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1821 articles
September 202624
Ultra-processed food consumption and risk of multiple chronic diseases among 8,819,894 adults from 51 prospective cohorts: a dose-response meta-analysis.
This meta-analysis examined the relationship between ultra-processed food (UPF) consumption and the risk of chronic diseases in 8,819,894 adults across 51 prospective cohorts.
Anti-OJ antibody-positive anti-synthetase syndrome associated with hepatocellular carcinoma.
A man in his 70s with hepatocellular carcinoma presented with progressive proximal muscle weakness and dropped head syndrome.
Durable remission of sinonasal mucosal melanoma despite early ICI discontinuation and risankizumab treatment for irAEs.
A patient with metastatic sinonasal mucosal melanoma experienced a remarkable and durable response to immune checkpoint inhibitors despite early treatment discontinuation due to severe immune-related adverse events.
Neoplastic mimicry of arterial disease.
Two patients presented with vascular symptoms and were admitted to a vascular surgery unit. Upon further investigation, the underlying cause of their symptoms was determined to be neoplastic rather than vascular in…
Severe, reversible alectinib-induced acute kidney injury requiring dialysis in an elderly patient with metastatic non-small cell lung cancer.
An elderly patient with advanced ALK-rearranged non-small cell lung cancer developed severe acute kidney injury requiring dialysis shortly after starting alectinib.
A workbook- and audio-administered, telephone-guided, low-intensity cognitive behavioural therapy intervention (EJDeR) for parents of persons treated for cancer during childhood: protocol for the CHANGE-pilot randomised controlled trial.
The CHANGE-pilot trial is a parallel-group, two-arm, pilot randomized controlled trial assessing the feasibility of the EJDeR intervention, a low-intensity cognitive behavioural therapy for parents of children treated…
Where do delays occur? A systematic review of the barriers to early breast cancer diagnosis across South Africa's health system.
This systematic review examined barriers to early breast cancer diagnosis in South Africa, where the 5-year survival rate is only 40%.
CT-derived myocardial extracellular volume: current evidence, clinical utility, and the emerging role of photon-counting CT-a systematic review.
This systematic review evaluated the clinical utility of CT-derived myocardial extracellular volume (ECV) across various cardiovascular diseases.
Transanal tube for the prevention of anastomotic leakage in rectal cancer surgery.
This systematic review and meta-analysis evaluated the effectiveness of a transanal tube in preventing anastomotic leakage in rectal cancer surgery, involving 1318 participants across four randomized controlled trials.
Stereotactic Body Radiotherapy vs Moderately Hypofractionated IMRT for Localized Intermediate-Risk Prostate Cancer: A Randomized Clinical Trial.
This phase-3 randomized clinical trial compared stereotactic body radiotherapy (SBRT) to moderately hypofractionated intensity-modulated radiation therapy (MH-IMRT) in patients with localized intermediate-risk prostate…
Recovery of ovarian function after chemotherapy in premenopausal women with breast cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated ovarian function recovery post-chemotherapy in 10,216 premenopausal women with breast cancer.
Asynchronous bilateral pulmonary pathology: left-sided congenital pulmonary airway malformation with contralateral malignant pleuropulmonary blastoma in an adolescent.
An adolescent boy with a history of left-sided congenital pulmonary airway malformation (CPAM) presented with dry cough, right-sided chest pain, and breathlessness.
Discordant pathologic response to neoadjuvant human epidermal growth factor receptor 2-directed therapy in primary breast tumour and axillary lymph node metastases.
A patient with HER2-positive breast cancer received neoadjuvant chemotherapy and HER2-directed therapy, showing significant histological response in the primary breast tumor.
Systemic light chain amyloidosis presenting as jejunal perforation.
A patient with recurrent uterine cancer presented with jejunal perforation, a rare complication of systemic light chain amyloidosis.
Phase 1 study of KHK2455, a long-acting, potent and selective IDO1 inhibitor, in combination with avelumab in patients with locally advanced or metastatic urothelial carcinoma.
This Phase 1 multicenter study assessed the safety and preliminary efficacy of KHK2455, an IDO1 inhibitor, combined with avelumab in adults with locally advanced or metastatic urothelial carcinoma.
Modified single-stapled anastomosis in laparoscopic or robotic low anterior resection for rectal cancer: protocol for a multicentre randomised controlled trial.
This multicentre, parallel-group, superiority randomised controlled trial investigates the modified single-stapled technique (MST) versus the conventional double-stapled technique (DST) in 450 patients undergoing…
Health-related quality of life with adjuvant immune checkpoint inhibition in renal cell carcinoma: A qualitative study of UK participants in the phase III RAMPART trial.
This qualitative study explored the health-related quality of life (HRQoL) impacts of adjuvant immune checkpoint inhibitors (ICIs) in renal cell carcinoma patients from the RAMPART trial.
Male breast cancer in Arab populations: a systematic review of molecular, genetic, and clinicopathologic characteristics.
This systematic review analyzed 54 studies involving 1,534 male breast cancer (MBC) patients from Arab countries, revealing that invasive ductal carcinoma is the most common subtype (92.6%).
Psychosocial interventions for children and adolescents across the cancer care continuum: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated psychosocial interventions for children and adolescents (0-19 years) with cancer, analyzing their effects on neurocognitive, psychological, and health-related quality…
Induction and concurrent aumolertinib with radiotherapy for EGFR-mutated stage III NSCLC: results of phase III ADVANCE trial and real-world validation.
The phase III ADVANCE trial evaluated a chemotherapy-free regimen of aumolertinib combined with radiotherapy in patients with unresectable stage III EGFR-mutated non-small cell lung cancer.
Optimising exercise prescription for cancer-related fatigue, lean mass, physical function and muscle strength in women with breast cancer: a systematic review with dose-response network meta-analysis.
This systematic review and dose-response network meta-analysis evaluated the effects of aerobic, resistance, and combined exercise on cancer-related fatigue, lean mass, physical function, and muscle strength in women…
Pathological complete necrosis after pulmonary thermal ablation: a systematic review and meta-analysis of ablate-and-resect studies.
This systematic review and meta-analysis examined pathological complete tumor necrosis after pulmonary thermal ablation, using eight ablate-and-resect studies comprising 95 evaluable lesions.
Association between hair cortisol concentration and cancer-related outcomes in adult patients: A systematic review.
This systematic review assessed whether hair cortisol concentration (HCC), a marker of cumulative cortisol exposure, is associated with cancer outcomes in adults with confirmed cancer.
Stroke secondary to cancer-associated coagulopathy: a systematic review.
This systematic review examined cancer-associated coagulopathy (CAC) as a cause of ischemic stroke in cancer patients, analyzing 82 studies.
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