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1333 articles
October 202624
Family-Centered Child Obesity Treatment: The TEAM UP Randomized Clinical Trial.
This pragmatic randomized clinical trial evaluated the effectiveness of enhanced standard of care with family-based behavioral treatment (ESOC+FBT) compared to enhanced standard of care alone (ESOC) in reducing percent…
Erythropoietin for Neonatal Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial.
This multicenter randomized clinical trial evaluated the efficacy of erythropoietin (EPO) as an adjunct to therapeutic hypothermia in infants with moderate to severe hypoxic-ischemic encephalopathy (HIE).
Bone Accrual During Puberty Suppression and Gender-Affirming Therapy in Transgender Adolescents: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated bone mineral density (BMD) and z scores in transgender adolescents undergoing gonadotropin-releasing hormone agonist (GnRHa) therapy followed by gender-affirming…
Autonomous Oxygen Titration for Maintaining Normoxemia in Acutely Ill Adults: The SAVE-O2 AI Randomized Clinical Trial.
The SAVE-O2 AI randomized clinical trial evaluated the effectiveness of autonomous oxygen titration in maintaining normoxemia in acutely ill adults receiving supplemental oxygen.
Health Communication and Stepped Reminders Interventions for Lung Cancer Screening: A Randomized Clinical Trial.
This randomized clinical trial evaluated two patient-centered interventions aimed at increasing adherence to annual lung cancer screening among patients with normal findings.
Negative affect influences the computations underlying food choice in bulimia nervosa.
This randomized controlled trial examined how negative affect influences food choice dynamics in 25 women with bulimia nervosa (BN) and 21 healthy controls.
A double-blind multi-centre randomised placebo-controlled trial of doxycycline in women with recurrent miscarriage and chronic endometritis defined by CD138 positive stromal cells.
This multicenter, double-blind, randomized controlled trial evaluated the effect of preconceptual doxycycline on live birth rates in women with recurrent miscarriage and chronic endometritis defined by CD138 positive…
Histological Analysis Shows That a Moisturizer Formulated for Dermatoporosis Increases Elastin Content and Improves Skin Elasticity.
This multicenter clinical trial evaluated the effects of a novel moisturizer (GC cream) on skin biomarkers in individuals aged 40 to 60 with dermatoporosis.
The impact of unilateral endometriomas on ovarian response to stimulation: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the impact of unoperated unilateral endometriomas on ovarian response during stimulation cycles in women with endometriosis.
Reporting Gaps in mHealth Intervention Studies for Adults With Diabetes: Systematic Review.
This systematic review evaluated the reporting completeness of 144 randomized controlled trials (RCTs) on mHealth interventions for adults with diabetes using the mERA checklist.
Irritability in the Mix: An Exploratory Study of the Role of Irritability in Characterising Mood Disorders.
This randomized controlled trial explored the relationship between irritability and mixed states in 82 patients with bipolar disorder over 18 months.
Balloon Enteroscopy-Assisted ERCP and EUS-Guided Biliary Drainage for Malignant Biliary Obstruction in Patients With Surgically Altered Anatomy: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed balloon enteroscopy-assisted ERCP (BEA-ERCP) versus EUS-guided biliary drainage (EUS-BD) for malignant biliary obstruction in patients with surgically altered anatomy.
Effect of Skin-To-Skin Contact During Caesarean Section on Pain and Stress in Newborns: A Randomized Controlled Trial.
This randomized controlled trial evaluated the impact of skin-to-skin contact during caesarean sections on neonatal pain and stress during the first intramuscular injection.
Bipolar Disorder and Perimenopause: An Update.
This systematic review examined the relationship between bipolar disorder (BD) and perimenopause, analyzing 14 studies from various countries.
Short-Term Effects of a Self-Monitoring-Based Intervention on Prolonged Sedentary Behavior in Older Adults With Cardiovascular Conditions: An Exploratory Secondary Analysis of a Randomized Controlled Trial.
This exploratory secondary analysis of a randomized controlled trial examined the impact of an accelerometer-guided self-monitoring intervention on prolonged sedentary behavior in older adults with cardiovascular…
Effect of a walnut-based low carbohydrate diet on fat redistribution and visceral fat accumulation in people with central obesity: A randomized controlled trial.
This randomized controlled trial investigated the effects of a walnut-based low carbohydrate diet (w-LCD) on fat redistribution and visceral fat accumulation in individuals with central obesity over 12 weeks.
Ultrasound-Guided Dorsal Penile Nerve Block Reduces Perioperative Opioid Requirements in Pediatric Circumcision: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness of ultrasound-guided versus landmark-based dorsal penile nerve block (DPNB) in reducing opioid requirements during pediatric circumcision.
Effects of sprint interval training on markers of metabolic health: A three-level meta-analysis of randomised controlled trials.
This systematic review and three-level meta-analysis examined randomised controlled trials comparing sprint interval training (SIT) with no-exercise control or moderate-intensity continuous training (MICT) for metabolic…
Iran's Escherichia coli AMR Landscape (2010-2025): A One Health Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined the prevalence of antimicrobial resistance (AMR) in Escherichia coli across humans, animals, foods, and the environment in Iran from 2010 to 2025.
Screening Strategies for Silent Myocardial Ischemia in Individuals With Diabetes Without Known Coronary Artery Disease: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness of routine screening for silent myocardial ischemia in asymptomatic adults with diabetes and no known coronary artery disease.
Gut microbiome and healthy ageing: a systematic review of literature.
This systematic review examined the gut microbiome's compositional and functional features associated with healthy ageing, independent of age-related diseases.
Advanced therapies for extraintestinal manifestations of IBD: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of advanced therapies (ATs) for extraintestinal manifestations (EIMs) in patients with inflammatory bowel diseases (IBD).
Opioid Use and Family Members' Experiences of Opioids in Paediatric Cancer Pain Management: An Integrative Review.
This integrative review analyzed opioid use in pediatric cancer pain management and family members' experiences. Sixteen peer-reviewed articles were reviewed, revealing that morphine and fentanyl are the most commonly…
Tumor Profile, Clinical Features, and Outcomes in Individuals With Constitutional Trisomy 8: A Systematic Review of Case Reports and Case Series.
Constitutional trisomy 8 mosaicism (CT8M) is a rare chromosomal disorder with poorly characterized cancer risk. This systematic review aimed at summarizing reported cases of malignancy and associated clinical outcomes…
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