSep 3, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Sodium-glucose cotransporter-2 inhibitors and gastrointestinal neoplasm risk in type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the association between sodium-glucose cotransporter 2 (SGLT2) inhibitors and gastrointestinal neoplasm risk in patients with type 2 diabetes mellitus (T2DM).

Clin Exp MedSep 3, 2026Read summary
Clinical ResearchGastroenterology

Prognostic value of liver histology in steatotic liver disease: a systematic literature review and meta-analysis.

This systematic review and meta-analysis evaluated the relationship between histologic liver fibrosis and clinical outcomes in patients with metabolic dysfunction-associated steatohepatitis (MASH) and steatotic liver…

J Comp Eff ResSep 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Exploring disparities in adherence to colorectal cancer clinical practice guidelines and associated survival outcomes: a systematic review and meta-analysis.

This systematic review and meta-analysis examined adherence to colorectal cancer clinical practice guidelines (CPGs) and its impact on survival outcomes.

Support Care CancerSep 2, 2026Read summary

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