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1998 articles

September 202624

Clinical ResearchOrthopedic Surgery

What to do with K-wires in displaced upper extremity fractures in children - where to bury or not.

This systematic review and meta-analysis evaluated the complication rates of buried versus exposed Kirschner wires (K-wires) in pediatric upper extremity fractures, involving 1,977 patients.

Eur J Trauma Emerg SurgSep 29, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Feasibility of deep learning reconstruction algorithm combined with the "ultra triple-low" protocol at 60 kVp in CTPA: An image quality and radiation dose assessment.

This randomised controlled trial assessed whether deep learning reconstruction could support pulmonary CT angiography using 60 kVp, 10 ml of iodine contrast, and a 2.5 ml/s injection rate.

Eur J RadiolSep 29, 2026Read summary
Clinical ResearchEmergency Medicine

The utilisation of international consensus definitions of the disease polytrauma: a systematic review.

This systematic review evaluated the uptake of the Newcastle and Berlin consensus definitions of polytrauma in studies published from 2015 to 2025.

Eur J Trauma Emerg SurgSep 29, 2026Read summary
Clinical ResearchOncology (Medical)

Unveiling the Prognostic Power of Circulating Tumor DNA in Multiple Myeloma: A Systematic Review and Updated Meta-Analysis.

This systematic review and meta-analysis evaluated the prognostic significance of circulating tumor DNA (ctDNA) in 948 patients with multiple myeloma (MM).

Cancer MedSep 29, 2026Read summary
Case ReportMedical Genetics

A Heterozygous Variant in the GABBR2 Gene in a Girl With Clinical Classic Rett Syndrome.

A girl diagnosed with classic Rett syndrome exhibited developmental stagnation, loss of purposeful hand use, stereotypic movements, autonomic dysfunction, and behavioral issues.

Mol Genet Genomic MedSep 29, 2026Read case
Case ReportEmergency Medicine

Rotational thromboelastometry guided transfusion in venom-induced consumptive coagulopathy following a haemotoxic snakebite.

A woman in her 30s presented with severe haemotoxic snake envenoming and venom-induced consumptive coagulopathy (VICC), leading to early multiorgan involvement.

BMJ Case RepSep 29, 2026Read case
Clinical ResearchOncology (Medical)Open access

Time toxicity in cancer care: a systematic review of definitions and measurement methods.

This systematic review examined the definitions and measurement methods of time toxicity in cancer care, involving 56 studies primarily from high-income countries.

Support Care CancerSep 29, 2026Read summary
Case ReportInfectious Diseases

Lumbar spinal brucellosis presenting as an atypical epidural abscess.

A man in his 50s presented with low back pain and lower limb radiculopathy. MRI revealed a ventral epidural collection at L4-L5, resembling a sequestered disc fragment, without significant vertebral or disc involvement.

BMJ Case RepSep 29, 2026Read case
Case ReportOphthalmology

Autologous retinal transplant for macular hole in retinal detachment following bag-intraocular lens complex dislocation.

An elderly patient in their late 80s presented with total retinal detachment and a macular hole following pars plana vitrectomy for a dislocated capsular bag-intraocular lens complex.

BMJ Case RepSep 29, 2026Read case
Clinical ResearchNeurologyOpen access

Efficacy of transcranial alternating current stimulation on cognitive function in patients with dementia: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the efficacy of transcranial alternating current stimulation (tACS) on cognitive function in 357 dementia patients across 9 randomized controlled trials.

Neurol SciSep 29, 2026Read summary
Clinical ResearchPsychiatry

Designing Youth Early Intervention in Psychosis Services: A Secondary Framework Synthesis of Organisational Recommendations.

This systematic review synthesized organizational recommendations from 26 international guidelines on early intervention in psychosis (EIP) for youth.

Early Interv PsychiatrySep 29, 2026Read summary
Clinical ResearchNeurology

Continuous Versus Routine EEG in Critically Ill Patients Without Primary Neurologic Condition: Analysis of a Randomized Controlled Trial.

This post hoc analysis of the multicenter randomized CERTA trial evaluated the effectiveness of continuous EEG (cEEG) versus routine EEG (rEEG) in critically ill patients without primary neurologic conditions.

Eur J NeurolSep 29, 2026Read summary
Clinical ResearchEndocrinology

Petrelintide, a human amylin analogue for the treatment of obesity (ZUPREME 1): a randomised, double-blind, placebo-controlled, phase 2 trial.

This multicentre, randomised, double-blind, placebo-controlled phase 2 trial assessed once-weekly petrelintide in adults with obesity or overweight with hypertension or dyslipidaemia, without type 2 diabetes.

Lancet Diabetes EndocrinolSep 29, 2026Read summary
Clinical ResearchEndocrinology

Sarcopenia in Indian adults with type 2 diabetes: a systematic review and meta-analysis of prevalence and associated factors.

This systematic review and meta-analysis assessed the prevalence of sarcopenia among Indian adults with type 2 diabetes mellitus (T2DM).

BMJ OpenSep 29, 2026Read summary
Clinical ResearchCardiology

The Effect of Carbetocin on Cardiac Repolarization: A Randomized, Placebo- and Positive-Controlled QT/QTc Study in Healthy Adults.

This randomized controlled trial assessed the impact of a supratherapeutic dose of carbetocin on cardiac repolarization in 42 healthy adults.

Clin Transl SciSep 29, 2026Read summary
Clinical ResearchObstetrics & Gynecology

GLP-1 receptor agonist exposure in the periconceptional period and adverse obstetric outcomes: A systematic review and meta-analysis.

This systematic review and random-effects meta-analysis examined observational studies comparing pregnancies with and without GLP-1 receptor agonist exposure during pregnancy or within six months before a positive…

MedSep 29, 2026Read summary
Case ReportPsychiatry

Recurrent serotonin syndrome during low-dose venlafaxine treatment in a patient with reduced CYP2D6 activity.

A man in his late 70s with transthyretin amyloidosis experienced recurrent serotonin syndrome while on low-dose venlafaxine treatment.

BMJ Case RepSep 29, 2026Read case
Clinical ResearchGastroenterology

Long-term clinical outcomes of stem cell-based interventions in Crohn's-related perianal fistula: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the long-term outcomes of stem cell-based interventions for Crohn's disease-related perianal fistulas in 750 patients.

Colorectal DisSep 29, 2026Read summary
Case ReportNeurologyOpen access

Stroke mimic caused by severe hypomagnesemia: a case report and literature review.

A patient with a history of transient neurological deficits presented with stroke-like symptoms, including hemiparesis and aphasia. The patient was on Proton Pump Inhibitors and Metformin.

J NeurolSep 29, 2026Read case
Clinical ResearchGeriatricsOpen access

Dual Sensory Impairment and Depressive Symptoms: Association and Pathways in Three Cohorts and a Meta-Analysis.

This meta-analysis examined the relationship between dual sensory impairment (DSI) and depressive symptoms in three aging cohorts: CHARLS, HRS, and ELSA.

Depress AnxietySep 29, 2026Read summary
Case ReportOphthalmology

The FIRE technique - A tube ligation alternative.

A patient undergoing glaucoma surgery with a nonvalved glaucoma drainage device (GDD) was treated using the Flanged Intraluminal Ripcord Element (FIRE) technique.

Indian J OphthalmolSep 29, 2026Read case
Case ReportOrthopedic Surgery

A Case Report to Explore A Wrong-Site Surgery Error.

A case of wrong-site surgery involved an incorrect nerve block performed during a nonemergent orthopedic procedure. Despite some verification steps being completed, the incident was attributed to lapses in established…

AORN JSep 29, 2026Read case
Clinical ResearchPediatrics

Effect of strengths-based, tiered, accessible resources and supports (STARS) for Kids project, a codesigned hybrid service delivery framework to identify and support child development, parent mental health and psychosocial needs among parents and carers of children aged 6 months to 3 years: a randomised controlled trial protocol.

This randomized controlled trial protocol evaluates the STARS for Kids model, designed to enhance early identification and support for child development and parental mental health among parents of children aged 6 months…

BMJ OpenSep 29, 2026Read summary
Clinical ResearchOncology (Medical)

Prophylactic Immediate Lymphatic Reconstruction for the Prevention of Secondary Lymphedema: A Systematic Review and Meta-Analysis of Comparative Studies.

This systematic review and meta-analysis evaluated the effectiveness of prophylactic lymphovenous shunting (LVS) in preventing secondary lymphedema in 2261 patients undergoing axillary and inguinal lymph node…

MicrosurgerySep 29, 2026Read summary

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