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782 articles
July 202624
Mortality in infections caused by metallo-β-lactamase- versus serine carbapenemase-producing Enterobacterales: a systematic review and meta-analysis.
This systematic review and meta-analysis examined whether mortality differs between hospitalized adults aged ≥16 years with infections caused by metallo-β-lactamase (MBL)- versus serine β-lactamase (SBL)-producing…
Effect of probiotics on humoral responses to COVID-19 vaccination in older adults: a randomized, placebo-controlled trial (PIRATES-COV study).
This randomized controlled trial evaluated the effect of probiotics on immune responses to COVID-19 vaccination in older adults (ages 65-89) in Quebec, Canada.
Clinical and population genetic insights into primary complement component 2 (C2) deficiency: A founder variant in Ashkenazi Jews.
A 14-year-old Ashkenazi Jewish boy presented with bullous cutaneous lupus erythematosus and lupus nephritis. His diagnosis of complement component 2 deficiency (C2D) was influenced by a family history of fatal…
Pharmacokinetics and safety of TBAJ-587, a novel antimycobacterial diarylquinoline, in healthy participants.
This Phase I randomized controlled trial evaluated the pharmacokinetics and safety of TBAJ-587, a novel antimycobacterial agent, in 92 healthy adults.
Limitations of PCR-based detection of Neisseria meningitidis: The potential influence of non-encapsulated strains on diagnostic failure.
An immunocompetent patient presented with culture-positive meningococcal meningitis caused by a non-encapsulated strain. Despite the confirmed diagnosis through culture, commercially-available real-time PCR assays…
Skeletal coccidioidomycosis: an atypical pediatric presentation.
A previously healthy 12-year-old presented with 1.5 months of progressive left pelvic pain, night sweats, and weight loss, without respiratory symptoms.
Semaglutide improves MASLD and MASH in people with HIV: The SLIM LIVER study.
The SLIM LIVER study, a phase 2b open-label trial, evaluated the effects of semaglutide on metabolic dysfunction-associated steatotic liver disease (MASLD) in people with HIV.
The impact of HIV coinfection on mpox patients: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the impact of HIV coinfection on clinical outcomes in mpox patients, analyzing data from 29 studies involving 15,522 patients.
Global molecular and serological evidence of dengue and chikungunya infection: a systematic review and meta-analysis of 158,608 tested participants.
This systematic review and meta-analysis evaluated dengue virus (DENV) and chikungunya virus (CHIKV) infections in 158,608 participants across various studies.
Klebsiella pneumoniae septic pulmonary embolism from renal vein thrombosis.
A 47-year-old woman with untreated diabetes presented with urinary symptoms, fever, abdominal pain, and hypoxemia. Blood and urine cultures confirmed Klebsiella pneumoniae, with persistent bacteremia despite meropenem…
Investigation of the Resistome of non- Helicobacter pylori Helicobacter Species.
Microbiological analyses were performed on three reported human infections with non–Helicobacter pylori Helicobacter species (NHPH).
In Vitro comparison of herbal and conventional antifungals against Candida strains in Oral candidiasis: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the in vitro antifungal activity of herbal versus conventional antifungals against various Candida strains.
Tuberculosis Mimicking Tumor Progression on Dual-tracer 68Ga-DOTATATE and 18F-FDG PET/CT in Metastatic Neuroendocrine Tumor of Unknown Primary: A Potential Imaging Pitfall in Neuroendocrine Tumor Surveillance.
An elderly woman with a metastatic neuroendocrine tumor of unknown primary, who had a partial response to [177Lu]Lu-DOTATATE PRRT, presented with new hypermetabolic cervical lymph nodes on follow-up PET/CT scans.
Long-Acting Cabotegravir Injections Are More Acceptable Than Long-Acting Lenacapavir Injections After One Dose: Results From the CLARITY Randomized Crossover Study.
The CLARITY study, a randomized crossover trial involving adults without HIV, compared the acceptability of long-acting cabotegravir (CAB LA) and lenacapavir (LEN LA) injections.
Does Doxycycline Benefit Intensified Hygiene Measures in Patients with Filarial Lymphedema? A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the effects of doxycycline combined with intensified hygiene measures in patients with bancroftian filariasis.
Fatal septic shock due to PVL-positive Staphylococcus aureus necrotizing pneumonia: autopsy findings and systematic review of the literature.
A previously healthy 58-year-old man presented with acute respiratory symptoms and quickly progressed to severe respiratory failure and septic shock, leading to death within 24 hours of hospital admission.
Molecular detection of Rickettsia helvetica in lesion and blood samples after tick bites in Serbia: two cases with One Health implications.
Two cases of Rickettsia helvetica infection following tick bites were reported in Serbia. A 65-year-old woman developed pruritic erythematous lesions after being bitten by Ixodes ricinus, with R.
Chronic hepatitis E and Medicopsis romeroi coinfection in a Canadian renal transplant recipient: a case report.
A Canadian renal transplant recipient presented with chronic hepatitis E virus infection and subcutaneous phaeohyphomycosis caused by Medicopsis romeroi.
The evolution of tecovirimat resistance in an immunocompromised individual with severe mpox infection.
A 43-year-old man with advanced HIV presented with severe mpox and disseminated necrotizing disease. Despite prolonged treatment with tecovirimat, his lesions worsened.
Retroperitoneal infection associated with Streptococcus dysgalactiae subsp. equisimilis bacteremia and lower-extremity cellulitis: a case report.
A 70-year-old man with diabetes and alcoholic liver disease presented with fever and septic shock. Initial imaging revealed retroperitoneal lymphadenopathy and inflammatory changes, with subsequent identification of…
Worldwide Seroprevalence and Risk Factors of Toxoplasma gondii Exposure Among Students: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed the global seroprevalence of Toxoplasma gondii among students, analyzing data from 50 studies involving 32,054 participants across 24 countries.
Efficacy and safety of oral type II topoisomerase inhibitors versus ceftriaxone-based regimens for the treatment of gonorrhoea: A systematic review and meta-analysis of randomised controlled trials.
This systematic review and meta-analysis evaluated the efficacy and safety of oral type II topoisomerase inhibitors, gepotidacin and zoliflodacin, compared to ceftriaxone for treating uncomplicated gonorrhoea.
Lymph Node Cytology Raising Suspicion for Evolving Secondary Hemophagocytic Lymphohistiocytosis in a Case of Mendelian Susceptibility to Mycobacterial Disease.
A 4-month-old male infant with genetically confirmed Mendelian susceptibility to mycobacterial disease presented at 22 months with generalized lymphadenopathy, massive splenomegaly, bicytopenia, and high-grade fever.
Pharmacokinetics of injectable favipiravir: phase I, randomized, double-blind, placebo-controlled study in healthy East Asian subjects.
This phase I, randomized, double-blind, placebo-controlled trial evaluated the pharmacokinetics and tolerability of injectable favipiravir in healthy East Asian subjects.
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