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1002 articles

September 202621

Clinical ResearchCardiologyOpen access

Left Ventricular Global Longitudinal Strain as a Marker of Subclinical Myocardial Dysfunction in Youths With Type 1 Diabetes Mellitus: An Updated Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated Left Ventricular Global Longitudinal Strain (LV GLS) in youths with type 1 diabetes mellitus (T1DM) compared to healthy controls.

Diabetes Metab Res RevSep 1, 2026Read summary
Clinical ResearchPediatricsOpen access

Association Between Diaphragm Ultrasound Measures and Extubation Outcomes in Neonates: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the relationship between diaphragm ultrasound measures and extubation outcomes in mechanically ventilated neonates.

Pediatr PulmonolSep 1, 2026Read summary
Case ReportCardiologyOpen access

Gamified Cardiopulmonary Rehabilitation in a Child Undergoing LVAD Bridging Therapy to Heart Transplantation: A Case Report.

A 6-year-old girl undergoing left ventricular assist device (LVAD) therapy for heart transplantation received a comprehensive, gamified cardiopulmonary rehabilitation program.

Nurs Crit CareSep 1, 2026Read case
Clinical ResearchPediatricsOpen access

Intervention Effect of Child Life Specialists on Paediatric Patients: A Systematic Review of Randomized Controlled Trials.

This systematic review and meta-analysis evaluated the impact of child life specialists (CLSs) on pediatric patients, analyzing 12 randomized controlled trials with 1096 participants.

Child Care Health DevSep 1, 2026Read summary
Case ReportInfectious DiseasesOpen access

Use of Expanded Access Fosmanogepix in Two Pediatric Patients With Rhino-Orbital-Cerebral Mucormycosis.

Two pediatric patients with diabetic ketoacidosis presented with extensive rhino-orbital-cerebral mucormycosis. Initial treatment with standard antifungal therapies failed to eradicate the infection.

PharmacotherapySep 1, 2026Read case
Case ReportPediatrics

Congenital Tuberculosis in a 2-Week-Old Neonate With an Asymptomatic Mother.

A 2-week-old male neonate presented with poor feeding and low-grade fever. Initial cultures and viral PCRs were negative, but worsening symptoms led to hospitalization.

PediatricsSep 1, 2026Read case
Case ReportPediatrics

Two-Year-Old Girl With Chronic Cough and Lymphadenopathy.

A 27-month-old girl with no significant medical history presented with a chronic cough lasting three months, accompanied by one day of fever and rhinorrhea.

PediatricsSep 1, 2026Read case
Clinical ResearchPediatrics

Early Exclusive Enteral Feeding in Preterm Infants: A Meta-Analysis.

This meta-analysis evaluated early exclusive enteral feeding (EEF) versus progressive enteral feeding (PEF) in preterm infants across 11 randomized controlled trials involving 3145 participants.

PediatricsSep 1, 2026Read summary
Clinical ResearchMedical Genetics

Safety and efficacy of guanabenz in early-childhood onset vanishing white matter: primary analysis of a single-arm, phase 1/2 trial.

This single-arm, phase 1/2 trial evaluated the safety and efficacy of guanabenz in 31 children with early-childhood onset vanishing white matter.

Lancet NeurolSep 1, 2026Read summary
Case ReportMedical Genetics

Extra-Endocrine Features in Infancy as Early Clues to MEN2B.

This case series discusses five pediatric patients diagnosed with multiple endocrine neoplasia type 2B (MEN2B), all carrying the RET proto-oncogene mutation (M918T).

PediatricsSep 1, 2026Read case
Clinical ResearchAllergy & Immunology

Asthma Exacerbation Risk and School Asthma Readiness.

This randomized controlled trial evaluated school asthma readiness and its association with asthma exacerbations in a cohort of 202 children aged 5 to 13 years, predominantly Black and non-Hispanic.

PediatricsSep 1, 2026Read summary
Clinical ResearchPediatrics

Virtual Health Interventions to Improve Breastfeeding: A Systematic Review.

This systematic review evaluated the effectiveness of various virtual breastfeeding interventions on breastfeeding duration and exclusivity.

PediatricsSep 1, 2026Read summary
Case ReportPediatrics

Anakinra in Severe RSV-Associated Autoinflammatory Encephalopathy With Delayed ADEM-Like Changes.

Two previously healthy children developed rapidly progressive encephalopathy following RSV infection. Initial brain MRI scans were normal, but subsequent imaging revealed multifocal white matter lesions resembling acute…

PediatricsSep 1, 2026Read case
Clinical ResearchEndocrinologyOpen access

Comparing the Effectiveness of Different Types of Orthoses in Preventing Diabetic Foot Ulcer Recurrence: A Systematic Review of Randomized Clinical Trials.

This systematic review evaluated the effectiveness of various orthoses in preventing diabetic foot ulcer (DFU) recurrence among patients with diabetes.

J Foot Ankle ResSep 1, 2026Read summary
Clinical ResearchPsychiatryOpen access

Deprescription of Psychotropics in Children and Adolescents: Systematic Review of Guidelines and Development of a Deprescribing Algorithm.

This systematic review evaluated clinical practice guidelines for deprescribing psychotropics in children and adolescents. Among 1390 records, none met formal criteria for guidelines, but two papers provided…

Basic Clin Pharmacol ToxicolSep 1, 2026Read summary
Clinical ResearchPsychiatryOpen access

The Stigmatization of Caregivers of Children With Attention-Deficit/Hyperactivity Disorder: A Systematic Review.

This systematic review examined the stigmatization of caregivers of children with Attention-Deficit/Hyperactivity Disorder (ADHD) by analyzing 15 studies published between 2013 and 2024.

Fam ProcessSep 1, 2026Read summary
Clinical ResearchPediatrics

Interventions to Reduce Monitor Alarms Across Pediatric Inpatient Settings: A Systematic Review.

This systematic review evaluated interventions aimed at reducing alarm frequency from physiologic monitors in pediatric inpatient settings, including NICUs, PICUs, and MSUs.

Hosp PediatrSep 1, 2026Read summary
Case ReportPediatrics

"It Wasn't Nonadherence": Administrative Workload for Families and Inequitable Outcomes.

Mateo, a 7-year-old with medical complexity, was admitted for respiratory distress. His hospitalization was complicated by systemic issues, including language barriers and administrative demands that hindered his…

Hosp PediatrSep 1, 2026Read case
Clinical ResearchPediatrics

Efficacy and safety of short- versus standard-course ceftriaxone therapy in children with pneumonia: A randomized trial.

This randomized controlled trial evaluated the efficacy and safety of short-course (5-7 days) versus standard-course (7-14 days) ceftriaxone therapy in 200 children aged 1-14 years with pneumonia.

Pak J Pharm SciSep 1, 2026Read summary
Case ReportGastroenterologyOpen access

Novel SLC10A2 variants induce primary bile acid malabsorption and dysbiosis with IBD-like features.

We describe biochemically and functionally validated primary bile acid malabsorption caused by novel biallelic SLC10A2 variants in a child initially diagnosed with Crohn's disease.

Inflamm Bowel DisSep 1, 2026Read case
Case ReportDermatology

ALA-PDT for giant condyloma acuminatum in an immunodeficient child with BCL11B mutation: safety and efficacy.

A pair of siblings with a BCL11B mutation presented with giant condyloma acuminatum and intellectual developmental disorder.

Photodiagnosis Photodyn TherSep 1, 2026Read case

August 20263

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