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1034 articles

July 20266

Clinical ResearchNeurology

Gut microbiota alterations in Alzheimer's disease and mild cognitive impairment: A systematic review and meta-analysis.

This systematic review and meta-analysis examined gut microbiota differences in older adults with Alzheimer's disease (AD) and mild cognitive impairment (MCI) compared to cognitively normal (CN) controls.

J Alzheimers DisJul 2, 2026Read summary
Clinical ResearchOncology (Medical)

Temozolomide Versus Radiotherapy as First-Line Therapy for Low-Grade Glioma: Mature Results of a Randomized Phase III Trial (EORTC 22033-26033/NCIC-CTG/TROG/MRC-CTU).

This multicenter, randomized phase III trial compared first-line radiotherapy with dose-dense temozolomide in 478 patients with clinically high-risk WHO grade 2 low-grade glioma.

J Clin OncolJul 2, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

The effectiveness of artificial intelligence-based interventions on treatment outcomes for low back pain: A systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis of randomized controlled trials assessed artificial intelligence-based interventions versus standard interventions for pain and functional outcomes in adults with low back pain.

J Back Musculoskelet RehabilJul 2, 2026Read summary
Clinical ResearchOncology (Medical)

Neuroprotection and prevention of oxaliplatin-induced neuropathy with Huangqi Guizhi Wuwu Decoction: a 12-center randomized, double-blind trial with mechanistic validation.

This multicenter, randomized, double-blind trial evaluated the efficacy of Huangqi Guizhi Wuwu Decoction (HQGZWWD) in preventing oxaliplatin-induced peripheral neuropathy (OIPN) in 360 adults with colorectal cancer…

PhytomedicineJul 1, 2026Read summary
Clinical ResearchNeurology

ENTF Neuromodulation Yields Reduced Disability After Stroke: An Individual Participant-Level Data Meta-Analysis.

This meta-analysis pooled individual participant data from two randomized, sham-controlled trials to evaluate the efficacy of electromagnetic network-targeted field (ENTF) brain stimulation in reducing post-stroke…

StrokeJul 1, 2026Read summary
Clinical ResearchPediatrics

Blood-Based Biomarkers Predict Cerebral Palsy and Cognitive Delay in Hypoxic-Ischemic Encephalopathy: A Secondary Analysis of the High-Dose Erythropoietin for Asphyxia and Encephalopathy Randomized Controlled Trial.

This secondary analysis of a randomized controlled trial evaluated blood-based biomarkers in 180 infants with moderate-severe hypoxic-ischemic encephalopathy (HIE) to predict cerebral palsy (CP) and cognitive/language…

J PediatrJul 1, 2026Read summary

June 202618

Clinical ResearchNeurologyOpen access

Usability and Acceptance of Autoinjector and Prefilled Syringe Devices by Patients with Generalized Myasthenia Gravis in a Human Factors Study.

This randomized controlled trial evaluated the usability and acceptance of a prefilled syringe with needle safety device (PFS-SD) and an autoinjector (AI) among patients with generalized myasthenia gravis (gMG).

Adv TherJun 30, 2026Read summary
Clinical ResearchPediatrics

Cerebral, spinal, ophthalmological and skeletal findings associated with abusive and non-abusive head injury in children under 2 years old: A systematic review.

This systematic review examined differences in clinical findings between children under 2 years with abusive head trauma (AHT) and non-abusive head trauma (nAHT).

Child Abuse NeglJun 30, 2026Read summary
Clinical ResearchNeurology

Serum angiogenesis-hypoxia biomarkers in relapsing-remitting multiple sclerosis.

This randomized controlled trial investigated serum angiogenesis and hypoxia biomarkers in 122 participants with relapsing-remitting multiple sclerosis (RRMS) compared to 78 healthy controls.

Mult Scler Relat DisordJun 29, 2026Read summary
Clinical ResearchNeurology

Effects of physical exercise on neurofilament light chain in multiple sclerosis and other neurological disorders: A systematic review.

This systematic review evaluated the effects of physical exercise on neurofilament light chain (NfL) levels in individuals with multiple sclerosis (MS) and other neurological disorders.

Mult Scler Relat DisordJun 29, 2026Read summary
Clinical ResearchNeurology

The Effect of Intravascular Laser Irradiation of Blood in Functional Outcomes of Ischemic Stroke Patients: A Double-Blind Randomized Control Pilot Study.

This double-blind randomized controlled pilot study evaluated the efficacy of intravenous laser irradiation of blood (ILIB) therapy in 22 patients with ischemic stroke.

Photobiomodul Photomed Laser SurgJun 29, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Efficacy of pharyngeal balloon muscle resistance treatment in post-stroke dysphagia: A randomized controlled trial.

This randomized controlled trial evaluated the efficacy of Pharyngeal Balloon Muscle Resistance Treatment (PBMRT) in 60 post-stroke patients with dysphagia.

J Stroke Cerebrovasc DisJun 29, 2026Read summary
Clinical ResearchGeriatrics

Diet and Cognitive Function in Aging: An Individual Participant Data Meta-Analysis from 8 Cohorts in Europe and the United States.

This meta-analysis examined the relationship between dietary patterns and cognitive function in 17,368 participants from 8 cohorts in Europe and the US.

J NutrJun 29, 2026Read summary
Case ReportOncology (Medical)

Epileptogenic Brain Metastasis Early Positive on 18 FDG PET/CT Compared to MRI.

A 61-year-old woman with metastatic small cell lung carcinoma presented with a persistent tremor in her right upper limb. Initial brain MRI results were normal, but 18 F-FDG PET/CT revealed hypermetabolism in the left…

Clin Nucl MedJun 29, 2026Read case
Case ReportPediatrics

Dural Manifestation of Langerhans Cell Histiocytosis​: Multimodality Imaging Approach.

A 2-year-old boy presented with scalp swelling, leading to the diagnosis of Langerhans cell histiocytosis (LCH) with dural involvement.

Clin Nucl MedJun 29, 2026Read case
Clinical ResearchNeurology

Predicting cognitive function in Alzheimer's clinical trials via amyloid β-protein biomarkers.

This meta-analysis examined the relationship between amyloid-β biomarkers and cognitive outcomes in Alzheimer's clinical trials, analyzing data from 57 studies involving 93,417 subjects.

Br J Clin PharmacolJun 28, 2026Read summary
Clinical ResearchNeurology

Modulating sentence comprehension in people with aphasia through anodal tDCS: A double-blind randomized cross-over study.

This double-blind randomized cross-over study examined the impact of anodal transcranial direct current stimulation (AtDCS) combined with speech-language therapy on sentence comprehension in eight individuals with…

NeuropsychologiaJun 27, 2026Read summary
Clinical ResearchNeurology

Clinical features, imaging findings, and treatment outcomes of optic neuritis associated with anti-CRMP5 antibodies: a systematic review.

This systematic review analyzed 32 patients with optic neuritis associated with anti-CRMP5 antibodies. The study found that 87.1% had bilateral optic neuritis, with 64% experiencing visual acuity worse than 20/200.

J NeuroimmunolJun 27, 2026Read summary
Case ReportNeurology

Bridging to low-dose corticosteroids after satralizumab discontinuation in unplanned pregnancy: Two cases of AQP4-positive NMOSD.

Two patients with AQP4-positive neuromyelitis optica spectrum disorder (NMOSD) experienced unplanned pregnancies while on satralizumab.

Mult Scler Relat DisordJun 27, 2026Read case
Clinical ResearchGeriatrics

Association of vegetable and fruit intake with risk of dementia: 3 prospective studies and meta-analysis of cohort studies.

This meta-analysis examined the relationship between vegetable and fruit intake and dementia risk across three prospective cohorts, involving 18,339 participants aged ≥45 years.

Am J Clin NutrJun 27, 2026Read summary
Clinical ResearchCardiology

The co-existence of Ehlers-Danlos syndrome and postural orthostatic tachycardia syndrome: A systematic review of the literature.

This systematic review evaluated the co-existence of Ehlers-Danlos syndrome (EDS) and postural orthostatic tachycardia syndrome (POTS) across 30 studies involving 8421 EDS patients and 12,983 POTS patients.

Auton NeurosciJun 27, 2026Read summary
Clinical ResearchNeurology

Effects of transcutaneous auricular nerve stimulation on thalamic relay: A randomized brain imaging study in chronic low back pain patients.

This randomized controlled trial examined the effects of transcutaneous auricular vagus nerve stimulation (taVNS) and transcutaneous greater auricular nerve stimulation (tGANS) on thalamocortical circuits in 70 patients…

Brain ResJun 26, 2026Read summary
Clinical ResearchNeurology

Real-time EEG-based epileptic seizure prediction using artificial intelligence: A systematic review.

This systematic review assessed the readiness of AI models for real-time epileptic seizure prediction, analyzing 23 studies.

Artif Intell MedJun 26, 2026Read summary
Clinical ResearchNeurology

Exploring the prognostic value of resting state brain activity in Disorders of Consciousness: A coordinate-based meta-analysis.

This meta-analysis examined the prognostic value of resting state brain activity in 332 patients with Disorders of Consciousness (DoC).

Neurosci Biobehav RevJun 26, 2026Read summary

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