Trending archive
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441 articles
September 202624
Brain-motor behavior coupling during walking while negotiating obstacle: A systematic review.
This systematic review examined cortical activity alongside gait during obstacle negotiation in adults, using a brain–motor behavior framework.
Alzheimer's disease and related dementias in South and Southeast Asia: a systematic review and meta-analysis of epidemiology and associated factors.
This systematic review and meta-analysis examined the prevalence and associated factors of Alzheimer's disease and related dementias (AD/ADRDs) in South and Southeast Asia, analyzing data from 31 studies.
Systematic review of cost-effectiveness analyses of weight loss interventions for knee osteoarthritis.
This systematic review assessed the cost-effectiveness of weight-loss interventions for adults with knee osteoarthritis and obesity.
Implementing the MATILDA intervention to enhance community participation for older adults with intellectual disability: A feasibility randomised controlled trial and RE-AIM guided process evaluation.
This feasibility randomized controlled trial evaluated the MATILDA intervention aimed at enhancing community participation among older adults with intellectual disabilities in the UK.
Artificial Intelligence and Machine Learning for Outcome Prediction After Osteoporotic Hip Fracture: A Systematic Review and Meta-analysis of Prediction Model Performance.
This systematic review and meta-analysis evaluated the performance of artificial intelligence (AI) and machine learning (ML) models in predicting outcomes after osteoporotic hip fractures.
Total Intravenous vs Volatile Inhalational Anesthesia for Major Noncardiac Surgery: A Randomized Clinical Trial.
This randomized clinical trial compared total intravenous anesthesia (TIVA) with volatile inhalational anesthesia in 2508 older adults (aged 50+) undergoing major noncardiac surgery.
Multifactorial and multiple component interventions for preventing falls in older people living in the community.
This systematic review and meta-analysis evaluated the effects of multifactorial and multiple component fall prevention interventions in community-dwelling older adults (≥ 60 years).
Barriers and enablers to deprescribing from the perspectives of older adults with polypharmacy and their stakeholders: A systematic review of qualitative studies.
This systematic review synthesised qualitative studies on barriers and enablers to deprescribing among older adults with polypharmacy and relevant stakeholders.
Effectiveness of Nutrition and Exercise Interventions Among Community-Dwelling Older Vietnamese Adults with Sarcopenia: A Cluster-Randomized Controlled Trial.
This cluster-randomized controlled trial evaluated the effectiveness of exercise alone and exercise with nutritional support in managing sarcopenia among 90 older Vietnamese adults aged 60-70.
Haloperidol for Hypoactive and Hyperactive Delirium in ICU Patients-A Post Hoc Bayesian Analysis of the AID-ICU Trial.
This post hoc analysis of the AID-ICU trial evaluated the effects of haloperidol on delirium subtypes in 987 ICU patients. Haloperidol was linked to more days alive out of hospital, with a 76.5% probability of greater…
"A better system" - managing the adverse effects of prescribed medicines: Cluster-randomised controlled trial and process evaluation of the ADRe Profile in primary care.
This cluster-randomized controlled trial evaluated the ADRe Profile's effectiveness in managing adverse drug reactions among patients aged ≥65 on multiple long-term medications in primary care.
Using the Social Ecological Model to identify barriers to accessing and using primary healthcare services by the rural Bangladeshi elderly: A systematic review.
This systematic review examined barriers to accessing primary healthcare services among rural elderly populations in Bangladesh, utilizing the Social Ecological Model.
Associations Between Peripheral Blood Inflammatory and Immune Markers and Osteoporotic and Fragility Fractures: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the associations between peripheral blood inflammatory and immune markers and osteoporotic or fragility fractures.
Risk factors for frailty in older adults with cancer: a systematic review.
This systematic review examined risk factors for frailty in older adults with cancer, integrating data from 30 studies. It identified six categories of influencing factors: disease-related, physiological, psychological…
Examining the Effects of Testosterone and Strength Training on Fat Mass and Functional Strength in Older Adult Males: A Systematic Review.
This systematic review evaluated the effects of testosterone therapy combined with strength training versus strength training alone in males over 60.
Impact of Dietetic Counseling Combined With Digital Tools on Obesity-Related Indices in Greek Adults: The GATEKEEPER Study.
The GATEKEEPER study evaluated the impact of dietetic counseling combined with digital tools on obesity-related outcomes in adults aged 55 and older at high risk for metabolic syndrome.
A randomised, double-blind, placebo-controlled phase I clinical trial to evaluate the safety, tolerability and immunogenicity of three doses of an adjuvanted group B Streptococcus vaccine in older adults aged 55 to 75.
This phase I randomized controlled trial assessed the safety, tolerability, and immunogenicity of an adjuvanted group B Streptococcus vaccine (GBS-AlpN) in 90 older adults aged 55 to 75, including those with obesity…
Effect of manual diaphragmatic release technique on exercise capacity and sleep quality in older adults with Type II diabetes: A randomized controlled trial.
This single-blind randomized controlled trial assessed a six-week manual diaphragmatic release (MDR) program in 44 older adults with type 2 diabetes.
Long-term SBP time in target and risk of cardiovascular events in older adults: a secondary analysis of the ASPREE cohort.
This observational study analyzed data from the ASPREE cohort of 16,730 older adults (mean age 74) to assess the relationship between systolic blood pressure (SBP) time in target range (TTR) and cardiovascular events.
Deterministic and stochastic interventions in reducing drug-drug interactions in inappropriate prescribing: A systematic review.
This systematic review evaluated interventions aimed at reducing drug-drug interactions (DDIs) in inappropriate prescribing, focusing on deterministic and stochastic models.
Analysis of postural control through nonlinear methods in older adults: a randomized controlled trial.
This randomized controlled trial investigated the impact of a six-month sensorimotor training program on postural control in 86 older adults aged 55-80.
Prediction models for sarcopenia risk in type 2 diabetes mellitus: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed multivariable models predicting sarcopenia or low muscle mass in adults with type 2 diabetes.
Approach to the patient: cases of hormonal management in older transgender and gender diverse adults.
This article presents a case-based approach to managing older transgender and gender diverse (TGD) adults undergoing gender-affirming hormone therapy.
Effect of phenylephrine versus ephedrine on the incidence of postoperative delirium in elderly patients undergoing non-cardiac and non-neurosurgical procedures: protocol for a multicentre, double-blind, randomized, controlled trial.
This multicentre, double-blind, randomized controlled trial investigates whether ephedrine is more effective than phenylephrine in reducing postoperative delirium in 1,084 elderly patients undergoing major non-cardiac…
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