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782 articles
September 202624
Clinical development of human vaccine candidates against Shigella flexneri: a systematic review of clinical trials.
This systematic review evaluated the clinical evidence for human vaccine candidates against Shigella flexneri, focusing on safety, immunogenicity, and efficacy.
Multiple hepatic artery pseudoaneurysms associated with visceral larva migrans: a rare cause of upper gastrointestinal bleeding in a child.
A 3-year-old girl presented with prolonged fever, abdominal pain, and haematemesis. Laboratory tests revealed anaemia, elevated eosinophils, jaundice, high serum IgE, and positive Toxocara serology.
Recurrent breast abscess leading to an incidental diagnosis of tuberculous mastitis: a case report.
A 26-year-old Indian woman presented with a recurrent right breast abscess characterized by a tender, fluctuant swelling. Initial management included incision and drainage.
PCR-Confirmed Convexity Subarachnoid Neurocysticercosis with Negative Serology: A Case Report.
A patient with a six-month history of focal seizures was diagnosed with convexity subarachnoid neurocysticercosis after surgical excision of a cystic lesion.
Molecular based diagnostic testing for urinary tract infections: the results remain unclear.
This systematic review evaluated the impact of molecular-based diagnostic testing for urinary tract infections (UTIs) in adults, focusing on studies published from January 2023 to October 2025.
Encephalitic rabies following cat bites: two cases in northern Uganda.
Two Ugandan males presented with rapidly progressive encephalitic rabies following cat bites. Both cases exhibited typical clinical features of rabies, leading to a swift decline in neurological function and ultimately…
Campylobacter jejuni as a Rare Pathogen in CIED Pocket Infections: A Case Report and Literature Review.
An immunocompromised patient developed a pacemaker pocket infection caused by Campylobacter jejuni following dual-chamber pacemaker implantation.
Malakoplakia mimicking a colonic tumour: imaging findings, non-surgical management and follow up.
A woman in her 60s with diabetes presented with a mass lesion in the descending colon, which was initially suspected to be malignant based on imaging findings.
Disseminated Fusarium infection following cladribine chemotherapy for hairy-cell leukaemia.
A young, healthy patient developed an angioinvasive Fusarium infection following cladribine chemotherapy for hairy cell leukaemia.
A 16-Year-Old Male Patient With Severe Electrical Burns With Chronic and Recurrent Hospital-Acquired Opportunistic Infection With Carbapenem-Resistant Acinetobacter baumannii.
A 16-year-old male presented with severe electrical burns and was admitted to the ICU with impaired consciousness and recurrent fever. His condition was complicated by respiratory failure and gastrointestinal bleeding.
Coinfection of Pneumocystis jirovecii and Aspergillus fumigatus in the lung: A case report.
A 66-year-old male with mantle cell lymphoma and a history of corticosteroid therapy presented with worsening pulmonary symptoms.
Infective endocarditis presenting with myocardial infarction with non-obstructive coronary arteries: A case report and literature review.
A 52-year-old male on long-term hemodialysis presented with acute chest pain, shortness of breath, and sweating. Initial ECG showed ST-segment depression, and elevated troponin I levels indicated myocardial infarction.
Helcococcus kunzii as a rare etiological agent of spondylodiscitis partially managed with oral antibiotic therapy in a patient with diabetes mellitus: a case report.
A 62-year-old man with type 1 diabetes mellitus presented with severe lumbar pain, leading to a diagnosis of spondylodiscitis confirmed by MRI.
Fatal Cutaneous Mucormycosis Initially Misdiagnosed as Necrotizing Fasciitis in an Uncontrolled Diabetic Patient: A Case Report Highlighting Diagnostic Delay.
A 64-year-old male with undiagnosed diabetes presented with altered consciousness and extensive necrotic lesions, initially diagnosed as bacterial necrotizing fasciitis.
A randomised, double-blind, placebo-controlled phase I clinical trial to evaluate the safety, tolerability and immunogenicity of three doses of an adjuvanted group B Streptococcus vaccine in older adults aged 55 to 75.
This phase I randomized controlled trial assessed the safety, tolerability, and immunogenicity of an adjuvanted group B Streptococcus vaccine (GBS-AlpN) in 90 older adults aged 55 to 75, including those with obesity…
Empirical Antibiotic Therapy for the Management of Empyema Thoracis in Children: A Systematic Review.
This systematic review evaluated empirical antibiotic therapy for empyema thoracis in children, analyzing 17 studies from various databases.
AI-Based Sepsis Prediction in Hospitalized Adults: Systematic Review, Subgroup Meta-Analysis, and Contextual Analysis of Clinical Burden.
This systematic review and meta-analysis evaluated machine learning (ML) and deep learning (DL) models for sepsis prediction in hospitalized adults, analyzing 34 studies.
A systematic review of ultrasound to predict severe disease in patients with dengue and other viral infections associated with hemorrhagic fevers.
This systematic review and meta-analysis evaluated ultrasound findings in patients with viral infections associated with hemorrhagic fevers (VaHFs) to predict severe disease.
Immunogenicity and safety of high-dose versus standard-dose quadrivalent inactivated influenza vaccine in patients living with HIV: a randomized controlled trial.
This randomized controlled trial evaluated the immunogenicity and safety of high-dose (HD) versus standard-dose (SD) quadrivalent inactivated influenza vaccine in patients living with HIV.
Switch to injectable cabotegravir-rilpivirine given every 8 weeks in adolescents living with HIV with virological suppression in sub-Saharan Africa (LATA): a randomised, open-label, multicentre, 96-week non-inferiority trial.
LATA was a randomised, open-label, multicentre, 96-week non-inferiority trial comparing injections of cabotegravir-rilpivirine every 8 weeks with daily oral dolutegravir-lamivudine-tenofovir disoproxil fumarate in…
Factors affecting hand hygiene adherence among critical care healthcare workers: A systematic review.
This PRISMA-guided systematic review examined factors associated with hand hygiene adherence among healthcare workers in intensive care units and emergency departments.
Cryptococcal meningitis with cerebrospinal fluid human immunodeficiency virus escape presenting as transient diplopia and areflexia.
A man in his early 40s with stable HIV on antiretroviral therapy presented with transient binocular diplopia and areflexia.
Clinical Perspective on Exophiala dermatitidis, A Systematic Review of Cases Reported Globally over 36 Years.
This systematic review analyzed 77 reported cases of Exophiala dermatitidis infections from 1989 to 2024, highlighting a rise in cases, particularly since 2010.
Late Diagnosis of Noonan Syndrome Presenting With Infective Endocarditis: A Multidisciplinary Challenge in an Underserved Population.
A 29-year-old woman from a rural area presented with severe respiratory distress, weight loss, and new cardiac murmurs. Examination revealed dysmorphic features indicative of Noonan syndrome.
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