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1999 articles
September 202624
Evaluating the Impact of CYP1A2 Inhibition on the Pharmacokinetics of Savolitinib: A Phase 1 Open-Label Study.
This Phase 1 open-label study assessed the effects of CYP1A2 inhibition by fluvoxamine on the pharmacokinetics of savolitinib in 16 healthy male volunteers.
Opposite seasonal variation in nighttime and morning blood pressure: a longitudinal study of patients with hypertension.
This longitudinal study examined seasonal variations in nighttime and morning blood pressure (BP) among 419 hypertensive patients using home blood pressure monitoring.
AdvanTIG-105: a phase I/Ib dose-expansion study of ociperlimab plus tislelizumab with or without chemotherapy in metastatic non-small cell lung cancer and extensive-stage small cell lung cancer.
The AdvanTIG-105 study evaluated the combination of ociperlimab and tislelizumab, with or without chemotherapy, in patients with metastatic non-small cell lung cancer (NSCLC) and extensive-stage small cell lung cancer…
Fabella Syndrome Following Arthroscopic Lateral Meniscectomy with Serial Imaging Findings: A Case Report.
A 54-year-old woman experienced persistent posterolateral knee pain one year after undergoing arthroscopic lateral meniscectomy.
Immune Checkpoint Inhibition in Locally Advanced Periocular Squamous Cell Carcinoma (POLA-SCC).
A 75-year-old man presented with recurrent upper eyelid squamous cell carcinoma (SCC) that persisted despite multiple surgical excisions and reconstructive efforts, leading to significant eyelid dysfunction and visual…
Surveillance of antibiotic-resistant bacteria integrating whole genome sequencing and epidemiological information - a global, systematic review, 2012-2023.
This systematic review examined global surveillance systems for antibiotic-resistant bacteria (ARB) integrating whole genome sequencing (WGS) and epidemiological data.
Lacrimal Gland Choristoma and Associated Ocular Anomalies: A Review and Description of a Bilateral Gland Choristoma With Unique Features.
A young female presented with bilateral epibulbar lacrimal gland choristoma, which was associated with a limbal dermoid and ocular colobomatous anomalies.
Associations Between Gut Microbiota and Immune Profiles in Community-Dwelling Older Adults and the Regulatory Role of Polygonatum odoratum.
This randomized controlled trial investigated the effects of Polygonatum odoratum on gut microbiota and immune profiles in 140 community-dwelling older adults aged 60 and above over 90 days.
Renal synovial sarcoma occurring synchronously with renal cell carcinoma.
A patient in his 50s presented with abdominal pain and hematuria, leading to the discovery of a primary biphasic synovial sarcoma of the kidney alongside synchronous clear cell renal cell carcinoma.
A novel approach to treating Endometriosis-Related Repeated IVF failures- insights from single case report.
A young nulligravida with peritoneal endometriosis experienced recurrent implantation failure and poor embryo quality during multiple IVF attempts.
Pharmacological treatment of sleep disorder phenotypes in Parkinson's disease: a systematic review and meta-analysis of randomised controlled trials.
This systematic review and meta-analysis evaluated the efficacy and safety of pharmacological treatments for sleep disorders in Parkinson's disease, analyzing 29 randomized controlled trials with 1913 participants.
Prognostic Value of the C-Reactive Protein-Albumin-Lymphocyte Index in Hepatobiliary and Pancreatic Cancers: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the prognostic value of the C-reactive protein-albumin-lymphocyte (CALLY) index in patients with hepatobiliary and pancreatic cancers.
Dietary fibre blend improves gut health in patients with irritable bowel syndrome following a low FODMAP diet: a randomised, double-blind control trial.
This randomized, double-blind controlled trial investigated the effects of a 3-week ur gut ® supplementation on gut health in 26 adults with irritable bowel syndrome (IBS) following a low FODMAP diet.
A rare ATM variant in a Colombian family with chorea-ataxia syndrome: implications for an early diagnosis.
A 39-year-old man presented with progressive ataxia, chorea, and telangiectasias, alongside two siblings with similar symptoms. Genetic testing revealed compound heterozygous variants in the ATM gene.
Utilization of human amniotic membrane (HAM) in tympanoplasty: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the use of human amniotic membrane (HAM) as a graft material in tympanoplasty, analyzing data from eight studies involving 265 tympanoplasties.
Prenatal allostatic load and adverse pregnancy outcomes: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the relationship between prenatal allostatic load (AL) and adverse pregnancy outcomes (APOs) in a population of 8,795 pregnant women.
A parathyroid adenoma masquerading as an oesophageal cyst.
A male in his 60s presented with ventricular fibrillation arrest, severe hypercalcaemia, and elevated parathyroid hormone levels, leading to a suspicion of primary hyperparathyroidism.
When immunotherapy mimics pancreatic cancer: mass-forming immune-related pancreatitis during neoadjuvant treatment for triple-negative breast cancer.
A woman with early triple-negative breast cancer developed four hypermetabolic pancreatic lesions after 4 months of neoadjuvant chemoimmunotherapy, initially suggestive of metastases.
Surgical management of gallbladder volvulus.
An elderly female in her 80s presented with abdominal pain and vomiting after experiencing intermittent colicky pain for three days. Examination revealed tenderness over a palpable gallbladder.
Giant choledochal cyst - type VI B.
A man in his early 20s presented with jaundice, abdominal pain, and right upper quadrant fullness. Imaging revealed a type VI B choledochal cyst, characterized by significant dilatation of the cystic duct and common…
Immune Thrombotic Thrombocytopenic Purpura: Diagnosis and Management.
A middle-aged patient with a history of immune-mediated thrombotic thrombocytopenic purpura (iTTP) presented with a relapse characterized by thrombocytopenia and microangiopathic hemolytic anemia.
Classic mantle cell lymphoma with aberrant immunohistochemical expression of Fc receptor-like 4/immunoglobulin superfamily receptor translocation-associated 1.
A patient diagnosed with classic mantle cell lymphoma (MCL) presented with typical clinical, morphologic, immunophenotypic, and genetic features.
Primary Orbital Melanoma: A Systematic Review of Clinical Characteristics, Management and Outcomes.
This systematic review evaluated clinical characteristics, management, and outcomes of 112 patients with histopathologically confirmed primary orbital melanoma (POM).
Anaphylaxis to both pegfilgrastim and sargramostim in a patient with diffuse large B-cell lymphoma.
A woman in her early 60s with stage 3A diffuse large B-cell lymphoma experienced anaphylaxis to pegfilgrastim after her first cycle of R-CHOP chemotherapy, presenting with syncope and severe hypotension.
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