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441 articles

August 202610

Clinical ResearchGeriatrics

Response-optimised training improves learning of a complex motor task and closely related motor tasks.

This randomized controlled trial investigated the effects of response-optimized dynamic balance training on motor learning in 30 healthy older adults.

Exp GerontolAug 6, 2026Read summary
Clinical ResearchInternal Medicine (General)

An expanded breakfast buffet increases daily energy and protein intakes in hospitalised patients: A prospective crossover quality improvement study.

This randomized controlled trial evaluated the impact of an expanded breakfast buffet on daily energy and protein intakes in hospitalized patients.

Clin NutrAug 6, 2026Read summary
Clinical ResearchNeurologyOpen access

Blue light therapy delivered through light glasses improves sleep quality and daytime sleepiness in Parkinson's disease: A randomized trial.

This randomized controlled trial evaluated the effects of blue light therapy delivered through glasses on sleep quality and daytime sleepiness in individuals with Parkinson's disease.

J Parkinsons DisAug 6, 2026Read summary
Clinical ResearchGeriatrics

Nutritional Support With Or Without Exercise for Older Adults With GLIM-Compatible Malnutrition: A Meta-Analysis of Randomized Controlled Trials.

This meta-analysis evaluated the impact of adding exercise to nutritional support in older adults with GLIM-compatible malnutrition.

Clin TherAug 5, 2026Read summary
Clinical ResearchGeriatrics

Responsiveness of muscle mass gain to different load intensities of resistance training in older women: A randomized crossover study.

This randomized crossover study examined the effects of two resistance training load intensities (15RM and 10RM) on skeletal muscle mass (SMM) in 27 older women.

Exp GerontolAug 4, 2026Read summary
Clinical ResearchGeriatrics

Effects of digital health-based exercise interventions on older adults with sarcopenia: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis evaluated the efficacy of digital health-based exercise interventions for older adults with sarcopenia, including 14 randomized controlled trials with 927 participants.

Exp GerontolAug 4, 2026Read summary
Clinical ResearchGeriatrics

Who Responds Positively? Examining Factors Associated With Benefits From Exposure to the Individualized Positive Psychosocial Interaction (IPPI) Program.

This pragmatic clinical trial evaluated the Individualized Positive Psychosocial Interaction (IPPI) program in 130 nursing home residents with dementia.

J Am Med Dir AssocAug 4, 2026Read summary
Case ReportInfectious Diseases

Case Commentary: Emergence of clinically relevant fidaxomicin-resistant Clostridioides difficile strains.

An elderly patient with Clostridioides difficile infection (CDI) experienced treatment failure while on a pulsed-taper fidaxomicin regimen.

Antimicrob Agents ChemotherAug 3, 2026Read case
Clinical ResearchEndocrinology

Intensive glycemic control in adults aged 80 years and older: A randomized trial evaluating diabetes complications and competing mortality.

This randomized controlled trial evaluated the effects of intensive glycemic control on diabetes complications in adults aged 80 years and older.

Diabetes Res Clin PractAug 3, 2026Read summary
Clinical ResearchGeriatrics

Optimal aerobic exercise dose for improving metabolic health and functional outcomes in frail older adults: A systematic review and dose-response meta-analysis.

This systematic review and dose-response meta-analysis evaluated the effects of aerobic exercise on frailty and health outcomes in adults aged 60 and older.

Clin NutrAug 1, 2026Read summary

July 202614

Clinical ResearchGeriatrics

Effectiveness of an Augmented Reality-Assisted Baduanjin on Multidimensional Frailty Among Older Adults in Long-Term Care Facility: A Three-Arm Randomized Controlled Trial.

This three-arm randomized controlled trial assessed the impact of augmented reality (AR)-assisted Baduanjin on multidimensional frailty in 117 older adults (average age 75.5 years) in long-term care facilities.

J Am Med Dir AssocJul 31, 2026Read summary
Clinical ResearchGeriatrics

Early mobilization within 24 to 48 h improves postoperative clinical outcomes in older adults with hip fracture: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effects of early mobilization (within 24 to 48 hours) on postoperative outcomes in older adults with hip fractures.

Int J Nurs StudJul 31, 2026Read summary
Clinical ResearchGeriatrics

A systematic review of the current prognostic tools used to predict the survival length of people living with advanced dementia.

This systematic review evaluated prognostic tools for estimating survival in individuals with advanced dementia, analyzing data from 225,553 patients across various settings.

Palliat MedJul 31, 2026Read summary
Clinical ResearchNeurology

Effects of Exergame Balance Training with Variable Cognitive Motor Challenges on Serum BDNF, p-tau181, and Cognitive Functions in Adults with Mild Cognitive Impairment: A Randomized Trial.

This randomized controlled trial investigated the effects of cognitive-motor exergame balance training on serum BDNF, p-tau181, and cognitive functions in 97 adults with mild cognitive impairment (MCI).

Games Health JJul 30, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Beyond Glycaemia: Fear of Hypoglycaemia, Cognition and Functional Mobility After Advanced Hybrid Closed-Loop Therapy in Older Adults With Type 1 Diabetes: A Prespecified Secondary Analysis of a Randomised, Single-Centre Study.

This randomized controlled trial evaluated the effects of advanced hybrid closed-loop (AHCL) therapy on psychological and functional outcomes in older adults (≥65 years) with type 1 diabetes.

Diabetes Obes MetabJul 30, 2026Read summary
Clinical ResearchNeurology

Changes in hippocampal functional connectivity and volume associated with cognitive improvement and decline in amnestic mild cognitive impairment following computerized cognitive training.

This randomized controlled trial investigated hippocampal changes associated with cognitive improvement in 50 individuals with amnestic mild cognitive impairment (aMCI) following computerized cognitive training (CCT).

J Psychiatr ResJul 30, 2026Read summary
Clinical ResearchPediatrics

Evaluating a culturally adapted question prompt list to improve end-of-life communication among indonesian migrant caregivers: A randomized controlled trial with qualitative insights.

This randomized controlled trial evaluated a culturally adapted Question Prompt List (QPL) aimed at improving end-of-life communication among 60 Indonesian caregivers in Taiwan.

Patient Educ CounsJul 29, 2026Read summary
Clinical ResearchGeriatricsOpen access

Interventions for Oral Frailty and Related Oral Functional Decline in Older Adults: A Systematic Review.

This systematic review evaluated non-pharmacological interventions for oral frailty in older adults aged 65 and above, analyzing 23 studies with 2,412 participants.

J Oral RehabilJul 29, 2026Read summary
Clinical ResearchGeriatricsOpen access

Epigenetic aging biomarkers in dietary geroscience: feasibility, participant perceptions, and trial design considerations.

This randomized controlled trial assessed the feasibility of using epigenetic aging biomarkers in dietary interventions among 34 adults aged 48-81 with metabolic syndrome.

GeroscienceJul 29, 2026Read summary
Clinical ResearchGeriatrics

The prevalence and impact of medication-related harm in people living with dementia - a systematic review and meta-analysis.

This systematic review and meta-analysis examined the prevalence and impact of medication-related harm in people living with dementia (PLWD).

Res Social Adm PharmJul 29, 2026Read summary
Clinical ResearchGeriatricsOpen access

Effect of probiotics on humoral responses to COVID-19 vaccination in older adults: a randomized, placebo-controlled trial (PIRATES-COV study).

This randomized controlled trial evaluated the effect of probiotics on immune responses to COVID-19 vaccination in older adults (ages 65-89) in Quebec, Canada.

Gut MicrobesJul 28, 2026Read summary
Clinical ResearchInternal Medicine (General)

Assessment and CommuniCation ExcelLEnce foR sAfe paTient outcomEs (ACCELERATE): A stepped-wedge cluster randomised trial evaluating the effectiveness of a nurse-led assessment and handover communication intervention on patient adverse events.

The ACCELERATE trial, a stepped-wedge cluster randomised trial conducted over 12 months in three metropolitan hospitals, evaluated a nurse-led assessment and communication intervention aimed at reducing patient adverse…

Int J Nurs StudJul 28, 2026Read summary
Clinical ResearchGeriatrics

Mediterranean diet adherence modulates the plasma antioxidant response to long-term extra-virgin olive oil consumption in older adults.

This randomized controlled trial evaluated the impact of long-term consumption of extra-virgin olive oil (EVOO) on plasma total antioxidant capacity (TEAC) in 34 older adults at high cardiovascular risk.

Clin Nutr ESPENJul 28, 2026Read summary
Clinical ResearchGeriatrics

A self-determination theory-based cognitive prosthetic to improve medication adherence in African American older adults with diabetes.

This randomized controlled trial evaluated the efficacy of MediTeddi, a cognitive prosthetic, in improving medication adherence among African American older adults with poorly controlled type 2 diabetes.

Exp GerontolJul 27, 2026Read summary

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