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1333 articles
September 202624
TACE combined with apatinib versus TACE alone for unresectable hepatocellular carcinoma in China: a cost-effectiveness and budget impact analysis.
This study evaluated the clinical efficacy and cost-effectiveness of transarterial chemoembolisation (TACE) combined with apatinib versus TACE alone for unresectable hepatocellular carcinoma in China.
Photodynamic Diagnosis of Actinic Keratosis: A Systematic Review.
This systematic review evaluated the effectiveness of photodynamic diagnosis (PDD) for actinic keratosis (AK) across 37 studies.
Reduced oxaliplatin exposure in gastrointestinal cancers: A systematic review and meta-analysis.
This systematic review and random-effects meta-analysis compared reduced oxaliplatin exposure (ROE) with standard-duration oxaliplatin-based therapy in gastrointestinal cancers.
Candida tropicalis in environmental and animal reservoirs: a systematic review from a One Health perspective.
This systematic review examined Candida tropicalis in environmental and animal sources, synthesizing evidence on antifungal susceptibility, virulence-associated traits, and resistance mechanisms.
A Randomized Comparative Effectiveness Trial of Many-Features and Few-Features Variants of Semantic Feature Analysis Treatment for Naming Impairment in Aphasia.
This randomized comparative effectiveness trial tested whether the number of semantic features generated during semantic feature analysis (SFA) affects naming outcomes in 41 people with aphasia following left-hemisphere…
Acupuncture for chemotherapy-induced nausea and vomiting: An umbrella review of systematic reviews.
This umbrella review assessed invasive acupuncture for chemotherapy-induced nausea and vomiting (CINV), synthesizing existing systematic reviews and meta-analyses and conducting a renewed meta-analysis of primary…
Prenatal Mindfulness Training and Race-Related Vigilance: A Mixed-Methods Study Among Pregnant Women at Risk for Hypertensive Disorders.
This mixed-methods study, conducted within a randomized clinical trial, examined prenatal mindfulness training in 53 pregnant women of color at risk for hypertensive disorders.
Switching to Daily Doravirine/Islatravir (100/0.25 mg) Maintains Viral Suppression Through Week 48 Despite Baseline Non-Nucleoside Reverse Transcriptase Inhibitor Resistance-Associated Mutations or M184I/V in Proviral DNA.
This phase III clinical trial evaluated the effects of baseline resistance-associated mutations (RAMs) on the virologic response to doravirine/islatravir (DOR/ISL) in 1227 virologically suppressed adults with HIV-1.
Long-Term Psychodynamic Psychotherapy for Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the effectiveness of long-term psychodynamic psychotherapy (LTPP) for reducing depressive symptoms across 16 randomized controlled trials with 1992 participants.
Psychosocial stress and risk of first-ever stroke: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the link between psychosocial stress and the risk of first-ever stroke in a stroke-free population, analyzing 84 studies with over 4 million participants.
Randomized, placebo-controlled trial of N-acetylcysteine in Parkinson's disease patients: a pilot study.
This randomized, placebo-controlled pilot trial assessed the tolerability of oral N-acetylcysteine (NAC) 1200 mg/day in 42 Parkinson's disease patients over one year.
Effectiveness and Safety of Colorectal Cancer Screening Via Fecal Occult Blood Testing: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed the effectiveness of colorectal cancer screening via fecal occult blood tests in adults aged 45-75.
Inducible displacement measured with radiostereometric analysis in primary knee arthroplasty: a systematic review of clinical studies.
This systematic review evaluated inducible displacement measured by radiostereometric analysis (RSA) in 23 studies of primary knee arthroplasty.
Efficacy and safety of Braun enteroenterostomy in patients undergoing pancreatoduodenectomy: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of Braun enteroenterostomy (BEE) in 2731 patients undergoing pancreatoduodenectomy (PD).
Intraoperative Calcar Fractures in Uncemented Total Hip Replacement: A Systematic Review.
This systematic review analyzed 60 studies involving 465,030 primary uncemented total hip arthroplasties (THAs) to evaluate intraoperative calcar fractures (IOCFs).
Preclinical and clinical evaluation of systemic danegaptide for the treatment of nonproliferative diabetic retinopathy.
This phase 1b clinical trial evaluated the safety and early efficacy of danegaptide, an oral medication, in patients with nonproliferative diabetic retinopathy (NPDR) and mild center-involved macular edema.
The effect of lifestyle interventions in women with polyendocrine metabolic ovarian syndrome: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness of lifestyle interventions in women with polyendocrine metabolic ovarian syndrome (PMOS).
Effect of Chinese medicine compound on intestinal bifidobacteria recovery and CD4+ T-Cell activation in postoperative chemotherapy patients with breast cancer .
This randomized controlled trial investigated the effects of a traditional Chinese medicine compound on intestinal bifidobacteria recovery and CD4+ T-cell activation in breast cancer patients undergoing postoperative…
Is ultra-early endoscopy always beneficial? A systematic review and meta-analysis of timing-dependent outcomes in nonvariceal upper gastrointestinal bleeding.
This systematic review and meta-analysis evaluated the impact of ultra-early endoscopy (≤6 hours) versus early endoscopy (>6 hours) on clinical outcomes in adults with nonvariceal upper gastrointestinal bleeding…
Five-Year Follow-Up of the Phase III ASCOT Trial of Adjuvant S-1 After Resection for Biliary Tract Cancer.
This prespecified five-year follow-up of the multicenter, open-label, randomized phase III ASCOT trial assessed adjuvant S-1 versus observation after resection for biliary tract cancer in 440 patients in Japan.
Effective Dose 90 of Programmed Intermittent Epidural Bolus Volume at Three Ropivacaine Concentrations with Dural Puncture Epidural for Labor Analgesia: A Randomized Sequential Allocation Study.
This randomized controlled trial evaluated the effective dose 90 (ED90) of programmed intermittent epidural bolus (PIEB) volume for labor analgesia using three concentrations of ropivacaine (0.075%, 0.1%, 0.125%) in 90…
Intrauterine infusion of autologous platelet-rich plasma (PRP) versus granulocyte colony-stimulating factor (G-CSF) prior to single frozen blastocyst transfer in women with thin endometrium: a study protocol for a multicentre sequential multiple assignment randomised trial.
This multicentre randomized controlled trial aims to compare the effectiveness of intrauterine infusion of autologous platelet-rich plasma (PRP) versus granulocyte colony-stimulating factor (G-CSF) in women with thin…
Patient experiences with digital health interventions in self-management of rheumatic and musculoskeletal diseases: a systematic review and qualitative meta-synthesis.
This systematic review and qualitative meta-synthesis examined patient experiences with digital health interventions (DHIs) for self-management in rheumatic and musculoskeletal diseases (RMDs).
Pharmacokinetics and Dose Optimization of Ethambutol in Children on First-Line Antituberculosis Therapy: An Individual Patient Data Meta-Analysis.
This meta-analysis examined the pharmacokinetics of ethambutol (EMB) in 220 children aged 0.2-15 years undergoing first-line tuberculosis therapy.
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