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359 articles

September 202618

Clinical ResearchGeneral Surgery

Efficacy and safety of laparoscopic-guided transversus abdominis plane block versus port-site local anesthetic infiltration in laparoscopic cholecystectomy: A systematic review, meta-analysis, and trial sequential analysis.

This systematic review and meta-analysis evaluated the efficacy and safety of laparoscopic-guided transversus abdominis plane (LTAP) block versus port-site local anesthetic infiltration in 711 patients undergoing…

Medicine (Baltimore)Sep 4, 2026Read summary
Clinical ResearchAnesthesiology

Remimazolam versus sevoflurane for general anaesthesia: A meta-analysis with trial sequential analysis of haemodynamic and clinical outcomes.

This meta-analysis compared remimazolam and sevoflurane for general anaesthesia, analyzing 12 RCTs with 739 patients. Remimazolam significantly reduced intraoperative hypotension (RR 0.38, 95% CI 0.25 to 0.57; P <…

Eur J AnaesthesiolSep 4, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Efficacy of different doses of oliceridine for Patient-Controlled Intravenous Analgesia in patients undergoing Total Laparoscopic Hysterectomy.

This randomized controlled trial evaluated the efficacy and safety of three doses of oliceridine (0.1, 0.35, and 0.5 mg/kg) for patient-controlled intravenous analgesia in patients undergoing total laparoscopic…

PLoS OneSep 3, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

The effect of intravenous dexamethasone in supraclavicular brachial plexus block at Halibet National Referral Hospital, Eritrea 2024-2025: A randomized clinical trial.

This randomized clinical trial evaluated the effect of intravenous dexamethasone on postoperative analgesia in 60 patients undergoing upper limb surgery with supraclavicular brachial plexus block.

PLoS OneSep 3, 2026Read summary
Case ReportAnesthesiologyOpen access

Ultrasound-Guided Infraspinatus-Teres Minor Interfascial Block versus Interscalene Brachial Plexus Block for Analgesia After Arthroscopic Shoulder Surgery: A Randomized Non-Inferiority Clinical Trial.

This randomized non-inferiority trial was designed to verify whether ultrasound-guided infraspinatus-teres minor interfascial block (ITMB) could produce non-inferior postoperative analgesia in adult patients undergoing…

Drug Des Devel TherSep 3, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Effects of erector spinae plane block on postoperative pain in patients undergoing implant-based breast reconstruction for breast cancer: a randomized controlled trial.

This randomized controlled trial evaluated the impact of a single-shot T5 erector spinae plane block (ESPB) on postoperative pain in 100 adults undergoing implant-based breast reconstruction.

Ann MedSep 2, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Duloxetine for postoperative pain management in total hip and knee arthroplasty: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the efficacy of perioperative duloxetine for pain management in patients undergoing total hip and knee arthroplasties.

J Orthop Surg ResSep 2, 2026Read summary
Clinical ResearchCardiothoracic Surgery

Rethinking Transfusion Strategies in CABG: Acute Normovolaemic Haemodilution <em>versus</em> Conventional Transfusion: A Systematic Review.

This systematic review evaluated the effectiveness of acute normovolaemic haemodilution (ANH) compared to conventional transfusion practices in patients undergoing coronary artery bypass grafting (CABG).

J Coll Physicians Surg PakSep 1, 2026Read summary
Case ReportAnesthesiology

Awake emergency laparotomy under combined spinal epidural anaesthesia in a high-risk patient with severe pulmonary disease and neuromuscular blocking agent anaphylaxis.

A frail elderly patient with severe chronic obstructive pulmonary disease and anaphylaxis to multiple neuromuscular blocking agents underwent an awake emergency laparotomy using combined spinal-epidural anaesthesia.

BMJ Case RepSep 1, 2026Read case
Case ReportAnesthesiologyOpen access

Percutaneous Cervical Cordotomy for Refractory Cancer Pain With General Anesthesia and Neuromonitoring: A Case Report.

A 54-year-old woman with metastatic gallbladder carcinoma presented with severe unilateral abdominal pain unresponsive to standard treatments.

Pain PractSep 1, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Blood Pressure Targets During General Anaesthesia in High-Risk Patients-A Randomised Clinical Feasibility Trial.

This multicenter randomized clinical trial evaluated the feasibility of different blood pressure targets during general anaesthesia in 483 high-risk patients (ASA 3-5).

Acta Anaesthesiol ScandSep 1, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Positive End-Expiratory Pressure, Tidal Volume, and Fraction of Inspired Oxygen During General Anaesthesia in High-Risk Patients-A Randomised Clinical Feasibility Trial.

This multicenter randomized clinical trial evaluated different ventilatory settings during general anesthesia in 483 high-risk patients (ASA 3-5).

Acta Anaesthesiol ScandSep 1, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Rebound Pain and Patient Satisfaction With Dexamethasone as an Adjunct for Peripheral Nerve Blocks. A Substudy Based on Two Randomised Clinical Trials.

This substudy pooled data from two randomized controlled trials to evaluate the effect of dexamethasone on pain and rebound pain after peripheral nerve blocks in 159 patients undergoing osseous surgery.

Acta Anaesthesiol ScandSep 1, 2026Read summary
Clinical ResearchAnesthesiology

Etomidate combined with TAPB in ovarian cancer surgery: A controlled study on hemodynamics and immune response.

This randomized controlled trial evaluated the effects of etomidate combined with transversus abdominis plane block (TAPB) on hemodynamics and immune response in 80 patients undergoing ovarian cancer surgery.

Pak J Pharm SciSep 1, 2026Read summary
Clinical ResearchEmergency MedicineOpen access

Virtual reality simulation for tracheostomy emergencies: a randomized educational intervention.

This randomized controlled trial assessed the effectiveness of immersive virtual reality (VR) simulation training for managing tracheostomy emergencies among critical care fellows.

ATS SchSep 1, 2026Read summary
Clinical ResearchAnesthesiology

Analgesic Effects of Intravenous Lidocaine in Laparoscopic Surgery: A Systematic Review and Meta-Analysis With Trial Sequential Analysis.

This systematic review and meta-analysis evaluated the effects of intravenous lidocaine on postoperative pain in adults undergoing laparoscopic surgery, including 45 randomized clinical trials with 2599 patients.

Clin J PainSep 1, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

The safety and effectiveness of lumbar transforaminal injection of sterile amniotic fluid filtrate compared to steroid for lumbosacral radicular pain due to spinal stenosis: a phase I/II double-blinded randomized trial.

This phase I/II double-blinded randomized trial evaluated the safety and effectiveness of lumbar transforaminal injections of human amniotic fluid filtrate (hAF) versus dexamethasone in 58 patients with lumbosacral…

Pain MedSep 1, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Haemodynamic effects of selective venoconstriction with centhaquine in spontaneously breathing patients with mixed hypovolaemic-vasodilatory shock.

This multicenter phase IV clinical trial investigated the effects of centhaquine on hemodynamics in 15 spontaneously breathing patients with mixed hypovolaemic-vasodilatory shock.

Exp PhysiolSep 1, 2026Read summary

August 20266

Case ReportGastroenterologyOpen access

Effect of Lidocaine Spray on the Sedative Dose of Remimazolam During Gastroscopy in Adults: A Prospective, Randomized Dose-Response Trial Using an Up-Down Sequential Allocation Method.

To investigate the effect of oropharyngeal topical lidocaine spray on the sedative dose of remimazolam required for gastroscopy in adults.

Drug Des Devel TherAug 31, 2026Read case
Clinical ResearchAnesthesiologyOpen access

The effect of BIS-guided sevoflurane anesthesia on postoperative nausea and vomiting in pediatric adenoidectomy: a prospective randomized controlled trial.

This prospective randomized controlled trial evaluated the impact of BIS-guided sevoflurane anesthesia on postoperative nausea and vomiting (PONV) in 58 children aged 3-8 undergoing adenoidectomy.

Sao Paulo Med JAug 31, 2026Read summary
Case ReportGastroenterologyOpen access

An Oxycodone-Based Conscious Analgesia Strategy with Supplemental Low-Dose Propofol Improves Safety in Elderly Obese Patients Undergoing Gastroscopy: A Prospective Randomized Controlled Trial.

During diagnostic gastroscopy, intolerance is usually manifested as retching, coughing, and involuntary movement. Conscious analgesia relieves discomfort while patients continue to breathe spontaneously and remain…

Drug Des Devel TherAug 30, 2026Read case
Case ReportNeurology

Ultrasound-Guided Lumbar Puncture:Experience in Two Difficult Cases.

This report details two challenging cases of lumbar puncture in patients with spinal deformities and prior lumbar surgery. Traditional anatomical landmarks were insufficient for accurate localization, necessitating the…

Zhongguo Yi Xue Ke Xue Yuan Xue BaoAug 30, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Effect of protective ventilation throughout the intubation period on perioperative oxygenation in patients undergoing MIDCABG: a randomised controlled trial.

This randomized controlled trial evaluated the effects of protective lung ventilation (PLV) during intubation on perioperative oxygenation in 60 patients undergoing minimally invasive direct coronary artery bypass…

Ann MedAug 26, 2026Read summary
Clinical ResearchAnesthesiology

Neuromuscular blocking agents for tracheal intubation of critically ill adults: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of neuromuscular blocking agents (NMBAs) on first-attempt success rates and adverse events during emergency intubations in critically ill adults.

Eur J Emerg MedAug 24, 2026Read summary

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