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962 articles

May 202624

Clinical ResearchCardiology

Traditional left ventricular indices outperform novel cardiovascular magnetic resonance-derived left atrial parameters in predicting adverse left ventricular remodelling after ST-segment elevation myocardial infarction.

This randomized controlled trial analyzed 200 patients with anterior ST-segment elevation myocardial infarction (STEMI) to evaluate the prognostic significance of left ventricular (LV) global longitudinal strain (GLS)…

Int J CardiolMay 25, 2026Read summary
Clinical ResearchNephrology

Effect of catheter-based renal denervation on orthostatic blood pressure adaptation in patients with uncontrolled hypertension.

This randomized controlled trial assessed the impact of catheter-based renal denervation (RDN) on orthostatic blood pressure adaptation in patients with uncontrolled hypertension.

J CardiolMay 25, 2026Read summary
Clinical ResearchCardiology

Dosing of single-shot pulsed field ablation systems: A systematic review of efficacy and safety balance.

This systematic review evaluated the efficacy and safety of single-shot pulsed field ablation (PFA) systems for pulmonary vein isolation in atrial fibrillation, analyzing 47 primary studies.

Heart RhythmMay 25, 2026Read summary
Clinical ResearchCardiology

A Bayesian re-analysis of hypothermic oxygenated perfusion versus static cold storage in the NIHP2019 heart transplantation trial.

This Bayesian re-analysis of the NIHP2019 heart transplantation trial compared hypothermic oxygenated perfusion (HOPE) to static cold storage (SCS) in 204 patients.

J Heart Lung TransplantMay 25, 2026Read summary
Clinical ResearchCardiologyOpen access

Acute myocardial mechanical responses to colloid and crystalloid volume loading: A randomized double-blind crossover study.

This randomized double-blind crossover trial investigated myocardial mechanical responses to colloid (Gelafundin 4%) versus crystalloid (0.9% sodium chloride) volume loading in 20 healthy volunteers.

Br J Clin PharmacolMay 25, 2026Read summary
Clinical ResearchCardiology

Does a Digital Prehabilitation Solution Informed by Evidence-Based Interventions Reduce the Healthcare Burden and Improve Outcomes for Patients Awaiting Cardiac Surgery?-A Systematic Review.

This systematic review evaluated the effectiveness of digital prehabilitation for adults awaiting cardiac surgery. It found that digital prehabilitation significantly improves feasibility, efficacy, complications, and…

Heart Lung CircMay 23, 2026Read summary
Clinical ResearchCardiology

A systematic review of acute and long-term outcomes in patients with non-transvenous implantable cardioverter-defibrillators.

This systematic review evaluated the outcomes of non-transvenous implantable cardioverter-defibrillators (ICDs) in adult patients with guideline-based indications.

J Med EconMay 22, 2026Read summary
Clinical ResearchCardiology

Pre-perfusion coronary wedge pressure and microvascular obstruction in anterior ST elevation myocardial infarction (STEMI): An analysis from the EUROICE study.

This randomized controlled trial analyzed the relationship between pre-reperfusion coronary wedge pressure (CWP) and microvascular obstruction (MVO) in 82 anterior STEMI patients treated with selective intracoronary…

Int J CardiolMay 22, 2026Read summary
Clinical ResearchCardiologyOpen access

Opioid-free Anesthesia in Cardiac Surgery: The OFACAR Randomized Clinical Trial.

The OFACAR trial was a randomized, controlled, multicenter study involving 320 adults undergoing elective cardiac surgery. It compared opioid-free anesthesia (OFA) to opioid anesthesia.

AnesthesiologyMay 22, 2026Read summary
Clinical ResearchCardiology

Advancing stroke prevention in atrial fibrillation: a systematic review of machine learning-based risk prediction models.

This systematic review evaluated machine learning (ML) models for predicting ischemic stroke in patients with atrial fibrillation (AF) using electronic health record data.

Int J Med InformMay 22, 2026Read summary
Clinical ResearchCardiology

A systematic review and meta-analysis of elevated lipoprotein(a) and adverse limb outcomes in peripheral artery disease after revascularization.

This systematic review and meta-analysis evaluated the relationship between elevated lipoprotein(a) [Lp(a)] levels and peripheral artery disease (PAD) outcomes post-revascularization.

J Vasc SurgMay 22, 2026Read summary
Clinical ResearchCardiologyOpen access

Pacing-Induced Cardiomyopathy in Leadless and Transvenous Pacemakers: A Meta-Analysis and Meta-Regression.

This meta-analysis evaluated the prevalence of pacing-induced cardiomyopathy (PICM) in 3224 patients with leadless pacemakers compared to transvenous systems.

Pacing Clin ElectrophysiolMay 22, 2026Read summary
Case ReportEndocrinology

Atrial fibrillation as the initial presentation of hyperthyroidism: Two cases: Graves' thyroid storm and toxic adenoma.

Two patients presented with new-onset atrial fibrillation (AF) as the initial manifestation of hyperthyroidism. The first case involved rapid AF due to Graves' disease, while the second case was attributed to a solitary…

Trop DoctMay 22, 2026Read case
Clinical ResearchCardiologyOpen access

Safety, tolerability, and pharmacokinetics/-dynamics of the dipeptidyl peptidase 3-inhibiting antibody Procizumab in a first-in-human trial.

This Phase 1 randomized controlled trial evaluated the safety, tolerability, and pharmacokinetics of Procizumab (PCZ), a DPP3-inhibiting antibody, in 24 healthy male volunteers.

MAbsMay 21, 2026Read summary
Clinical ResearchEndocrinology

Acute and chronic effects of mixed nuts on energy metabolism in women at cardiometabolic risk: a randomized clinical trial.

This randomized controlled trial evaluated the effects of mixed nuts on energy metabolism in women with overweight/obesity.

Nutr Metab Cardiovasc DisMay 21, 2026Read summary
Case ReportAllergy & Immunology

Eosinophilic vasculitis of aortic valve in EGPA: a life-threatening onset of disease.

A 51-year-old man with eosinophilic severe asthma and chronic rhinosinusitis presented with worsening dyspnea and cardiac arrest after two months of low-grade fever and malaise.

J AsthmaMay 21, 2026Read case
Clinical ResearchCardiology

Progression of persistent atrial fibrillation and impact of ablation: A systematic review and meta-analysis.

This systematic review and meta-analysis examined the progression of persistent atrial fibrillation (PsAF) to permanent atrial fibrillation (AF) in various populations.

Heart RhythmMay 21, 2026Read summary
Clinical ResearchCardiology

Direct His/LBB pacing as an alternative to biventricular pacing in patients with HFrEF and a typical LBBB: Design and rationale for the His-Alternative II trial.

The His-Alternative II trial is a multicenter, randomized non-inferiority study comparing conduction system pacing (CSP) to biventricular pacing (BiV-CRT) in patients with heart failure and left bundle branch block.

Am Heart JMay 20, 2026Read summary
Clinical ResearchCardiology

Superficial intercostal plane blocks for post-sternotomy pain control rationale and design for the EPOCH CardioLink-10 randomized clinical trial.

The EPOCH CardioLink-10 trial is a double-blind, placebo-controlled, multicenter randomized trial assessing the impact of continuous bilateral superficial parasternal intercostal plane (SPIP) blocks on opioid…

Curr Opin CardiolMay 20, 2026Read summary
Clinical ResearchCardiologyOpen access

Safety, tolerability, pharmacokinetics, pharmacodynamics and food effect of HRS-1893, a cardiac myosin inhibitor, in healthy subjects.

This Phase I randomized controlled trial evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of HRS-1893, a cardiac myosin inhibitor, in healthy subjects.

Br J Clin PharmacolMay 20, 2026Read summary
Clinical ResearchCardiologyOpen access

Effects of Aerobic Exercise on Heart Rate Variability and C-Reactive Protein in Middle-Aged Adults With Normal Weight and Overweight/Obesity: A Pilot Study.

This controlled clinical trial investigated the effects of a 16-week aerobic exercise program on heart rate variability (HRV) and C-reactive protein (CRP) in middle-aged adults with normal weight and overweight/obesity.

Res Nurs HealthMay 20, 2026Read summary
Case ReportOncology (Medical)

Isolated cardiac metastasis after comprehensive treatment with hepatocellular carcinoma: a case report and literature review.

A 61-year-old male with BCLC-B stage hepatocellular carcinoma (HCC) underwent liver resection and subsequent treatments, including immunotherapy and radiofrequency ablation.

Acta Chir BelgMay 20, 2026Read case
Clinical ResearchCardiology

Accelerated Diagnostic Pathways for Suspected Acute Coronary Syndrome in Practice: A Randomized Trial of 0/1-Hour vs 0/3-Hour Troponin Testing.

This pragmatic randomized trial compared the 0/1-hour and 0/3-hour high-sensitivity troponin (hs-cTn) testing pathways for suspected acute coronary syndrome (ACS) in 3,543 patients across two emergency departments.

J Am Coll CardiolMay 20, 2026Read summary
Clinical ResearchCardiology

Cost-effectiveness of catheter ablation in end-stage heart failure with atrial fibrillation: Insights from CASTLE-HTx.

The CASTLE-HTx trial evaluated the cost-effectiveness of catheter ablation combined with guideline-directed medical therapy (GDMT) versus medical therapy alone in 194 patients with end-stage heart failure and atrial…

Heart RhythmMay 19, 2026Read summary

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