Trending archive
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406 articles
September 20266
A global overview of microsporidia infection in HIV/AIDS patients: an updated systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the prevalence and species distribution of microsporidia in HIV/AIDS patients, analyzing 39 studies from 18 countries.
Mediterranean Diet Reduces Inflammation in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the impact of the Mediterranean diet (MD) on inflammation and oxidative stress biomarkers in 3,476 adults across 33 randomized controlled trials.
Effects of Acute Low- and Moderate-Dose Alcohol on Chronic Disease-Related Biomarkers in Healthy Light and Heavy Drinkers.
This randomized controlled trial examined the effects of low-dose (0.35 g/kg) and moderate-dose (0.60 g/kg) alcohol on disease-related biomarkers in 32 healthy adults, both light and heavy drinkers.
Effect of Age and Age-Defined Menopausal Status on Linaclotide Efficacy and Safety in Adults With Irritable Bowel Syndrome With Constipation or Chronic Idiopathic Constipation: Post Hoc Analyses of Phase 2b/3 Studies.
This post hoc analysis of eight randomized, placebo-controlled trials evaluated linaclotide's efficacy and safety in adults with irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation…
Impact of evidence-based feeding protocols on clinical outcomes and nutritional delivery in critically ill adults: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of evidence-based feeding protocols on clinical outcomes and nutritional delivery in critically ill adults.
Dietary Soybean vs. Palm Oils Differ in Effects on Liver Fat in Adults With MAFLD: A 16-Week, Double-Masked, Randomized Controlled Trial.
This 16-week, double-masked randomized controlled trial compared soybean oil, rich in linoleic acid, with palm oil in adults with metabolic dysfunction-associated fatty liver disease (MAFLD).
August 202618
Proton pump inhibitors in invasively ventilated patients with SARS-CoV-2: a substudy of the re-evaluating the inhibition of stress erosions trial.
This substudy of the REVISE trial evaluated the effects of pantoprazole in 532 mechanically ventilated patients with SARS-CoV-2.
IgG4-related disease involving facial, infraorbital, auriculotemporal and optic nerves: multinervous cranial involvement in an adult patient.
A man in his mid-40s presented with rapidly progressive orbital symptoms initially diagnosed as orbital cellulitis. Despite treatment, his condition deteriorated, leading to multiple cranial nerve involvement.
Natriuretic Peptide and Transthyretin and Their Relationship With Clinical Outcomes: Results From ATTRIBUTE-CM, a Randomized Controlled Trial.
This post hoc biomarker analysis of ATTRIBUTE-CM, a phase 3 randomized, double-blind, placebo-controlled trial, examined baseline NT-proBNP and serum transthyretin (sTTR) in 632 participants with transthyretin amyloid…
Comparative Effectiveness of Chlorthalidone Versus Hydrochlorothiazide and Dose-Response of Amiloride on Blood Pressure and Biochemical Parameters.
This 12-week factorial randomized clinical trial compared chlorthalidone 25 mg with hydrochlorothiazide 50 mg, and amiloride 5 mg with 10 mg, assessing office and ambulatory blood pressure and laboratory parameters.
Acute water ingestion influences lean soft tissue estimation from dual-energy x-ray absorptiometry: Implications for clinical diagnosis.
This randomized controlled trial investigated the effects of acute water ingestion (AWI) on dual-energy X-ray absorptiometry (DXA) estimates of lean soft tissue (LST) in 46 participants.
Anticoagulation for Atrial Fibrillation with Intermediate Stroke Risk.
This multicenter randomized controlled trial evaluated the efficacy of direct oral anticoagulant (DOAC) therapy in patients with atrial fibrillation at intermediate stroke risk in South Korea.
Acetazolamide mitigates opioid-associated sleep-disordered breathing.
This randomized controlled trial investigated the effects of oral acetazolamide on sleep-disordered breathing (SDB) in nine adults with opioid-associated SDB.
Traditional, complementary, and integrative medicine therapies for mild/moderate acute COVID-19: a systematic review and network meta-analysis.
This systematic review and network meta-analysis evaluated the effectiveness of Traditional, Complementary, and Integrative Medicine (TCIM) therapies for mild/moderate acute COVID-19 in 18,627 patients across 69 trials.
Kratom-Associated Pulmonary Toxicity: A Systematic Review of Case Reports and Forensic Series with a Proposed Clinical Phenotype Classification.
Kratom use has increased, including concentrated 7-hydroxymitragynine products, but pulmonary toxicity has not been systematically synthesized.
Effect of diet macronutrient content on the cardiometabolic response to weight loss: A randomized clinical trial.
This randomized clinical trial examined the impact of different macronutrient compositions in diets on cardiometabolic responses to moderate weight loss in individuals with metabolically unhealthy obesity.
Effectiveness of Antiseptic and Antibiotic Use to Prevent Central Line-Associated Bloodstream Infections in ICU Patients: A Systematic Review and Narrative Synthesis of Randomized Clinical Trials.
This systematic review evaluated the effectiveness of antiseptics and antibiotics in preventing central line-associated bloodstream infections (CLABSI) in ICU patients.
Butyrylcholinesterase Activity as a Mortality Marker in ICU Patients: An Individual Participant Data Meta-Analysis.
This meta-analysis evaluated the prognostic value of butyrylcholinesterase (BChE) activity for in-hospital mortality in critically ill adults, primarily those with sepsis.
Effect of Peer Comparison Feedback and Professional Norms on Vitamin D Testing and Generic Medication Prescribing.
This randomized controlled trial evaluated the impact of peer comparison feedback on vitamin D testing and generic medication prescribing among primary care physicians in Switzerland.
Cardiorespiratory and Metabolic Responses After Sleeve Gastrectomy in Adults With Obesity: Systematic Review.
This systematic review examined cardiorespiratory and metabolic responses after sleeve gastrectomy in adults with obesity. It included seven observational reports involving 162 participants from two independent cohorts…
Assessment of the safety and efficacy of sodium pentaborate pentahydrate in individuals with overweight and obesity: a randomized, double-blind, placebo-controlled, phase 1/2 dose-finding trial.
This randomized, double-blind, placebo-controlled phase 1/2 trial evaluated the safety and preliminary efficacy of sodium pentaborate pentahydrate in 177 adults with overweight or obesity over 12 weeks.
Protein requirements and determinants of protein catabolic rate in critically ill patients with acute kidney injury: A post hoc analysis of the ENGINE randomized controlled trial.
This post hoc analysis of the ENGINE randomized controlled trial evaluated protein requirements in 78 critically ill patients with acute kidney injury (AKI).
Quadriceps muscle behavior assessed by ultrasound in septic patients: A systematic review.
This systematic review examined the use of ultrasound to assess quadriceps muscle atrophy in adults with sepsis or septic shock in ICUs.
Association between seminal and serum iron parameters and male infertility: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the relationship between iron levels and male infertility, analyzing data from ten studies with 985 participants.
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