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2000 articles

September 202624

Case ReportVascular Surgery

Power Doppler ultrasonography for positional graft compression after femoral artery reconstruction: A case report.

A 35-year-old male presented with pain and numbness during deep knee flexion, 3.5 years post-femoral artery reconstruction using the great saphenous vein.

Medicine (Baltimore)Sep 25, 2026Read case
Clinical ResearchPediatrics

The Use of Waivers of Guardian Permission in the United States for Pediatric Digital Health Intervention Research Since 2020: Systematic Review.

This systematic review examined the use of guardian permission waivers in pediatric digital health intervention research in the U.S. from 2020 to 2026.

J Med Internet ResSep 25, 2026Read summary
Case ReportOrthopedic Surgery

Giant subpatellar synovial osteochondromatosis complicated by osteoarthritis of the knee: A case report.

A 71-year-old woman presented with a 2-year history of progressive pain and swelling in her left knee, leading to significant movement restriction and impairment in daily activities.

Medicine (Baltimore)Sep 25, 2026Read case
Case ReportCardiothoracic Surgery

Cervical aortic arch with severe left ventricular dysfunction in a neonate: successful repair using whole-body perfusion.

A neonate presented with a right cervical aortic arch, coarctation, and significantly reduced left ventricular function. Surgical intervention involved arch repair with aortic uncrossing, utilizing whole-body perfusion…

Multimed Man Cardiothorac SurgSep 25, 2026Read case
Clinical ResearchNeurology

Effects of exercise interventions on gait, motor function, and balance in patients with Parkinson's disease: A meta-analysis with clinical implications.

This meta-analysis evaluated the effects of exercise interventions on gait, motor function, and balance in 714 patients with Parkinson's disease.

PLoS OneSep 25, 2026Read summary
Clinical ResearchMedical Genetics

The Psychosocial Impact of Receiving Whole Genome and Whole Exome Sequencing Results in Adults: A Systematic Review.

This systematic review assessed the psychosocial impact of whole genome sequencing (WGS) and whole exome sequencing (WES) results in adults, analyzing 45 studies.

J Genet CounsSep 25, 2026Read summary
Clinical ResearchOncology (Medical)

Progression-free survival and objective response rate as a surrogate end point for overall survival in metastatic renal cell carcinoma: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the validity of progression-free survival (PFS) and objective response rate (ORR) as surrogate endpoints for overall survival (OS) in randomized controlled trials of…

CancerSep 25, 2026Read summary
Clinical ResearchEndocrinology

Western versus Asian utilization of molecular testing for indeterminate thyroid nodules: A meta-analysis of divergent clinical impact.

This meta-analysis examined the use of molecular testing (MT) for indeterminate thyroid nodules in Western and Asian populations.

Cancer CytopatholSep 25, 2026Read summary
Clinical ResearchOncology (Medical)

Sarcopenia Is Associated With Severe Treatment Toxicity and Mortality in Older Adults With Advanced Cancer: A Secondary Analysis.

This secondary analysis of a randomized controlled trial examined the impact of sarcopenia on treatment outcomes in 161 older adults (≥ 70 years) with advanced cancer.

J Cachexia Sarcopenia MuscleSep 25, 2026Read summary
Clinical ResearchAnesthesiology

Bispectral index during remimazolam versus propofol sedation at matched depths: a randomized, double-blind crossover trial in healthy volunteers.

This randomized, double-blind crossover trial evaluated the bispectral index (BIS) during remimazolam versus propofol sedation in 16 healthy volunteers.

Ann MedSep 25, 2026Read summary
Clinical ResearchAllergy & Immunology

Asthma Intervention with Residential Ventilation and Air Cleaner (AIRVAC) Study: A 4-arm parallel-group randomized controlled trial protocol.

The AIRVAC study is a 4-arm parallel-group randomized controlled trial evaluating the long-term effectiveness of energy recovery ventilators and portable air cleaners in improving asthma outcomes among children and…

PLoS OneSep 25, 2026Read summary
Clinical ResearchAnesthesiology

The effect of alveolar recruitment maneuver on intraoperative hemodynamics: A randomized controlled trial.

This randomized controlled trial evaluated the impact of alveolar recruitment maneuver (RM) on intraoperative hemodynamics in 70 patients undergoing laparoscopic hysterectomy.

Medicine (Baltimore)Sep 25, 2026Read summary
Clinical ResearchPsychiatry

Multimorbidity and the risk of depression: a systematic review of cohort studies.

This systematic review evaluated the longitudinal association between multimorbidity and the risk of developing depression, analyzing 17 cohort studies.

J Glob HealthSep 25, 2026Read summary
Clinical ResearchPediatrics

Can we do better in identifying child developmental conditions early? Sensitivity and specificity of the Watch Me Grow Integrated (WMG-I) digital developmental screening and surveillance tool in Australia.

This randomized controlled trial evaluated the diagnostic accuracy of the 'Watch Me Grow Integrated' (WMG-I) digital developmental screening tool in 16-to-35-month-old children in Australia.

BMJ OpenSep 25, 2026Read summary
Clinical ResearchAnesthesiology

Effectiveness and safety of ultrasound-guided quadratus lumborum block combined with low-dose spinal anesthesia versus general anesthesia in percutaneous nephrolithotomy: a randomized controlled trial.

This randomized controlled trial evaluated the effectiveness and safety of ultrasound-guided quadratus lumborum block (QLB) combined with low-dose spinal anesthesia (LDSA) versus general anesthesia (GA) in 70 adults…

Arch Ital Urol AndrolSep 25, 2026Read summary
Clinical ResearchPulmonology

Accuracy of Artificial Intelligence in Diagnosing Obstructive Sleep Apnea Using Photoplethysmography: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the diagnostic accuracy of AI-based methods using photoplethysmography (PPG) for obstructive sleep apnea (OSA) in adults.

J Med Internet ResSep 25, 2026Read summary
Clinical ResearchEndocrinology

Network meta-analysis of intrathyroidal injection of combined dexamethasone with lidocaine for subacute thyroiditis.

This meta-analysis evaluated the efficacy of intrathyroidal dexamethasone (Dex) versus oral prednisone and compared combination therapy of Dex with lidocaine to monotherapy in treating subacute thyroiditis (SAT).

Medicine (Baltimore)Sep 25, 2026Read summary
Case ReportGeneral Surgery

Migration of an ingested orthodontic retainer into the psoas muscle presenting with radiculopathy-like symptoms: A case report.

A 26-year-old man presented with abdominal pain after swallowing an orthodontic retainer. Although his abdominal pain improved, he later experienced persistent right lower-limb paresthesia and pain.

Medicine (Baltimore)Sep 25, 2026Read case
Clinical ResearchOncology (Medical)Open access

Fasting-induced metabolic reprogramming as a therapeutic vulnerability in cancer: a systematic mechanistic review of in vitro evidence.

This systematic review evaluated in vitro studies on fasting and fasting-mimicking interventions in cancer cell models. It found that fasting consistently reduced IGF-1 signaling and inhibited key metabolic pathways…

Med OncolSep 25, 2026Read summary
Clinical ResearchGeriatrics

Nonlinear dose-response of mind-body exercise in older adults with mild cognitive impairment: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the dose-response relationship of mind-body exercise on cognitive function in older adults with mild cognitive impairment (MCI).

PLoS OneSep 25, 2026Read summary
Clinical ResearchPediatrics

Turning distress into distraction: using virtual reality during penicillin injections for rheumatic fever.

This phase IIA clinical trial evaluated the use of immersive virtual reality (VR) during subcutaneous penicillin injections in 10 participants aged 9-20 years with acute rheumatic fever.

N Z Med JSep 25, 2026Read summary
Clinical ResearchOncology (Medical)

Intratumoral and Peritumoral Features for Predicting Microvascular Invasion in Hepatocellular Carcinoma: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed the effectiveness of radiomics-based models in predicting microvascular invasion (MVI) in hepatocellular carcinoma (HCC).

J Vis ExpSep 25, 2026Read summary
Case ReportNeurology

Child Neurology: Transient Global Amnesia Precipitated by a Valsalva Maneuver in an Adolescent.

A 16-year-old boy with no prior health issues experienced acute anterograde amnesia following a Valsalva maneuver during a school video.

NeurologySep 25, 2026Read case
Clinical ResearchEmergency Medicine

Intraosseous versus intravenous access in adult out-of-hospital cardiac arrest: a Bayesian secondary analysis of the PARAMEDIC-3 randomised controlled trial.

This pre-planned Bayesian secondary analysis of the PARAMEDIC-3 randomised controlled trial compared intraosseous-first with intravenous-first vascular access in adults with out-of-hospital cardiac arrest requiring…

ResuscitationSep 25, 2026Read summary

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