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2000 articles
October 202624
Efficacy and Safety of Lorundrostat for Uncontrolled and Treatment-resistant Hypertension: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the efficacy and safety of lorundrostat in adults with uncontrolled or treatment-resistant hypertension.
How I do it: meningioangiomatosis of the sylvian fissure. The need for a tailored functional neurosurgery.
A patient with drug-resistant epileptic seizures presented with meningioangiomatosis located in the right sylvian fissure, affecting the M1-M2 segments of the right middle cerebral artery.
Lenalidomide-Related Diarrhea in Patients with Multiple Myeloma Is Associated with Gut Microbiota Dysbiosis and Disruption of the Bile Acid Pool.
This Phase II randomized controlled trial investigated the relationship between gut microbiota dysbiosis, bile acid pool disruption, and lenalidomide-related diarrhea (LRD) in patients with multiple myeloma.
A Composite Ovine Forestomach Matrix and Hyaluronic Acid CAMP for the Treatment of Full Thickness Wounds of the Foot in People With Diabetes: A Randomized Controlled Trial.
This randomized controlled trial evaluated the efficacy of a novel composite CAMP, OFM-HA, in treating full thickness diabetic foot ulcers (DFUs) in 143 patients.
Diagnostic Accuracy of Circulating MicroRNAs for Coronary Artery Disease: An Updated Systematic Review and Meta-analysis.
This systematic review and meta-analysis evaluated the diagnostic accuracy of circulating microRNAs (miRNAs) for coronary artery disease (CAD) in 3,879 participants across 24 studies.
Association of HRD Score With Efficacy of Neoadjuvant Short-Course Radiotherapy Plus Sequential Chemoimmunotherapy in pMMR Locally Advanced Rectal Cancer.
This Phase II clinical trial examined the relationship between homologous recombination deficiency (HRD) score and treatment response in 32 patients with mismatch repair-proficient locally advanced rectal cancer…
A systematic review and meta-analysis of preoperative MRI-based pelvimetry in predicting surgical difficulty in rectal cancer: Implications for personalised surgical planning.
This systematic review and meta-analysis evaluated the role of MRI-based pelvimetry in predicting surgical difficulty during total mesorectal excision (TME) for rectal cancer, involving 8,364 patients across 36 studies.
Psychoeducation for Youth at Clinical High-Risk of Psychosis.
This clinical trial evaluated the effects of psychoeducation on 54 youth at clinical high risk of psychosis. After 2-6 months, significant improvements were noted in attenuated psychotic symptoms, depression, and…
Sensory processing and executive functioning interaction in neurodevelopmental disorders and at-risk conditions: A systematic review and meta-analysis.
This systematic review and meta-analysis examined associations between sensory processing (SP) and executive functioning (EF) in children and adolescents aged 0–18 with neurodevelopmental disorders or at-risk…
Hair Follicle-Derived Grafting for Chronic Cutaneous Wounds: A Systematic Review of Clinical Outcomes.
This systematic review evaluated the clinical outcomes of hair follicle-derived grafting techniques for chronic cutaneous wounds, analyzing 16 studies with 239 patients.
Efficacy and Safety of Traditional Chinese Medicine in Treating Chronic Obstructive Pulmonary Disease with Osteoporosis: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of traditional Chinese medicine (TCM) as an adjunct to conventional treatment for chronic obstructive pulmonary disease (COPD) with osteoporosis…
Temporal Patterns of Outcomes After DMARD Tapering or Withdrawal in Rheumatoid Arthritis With Sustained Disease Control: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effects of DMARD tapering and withdrawal in patients with rheumatoid arthritis (RA) who had sustained disease control.
Effectiveness of a Sodium Intake Monitoring Smartphone Application (NamakBan) on Clinical Outcomes of Patients Diagnosed With Hypertension: A Randomized Clinical Trial.
This randomized clinical trial evaluated the effectiveness of the NamakBan smartphone application for monitoring sodium intake in 88 adults with primary hypertension.
A 12-week randomized controlled trial of the dietary approaches to stop hypertension (DASH) diet in seropositive rheumatoid arthritis: Effects on disease activity and outcomes.
This 12-week parallel-group randomized controlled trial evaluated a DASH diet intervention versus usual diet in 82 patients with seropositive rheumatoid arthritis. Forty-nine participants completed the study.
Evaluating plasma ferritin and suPAR as treatable traits for critically ill patients with COVID-19 treated with anakinra: an exploratory analysis of the immune modulation domain of the REMAP-CAP randomised clinical trial.
This exploratory analysis of the REMAP-CAP randomized clinical trial evaluated plasma ferritin and suPAR as potential treatable traits for anakinra in critically ill COVID-19 patients.
A Novel FAM111A Frameshift Variant Associated With Osteoclast Necroptosis and KCS2-like Syndrome.
Kenny-Caffey syndrome type II (KCS2) is a rare genetic disorder characterized by skeletal abnormalities, impaired growth, and developmental delay.
NIHSS and Large Artery Atherosclerosis Affect Efficacy of Dual Antiplatelet Therapy Versus Alteplase for Minor Stroke.
This randomized controlled trial analyzed the efficacy of dual antiplatelet therapy (DAPT) versus alteplase in patients with minor stroke (NIHSS 0-5) and assessed the impact of large artery atherosclerosis (LAA).
Factors influencing access to green health prescribing in primary care for older adults - a qualitative systematic review.
This systematic review examined barriers and enablers to green health prescribing (GHP) for older adults with long-term conditions.
Efficacy of US-guided Hydrodissection for Carpal Tunnel Syndrome: A Prospective Randomized Controlled Trial.
This prospective randomized controlled trial evaluated the efficacy of three US-guided hydrodissection techniques for treating carpal tunnel syndrome (CTS) in adults with refractory symptoms.
Use of a Synthetic Polylactic Acid Matrix for Pyoderma Gangrenosum: A Case Series.
This case series involved six patients with chronic, non-healing ulcers due to pyoderma gangrenosum, persisting for 6 months to 3 years.
Effects of Estriol-Lactobacilli Combination Versus Polycarbophil-Based Vaginal Moisturizer on Post-Radiation Vaginitis in Women With Cervical Cancer: A Randomized Controlled Trial.
This randomized controlled trial evaluated the efficacy of an estriol-lactobacilli combination vaginal tablet (E3/L) versus a polycarbophil-based vaginal moisturizer (PBVM) in 34 women with post-radiation vaginitis…
Portable Dynamometry Is Reliable for Measuring Knee and Ankle Strength in Daily Practice: Results From a Systematic Review With Meta-analysis and Evidence Gap Map Using the COSMIN Methodology.
This systematic review and meta-analysis evaluated the reliability and criterion validity of portable dynamometers for measuring knee and ankle muscle strength in both uninjured individuals and those with lower-limb…
Factors affecting the experience of procedural and postoperative pain in children and adolescents - a systematic review.
This systematic review examined factors influencing procedural and postoperative pain in children and adolescents aged 3-18 years.
Quercetin in Myocardial Ischemia-Reperfusion Injury: Mechanistic Evidence, Cardioprotective Effects, and Translational Challenges.
This systematic review assessed the cardioprotective effects of quercetin in myocardial ischemia-reperfusion (I/R) injury, primarily in preclinical studies.
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