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60 articles

September 20266

Clinical ResearchFamily MedicineOpen access

Toward personalized interventions for preventing depression in primary care: Qualitative and quantitative findings from the e-predictD pilot study.

The e-predictD pilot study evaluated a personalized intervention for preventing depression in primary care, involving 56 non-depressed patients at moderate-to-high risk.

PLoS OneSep 11, 2026Read summary
Clinical ResearchGastroenterology

Optimization strategies for care‑giving behaviors of family caregivers for patients with enterostomy: An evidence summary.

This systematic review summarizes evidence on optimizing caregiving behaviors for family caregivers of patients with enterostomy.

PLoS OneSep 10, 2026Read summary
Clinical ResearchPsychiatryOpen access

Barriers and facilitators to the implementation of pharmacogenomic testing for antidepressants use in primary care: a systematic review using the consolidated framework for implementation research.

This systematic review examined barriers and facilitators to implementing pharmacogenomic (PGx) testing for antidepressant use in primary care, utilizing the Consolidated Framework for Implementation Research (CFIR).

Pharmacogenomics JSep 9, 2026Read summary
Clinical ResearchFamily Medicine

Does physician familiarity enhance video-based lifestyle counseling in adults with overweight or obesity? A randomized controlled trial.

This multicenter randomized controlled trial investigated the impact of physician familiarity on video-based lifestyle counseling effectiveness in 115 adults with overweight or class I obesity.

Patient Educ CounsSep 7, 2026Read summary
Case ReportEndocrinology

Primary Care Recognition of Rabson-Mendenhall Syndrome Despite Absence of Classical Diabetic Symptoms.

A 10-year-old girl presented with intermittent bilateral leg pain and excessive hunger, lacking classical diabetic symptoms. Examination revealed extensive acanthosis nigricans, moderate hirsutism, and dental defects.

Am J Case RepSep 5, 2026Read case
Clinical ResearchInfectious DiseasesOpen access

Implementation, adoption and impact of clinical decision support system for antibiotic prescribing in primary care: a systematic review.

This systematic review evaluated the implementation and impact of clinical decision support systems (CDSS) for antibiotic prescribing in primary care, analyzing 40 studies.

J Antimicrob ChemotherSep 1, 2026Read summary

August 20261

July 20268

Clinical ResearchFamily MedicineOpen access

Factors influencing deprescribing in community-dwelling patients with palliative needs in primary care: A qualitative systematic review.

This qualitative systematic review examined factors influencing deprescribing in community-dwelling patients with palliative needs in primary care.

Palliat MedJul 31, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Finding Balance: Insights from Mexican Heritage Families on Living a Healthy Lifestyle in New York City.

This clinical trial explored the perspectives of 31 Hispanic parents/caregivers with overweight or obesity in New York City regarding healthy lifestyle interventions.

J Community HealthJul 23, 2026Read summary
Clinical ResearchPsychiatry

Functional disability after critical illness in patients with post-traumatic stress disorder symptoms in primary care: A secondary analysis of the PICTURE randomized controlled trial.

This secondary analysis of the PICTURE randomized controlled trial examined disability in 319 adults with PTSD symptoms at least 3 months after ICU discharge and assessed change after brief GP-led trauma-focused care…

J Psychosom ResJul 22, 2026Read summary
Case ReportGeriatrics

Impact of a nursing intervention on frailty in people aged 65-75 years in primary care. A pilot clinical trial.

To analyse whether an intervention carried out by primary care nurses modifies the degree of frailty in people between 65 and 75 years of age.

Enferm Clin (Engl Ed)Jul 20, 2026Read case
Clinical ResearchObstetrics & GynecologyOpen access

Effect of Music on Pain, Anxiety, and Satisfaction During Intrauterine Device Application: A Randomized Clinical Trial.

This randomized controlled trial investigated the impact of music on pain, anxiety, and satisfaction during intrauterine device (IUD) insertion in 70 women.

Res Nurs HealthJul 16, 2026Read summary
Clinical ResearchPediatricsOpen access

Effectiveness of Family-Focused End of Life and Bereavement Interventions Across Neonatal, Paediatric, and Adult Intensive Care: An Overview of Reviews.

This overview of reviews examined the effectiveness of family-focused end-of-life and bereavement interventions in neonatal, paediatric, and adult ICUs.

J Clin NursJul 14, 2026Read summary
Clinical ResearchEndocrinology

How Families Influence Self-Management Among the Role of Family to Patients With Type 2 Diabetes? A Systematic Review and Meta-Synthesis.

This systematic review and meta-synthesis examined qualitative and mixed-methods research on how families influence self-management among people with type 2 diabetes.

J Adv NursJul 11, 2026Read summary
Clinical ResearchInternal Medicine (General)

System failures in care continuity and coordination for people with multiple long-term conditions: an umbrella review of patient, carer, and professional perspectives.

This umbrella review examined continuity and coordination of care for patients with multiple long-term conditions (MLTCs) from the perspectives of patients, carers, and healthcare professionals.

Health PolicyJul 9, 2026Read summary

June 20265

Clinical ResearchObstetrics & Gynecology

Experiences of stigma, bias, and communication challenges among pregnant healthcare workers: A systematic review of qualitative evidence.

This systematic review synthesizes qualitative evidence on stigma, bias, and communication challenges faced by pregnant healthcare workers across 14 studies involving 1223 participants from 17 countries.

Int J Nurs StudJun 30, 2026Read summary
Clinical ResearchInternal Medicine (General)

Collaborative care intervention for risky opioid use among primary care patients: The STOP randomized clinical trial.

The STOP randomized controlled trial evaluated a collaborative care intervention aimed at reducing risky opioid use among primary care patients. Conducted across five U.S.

AddictionJun 22, 2026Read summary
Clinical ResearchGeriatrics

Experiences and needs of informal caregivers for respite care: A mixed-methods systematic review.

This mixed-methods systematic review examined the experiences and needs of informal caregivers regarding respite care, synthesizing data from 33 studies.

Geriatr NursJun 14, 2026Read summary
Clinical ResearchEndocrinology

Does heat affect the performance of bioceramic sealers? A systematic review of warm obturation.

This systematic review assessed how heat used in warm obturation affects bioceramic sealers in endodontic treatment. It identified 12 relevant studies examining bond strength, physicochemical properties, and clinical…

Minerva Dent Oral SciJun 11, 2026Read summary
Clinical ResearchPsychiatryOpen access

A pilot randomized clinical trial evaluating the feasibility, acceptability, and preliminary efficacy of a cognitive-behavioral therapy adjunct to support benzodiazepine tapering among primary care patients coprescribed benzodiazepines and opioids.

This pilot randomized clinical trial evaluated the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy (CBT) as an adjunct to benzodiazepine tapering in adults prescribed both…

Psychol Addict BehavJun 8, 2026Read summary

May 20264

Clinical ResearchFamily Medicine

Effectiveness of Telemedicine-Based Interventions in Primary Health Care: A Systematic Review in a Universal Health System.

This systematic review evaluated the effectiveness of telemedicine-based interventions in primary health care (PHC) across 22 studies.

Telemed J E HealthMay 27, 2026Read summary
Clinical ResearchInternal Medicine (General)

Interventions that strengthen the patient-clinician relationship improve healthcare outcomes: An updated systematic review and meta-analysis.

This systematic review and meta-analysis evaluated clinician-focused interventions aimed at strengthening patient-clinician relationships across 28 randomized controlled trials involving 18,046 patients.

Patient Educ CounsMay 20, 2026Read summary
Clinical ResearchGeriatrics

Efficacy and Implementation of a Theory-Underpinning Needs-Oriented mHealth Supportive Program for Family Caregivers of Community-Dwelling Frail Older Adults (Hi-Care): A Randomized Controlled Trial.

This randomized controlled trial evaluated the Hi-Care mHealth program for family caregivers of community-dwelling frail older adults.

Am J Geriatr PsychiatryMay 20, 2026Read summary
Clinical ResearchPsychiatryOpen access

Evaluating the Effectiveness of an Intimate Partner Violence Training Intervention on Healthcare Providers' Preparedness, Knowledge, and Experiences: A Mixed-Methods Study From Nepal.

This randomized controlled trial in Nepal assessed the effectiveness of a 10-day training intervention on healthcare providers' preparedness and knowledge regarding intimate partner violence (IPV).

J Interpers ViolenceMay 19, 2026Read summary

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