Trending archive
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782 articles
July 20268
Vitamin D Deficiency and Severe Dengue Fever: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined the relationship between vitamin D deficiency and severe dengue fever across six studies involving 1,130 participants.
Chronic prosthetic joint infection caused by Coxiella burnetii diagnosed by metagenomic next-generation sequencing: A case report and literature review.
A patient with a history of joint arthroplasty presented with persistent joint pain and swelling due to a prosthetic joint infection.
Identification of risk factors for hospital-onset bacteraemia to inform a routine data based risk prediction: an umbrella review.
This umbrella review identified and classified risk factors for hospital-onset bacteraemia (HOB) in OECD countries. The study synthesized evidence from 19 systematic reviews, revealing 43 risk factors, including prior…
Healthcare-associated infections in the Middle East: a systematic review and meta-analysis of point-prevalence studies.
This systematic review and meta-analysis examined the point prevalence of hospital-acquired infections (HAIs) among hospitalized patients in the Middle East.
Phone-based screening versus home-based screening after tuberculosis in India (TB Aftermath): a multicentre, open-label, randomised, controlled, non-inferiority trial.
This multicentre, open-label, randomised non-inferiority trial compared phone-based with home-based symptom screening after tuberculosis treatment in survivors and their household contacts in Maharashtra, India.
Aspergillus prosthetic valve endocarditis complicated by intracranial haemorrhage.
A 73-year-old male presented with early prosthetic aortic valve endocarditis 45 days post valve replacement, complicated by intracranial hemorrhage.
Diagnostic accuracy of tests for visceral leishmaniasis caused by Leishmania infantum: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the diagnostic accuracy of tests for visceral leishmaniasis (VL) caused by Leishmania infantum in individuals with suspected disease, including those with HIV.
Occupational Mpox in personal protective equipment-compliant registered nurse reinforces importance of CDC 21-day self-monitoring after patient care.
A registered nurse developed laboratory-confirmed mpox despite following strict personal protective equipment protocols while caring for a suspected patient.
June 202616
Phase 1 trial of intranasal NDV-HXP-S in previously vaccinated adults.
This Phase 1 randomized controlled trial evaluated the safety and immunogenicity of intranasal NDV-HXP-S in 35 previously vaccinated adults. The vaccine was well tolerated, with only grade 1-2 adverse events reported.
Effect of malaria parasitaemia on antibody responses to single-dose and two-dose HPV vaccination: results from the DoRIS dose-reduction immunogenicity trial in Tanzanian girls.
This randomized controlled trial evaluated the impact of malaria parasitaemia on HPV vaccine immune responses in 930 HIV-negative Tanzanian schoolgirls aged 9-14 years.
Estimates of sexually transmitted infection prevalence and prevalence ratio among international migrants compared with non-migrants: A global systematic review and meta-analysis.
This systematic review and meta-analysis examined the prevalence of sexually transmitted infections (STIs) among international migrants compared to non-migrants, analyzing data from 85 studies across 31 countries.
Community-engaged implementation strategies to increase doxycycline post-exposure prophylaxis uptake among men who have sex with men in China (DoxyForward): a three-group, open-label, randomised controlled trial.
DoxyForward was a three-group, open-label randomised controlled trial at community-based organisations in seven Chinese provinces, testing community-engaged strategies to increase doxycycline post-exposure prophylaxis…
Efficacy, safety, and immunogenicity of an Escherichia coli-produced nine-valent human papillomavirus vaccine: a multicentre, double-blind, randomised, controlled, phase 3 trial.
This multicentre, double-blind, randomised phase 3 trial compared an Escherichia coli-produced nine-valent HPV vaccine with a bivalent vaccine in healthy, unvaccinated women aged 18–45 years in China.
Efficacy of WRSs2, a live-attenuated Shigella sonnei vaccine, against shigellosis in a controlled human infection model in the USA: a phase 2, double-blind, randomised, placebo-controlled trial.
This phase 2, double-blind, randomised, placebo-controlled trial assessed the safety and efficacy of live-attenuated Shigella sonnei vaccine WRSs2 in healthy US adults aged 18–49 years using a controlled human infection…
The Brief case: Misidentification of Cardiobacterium valvarum as Biosafety Level 3 organism Francisella tularensis by VITEK® automated system and diagnostic approach using a "rule out or refer" algorithm.
A bacterial isolate initially misidentified as Francisella tularensis by the VITEK® automated system was ultimately confirmed to be Cardiobacterium valvarum.
Effectiveness of interventions to promote couples-based HIV testing and family health during pregnancy and postpartum in Kenya: a multicentre, couples-based, randomised controlled trial.
This multicentre, couples-based, randomised controlled trial in Kenya evaluated the effectiveness of two interventions—home visits and HIV self-testing kits—on couples' HIV testing uptake and maternal and child health…
Dengue epidemic in Northern Peru (2024): analysis of 2,449 cases.
During the 2024 dengue epidemic in northern Peru, a retrospective analysis of 2,449 confirmed cases revealed that 54.4% had dengue without warning signs, 45.0% had dengue with warning signs, and 0.7% had severe dengue.
Dolutegravir improves physical health-related quality of life in adults with HTLV-1 infection: A randomized controlled trial.
This randomized controlled trial evaluated the impact of dolutegravir on health-related quality of life (HRQoL) in adults with HTLV-1 infection over 96 weeks.
The benefit of physical exercise in improving quality of life, VO 2 max and sleep quality among older adults living with HIV: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of physical exercise on quality of life, VO₂ max, and sleep quality in older adults living with HIV.
Tularemia-associated septic shock with pneumonia, lung abscesses, and pleural effusion leading to multiorgan failure: Is Francisella tularensis still a deadly pathogen in the antibiotic era? A case report.
A patient with pulmonary tularemia presented with septic shock, lung abscesses, and pleural effusion, leading to multiorgan failure.
Ceftaroline pharmacokinetics on ECMO, a pediatric case report.
A 5-year-old patient on ECMO for influenza-associated necrotizing pneumonia was analyzed for ceftaroline pharmacokinetics. Nine concentrations were measured, revealing minimal changes in volume of distribution and…
Human septic arthritis caused by Spiroplasma turonicum.
An immunocompromised patient in France presented with septic arthritis of the wrist. Diagnosis was achieved through molecular analysis, with whole-genome sequencing confirming Spiroplasma turonicum as the causative…
Congenital dengue with detection of viral RNA in cerebrospinal fluid: A case report.
A 35-week preterm newborn presented with fever and hyporesponsiveness on day seven of life, following maternal dengue infection. Diagnostic testing revealed dengue virus RNA in both serum and cerebrospinal fluid.
Comparative efficacy and safety of colistin-based and alternative antibiotic regimens for multidrug-resistant Gram-negative infections: A systematic review and network meta-analysis.
This systematic review and network meta-analysis evaluated the efficacy and safety of colistin-based regimens versus alternative antibiotics for multidrug-resistant Gram-negative infections in 1760 patients.
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