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785 articles
June 202624
Clinical Efficacy of Sacral Neuromodulation for Fecal Incontinence Across Multiple Etiologies: A Single-Center Study.
This retrospective study evaluated the efficacy of sacral neuromodulation (SNM) for fecal incontinence (FI) in 34 patients with various etiologies.
Sex differences in the association between air pollution and obesity: a systematic review and meta-analysis.
This systematic review and meta-analysis examined sex-specific associations between air pollution and obesity in approximately 800,000 adults.
Hepatic Safety of Orforglipron in Adults With Obesity or Overweight and/or Type 2 Diabetes: A Pooled Analysis of the Orforglipron Phase 3 Clinical Trials.
This pooled analysis of seven Phase 3 clinical trials evaluated the hepatic safety of orforglipron in 11,220 adults with obesity or type 2 diabetes.
99m Tc-FAPI SPECT/CT Provides Superior Diagnostic Performance to 18 F-FDG in Poorly Differentiated Gastric Adenocarcinoma.
A 52-year-old woman with poorly differentiated gastric adenocarcinoma experienced early satiety following gastrectomy and chemotherapy. Initial imaging with CT and FDG PET/CT did not clearly indicate recurrence.
Assessment of in-hospital mortality in patients with upper gastrointestinal bleeding on antithrombotic treatment.
This systematic review and meta-analysis evaluated the impact of antithrombotic therapy on in-hospital mortality in patients with upper gastrointestinal bleeding.
Efficacy and hepatotoxicity of Psoralea corylifolia L.: A meta-analysis and machine learning assessment in postmenopausal osteoporosis.
This meta-analysis evaluated the efficacy and hepatotoxicity of Psoralea corylifolia in postmenopausal osteoporosis. It included 23 efficacy studies and 7 toxicity studies, revealing a significant improvement in bone…
Pre-Emptive Initiation of Continuous Renal Replacement Therapy in Patients With Acute Liver Failure With Cerebral Edema Improves Outcomes: A Randomized Controlled Trial.
This randomized controlled trial investigated the effects of early continuous renal replacement therapy (CRRT) initiation in patients with acute liver failure (ALF) and cerebral edema (CE).
Impact of weight loss and reduction of ultra-processed foods on liver fat content in MASLD: A randomized controlled trial.
This randomized controlled trial investigated the effects of different dietary strategies on liver fat content in patients with metabolic dysfunction-associated steatotic liver disease (MASLD).
Comparing the diagnostic performance of 19-gauge and 22-gauge needles in endoscopic ultrasound-guided liver biopsy: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the diagnostic performance of 19-gauge (G) versus 22-G needles in endoscopic ultrasound-guided liver biopsy (EUS-LB).
Computer-assisted versus standard colonoscopy for adenoma detection in a population-based colorectal cancer screening program: a randomized clinical trial.
This multicenter randomized clinical trial evaluated the impact of computer-aided detection (CADe) systems on adenoma detection rates (ADR) in patients aged 40-79 undergoing colonoscopy after a positive fecal…
Effects of Incretin-Based Therapies, Diet and Exercise Interventions, and Bariatric Surgery on Fat-Free Mass in Adults With Overweight or Obesity: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the impact of various weight-loss modalities on fat-free mass (FFM) in adults with overweight or obesity.
Multidisciplinary treatment with durvalumab-containing regimens for mixed neuroendocrine-non-neuroendocrine neoplasm of the extrahepatic bile duct.
A 63-year-old man presented with jaundice and a bile duct tumor involving the perihilar-to-distal extrahepatic duct, with bulky lymph node metastases. Initial biopsy showed adenocarcinoma.
Methods to build and maintain effective clinician-patient relationships for adults with disorders of gut-brain interaction (DGBI): a systematic review.
This systematic review examined methods for building and maintaining effective clinician–patient relationships in adults receiving care for disorders of gut-brain interaction (DGBI).
Eating competence trajectories of persons with metabolic syndrome over two years: A secondary analysis of the ELM lifestyle intervention.
This secondary analysis of the ELM lifestyle intervention, a randomized controlled trial, evaluated eating competence (EatC) trajectories in individuals with metabolic syndrome (MetS) over two years.
Quality of Life Endpoints in Advanced Gastrointestinal Cancer Trials: Systematic Review of Inclusion, Challenges, and Implications (2020-2024).
This systematic review examined the inclusion of quality of life (QoL) endpoints in 80 phase III clinical trials for advanced gastrointestinal cancers.
Multi-herb formulations modulating gut microbiota: A systematic review and data-driven analysis.
This systematic review analyzed 29 clinical trials involving 954 participants to assess how multi-herb formulations affect gut microbiota.
Efficacy and safety of JAK inhibitors in Behçet syndrome: systematic literature review.
This systematic literature review evaluated the efficacy and safety of JAK inhibitors in 92 patients with Behçet syndrome. The study found that JAK inhibitors achieved remission rates of 85.9% overall, with specific…
Use of mesoglycan in the acute phase of hemorrhoidal disease, the aCute HaemORrhoidal MEsoglycan Study (CHORMES): A double-blind, randomized controlled trial.
The aCute HaemORrhoidal MEsoglycan Study was a double-blind, randomized controlled trial assessing mesoglycan's efficacy in adults with symptomatic grade II to III hemorrhoidal disease.
The impact of (poly)phenol-rich sugarcane extract intervention on markers of gastrointestinal integrity and systemic inflammation in response to exertional-heat stress.
This randomized controlled trial investigated the effects of a (poly)phenol-rich sugarcane extract (PRSE) on gastrointestinal integrity and systemic inflammation during exertional-heat stress (EHS) in 14 participants.
Probiotic, prebiotic, and synbiotic interventions targeting the early-life gut-brain axis: A systematic review of randomized controlled trials.
This systematic review evaluated randomized controlled trials assessing probiotic, prebiotic, and synbiotic interventions in infants aged 0-36 months, focusing on their effects on gut-brain axis biomarkers.
Short-Term Versus Long-Term Efficacy of Endoscopic Sleeve Gastroplasty in 8880 Obese Patients: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the efficacy of endoscopic sleeve gastroplasty (ESG) in 8880 obese patients, focusing on weight loss and metabolic outcomes over short- and long-term follow-up.
Performance of Survival Prediction Tools in Patients With Gastrointestinal Stromal Tumors: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated survival prediction tools for adults with primary gastrointestinal stromal tumors (GISTs), analyzing 47 studies.
Incidence of Cirrhosis in Fibrotic Metabolic Dysfunction-Associated Steatohepatitis: A Meta-Analysis of Placebo Arms from Randomized Clinical Trials.
This meta-analysis evaluated the incidence of cirrhosis in placebo-treated patients with fibrotic metabolic dysfunction-associated steatohepatitis (MASH) across 11 randomized controlled trials.
Comparative Efficacy of Insulin and Alternative Therapies for Hypertriglyceridemia-Associated Acute Pancreatitis: A Systematic Review and Network Meta-Analysis.
This systematic review and network meta-analysis evaluated the efficacy of insulin and alternative therapies for hypertriglyceridemia-associated acute pancreatitis.
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