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441 articles

July 202624

Clinical ResearchGeriatrics

Immersive virtual reality cognitive training in older adults with mild cognitive impairment: Feasibility results from a randomized controlled trial.

This single-centre randomized controlled feasibility trial evaluated a 6-week immersive virtual reality (VR) cognitive training program in adults aged 65 years or older with mild cognitive impairment, compared with…

J Psychosom ResJul 27, 2026Read summary
Clinical ResearchGeriatrics

Age-related differences in motor unit behaviours and maximal strength: A systematic review and meta-analysis.

This systematic review and meta-analysis examined age-related differences in motor unit behaviors and their impact on maximal strength in older versus younger adults.

Neurobiol AgingJul 25, 2026Read summary
Clinical ResearchGeriatrics

Changes in the oral microbiota among dentate, edentate, and complete denture-wearing older adults: A systematic review and meta-analysis.

This systematic review and meta-analysis examined the oral microbiota differences among dentate, edentate, and complete denture-wearing older adults (≥65 years).

J DentJul 24, 2026Read summary
Clinical ResearchNeurology

Association between pulse pressure and markers of cognitive function: a systematic review and meta-analysis.

This systematic review and meta-analysis examined the relationship between pulse pressure (PP) and cognitive function across 43 studies.

J HypertensJul 24, 2026Read summary
Clinical ResearchGeriatrics

Muscle mechanical and architectural adaptations in response to different endurance training modalities in older adults.

This randomized controlled trial investigated the effects of different cycling endurance training modalities on muscle mechanical and architectural characteristics in 50 older adults (ages 59-79).

Exp GerontolJul 24, 2026Read summary
Clinical ResearchOrthopedic Surgery

Artificial intelligence in the evaluation and treatment of osteoporotic and fragility fractures: A systematic review.

This PRISMA-compliant systematic review examined original studies of artificial intelligence, machine learning, and deep learning for evaluating and managing osteoporotic and fragility fractures in adults.

InjuryJul 24, 2026Read summary
Clinical ResearchGeriatrics

Beyond multidimensionality: a systematic review of recurrent frailty archetypes in community-dwelling older adults.

This systematic review examined recurrent frailty archetypes in community-dwelling older adults by analyzing 14 reports from 12 datasets across eight countries.

Arch Gerontol GeriatrJul 23, 2026Read summary
Clinical ResearchInternal Medicine (General)

Effects of nutritional therapy on morphofunctional outcomes in critically ill patients: A systematic narrative synthesis.

This systematic review examined the effects of nutritional therapy on morphofunctional outcomes in critically ill adult ICU patients.

Clin Nutr ESPENJul 23, 2026Read summary
Clinical ResearchNeurologyOpen access

Interstitial fluid rejuvenation through young-donor plasma exchange in cognitively impaired patients: a pilot safety and feasibility study.

This pilot safety and feasibility study evaluated the effects of young-donor plasma exchange in 12 cognitively impaired patients with mild cognitive impairment and Alzheimer's disease biomarkers.

GeroscienceJul 23, 2026Read summary
Clinical ResearchGeriatrics

Effects of free-weight resistance training based on hexagonal barbell deadlift in older women: A 24-week randomized controlled trial.

This randomized controlled trial evaluated the impact of a 24-week hexagonal barbell deadlift (HBDL) resistance training program on body composition and functional performance in 32 older women (average age 67.6 years).

Exp GerontolJul 22, 2026Read summary
Clinical ResearchGeriatrics

Comparing the effects of different exercises on falls in older adults: A network meta-analysis of randomized controlled trials.

This network meta-analysis evaluated the effectiveness of various exercise interventions on fall-related outcomes in 16,240 older adults.

Int J Nurs StudJul 22, 2026Read summary
Clinical ResearchNeurologyOpen access

Dyadic Capability in Stroke Survivors and Their Caregivers: A Systematic Review and Integrated Concept Analysis.

This systematic review and integrated concept analysis examined capability and related constructs in stroke survivors and their caregivers, with the aim of clarifying capability at the dyad level.

J Cardiovasc NursJul 22, 2026Read summary
Clinical ResearchInternal Medicine (General)

Herb-drug interactions with clinical impact: A systematic review of global clinical evidence on medicinal plants widely used in Ecuador.

This systematic review analyzed clinical evidence on herb-drug interactions involving medicinal plants commonly used in Ecuador.

J EthnopharmacolJul 21, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Comparative efficacy of percutaneous vertebroplasty combined with minimally invasive pedicle screw fixation versus percutaneous vertebroplasty alone in the treatment of elderly osteoporotic vertebral compression fractures.

This randomized controlled trial evaluated the efficacy of percutaneous vertebroplasty (PVP) combined with minimally invasive pedicle screw fixation versus PVP alone in 94 elderly patients with osteoporotic vertebral…

Libyan J MedJul 21, 2026Read summary
Clinical ResearchGeriatrics

Comparative effects of 12-week resistance training on unstable and stable surfaces on muscle stiffness, muscle co-activation, and balance in older patients with knee osteoarthritis.

This randomized controlled trial evaluated the effects of unstable resistance training (URT) versus stable resistance training (SRT) on muscle stiffness, co-activation, and balance in older adults with knee…

Gait PostureJul 21, 2026Read summary
Clinical ResearchAnesthesiology

Effects of permissive hypercapnia on intraoperative cerebral oxygenation and early postoperative cognitive function in older patients with fragile brain function during the non-acute phase undergoing laparoscopic colorectal surgery: A randomized controlled trial.

This randomized controlled trial investigated the effects of permissive hypercapnia (PHC) on cerebral oxygenation and cognitive function in 76 older patients with fragile brain function undergoing laparoscopic…

Exp GerontolJul 21, 2026Read summary
Clinical ResearchInternal Medicine (General)

The effect of foot positioning on tissue oxygenation in diabetic foot ulcers.

This randomized controlled trial assessed the impact of foot positioning on tissue oxygenation in 60 hospitalized patients with diabetic foot ulcers.

Diabetes Res Clin PractJul 21, 2026Read summary
Clinical ResearchCardiology

Global, regional, and national prevalence of peripheral arterial disease in 2023: an updated systematic review and modelling study.

This systematic review and modelling study estimated the global prevalence of peripheral arterial disease (PAD) in 2023, analyzing data from over 9.7 million participants across 37 countries.

Lancet Glob HealthJul 21, 2026Read summary
Clinical ResearchGeriatrics

A Systematic Review and Meta-Analysis of Combined Cognitive and Physical Interventions on Cognition Function in Frail Older Adults.

This systematic review and meta-analysis evaluated the effectiveness of combined cognitive and physical interventions on cognitive function, frailty, gait speed, and depression in frail older adults.

J Am Med Dir AssocJul 21, 2026Read summary
Clinical ResearchGeriatrics

Clinical effectiveness of a digitally delivered balance program for older adults: a nonrandomized controlled trial.

This nonrandomized controlled trial evaluated the effectiveness of a digitally delivered balance program in older adults at risk for falls.

J Comp Eff ResJul 21, 2026Read summary
Clinical ResearchInternal Medicine (General)

Incidence and risk factors of refeeding syndrome in critically ill patients: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the incidence and risk factors of refeeding syndrome (RFS) in critically ill patients, analyzing data from 49 studies with 24,778 participants.

Clin NutrJul 21, 2026Read summary
Clinical ResearchGeriatrics

Artificial intelligence enabled social robotic interventions (PARO) in Australian dementia care: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of PARO-based socially assistive robotic interventions in reducing behavioral and psychological symptoms in dementia patients within Australian…

Int J Med InformJul 20, 2026Read summary
Clinical ResearchGeriatrics

Association between salivary oxytocin concentration and social loneliness in older adults: Findings from an uncontrolled pre-post multimodal intervention study.

This uncontrolled pre-post multimodal intervention study examined the relationship between salivary oxytocin levels and social loneliness in 62 older adults (average age 60+) in Spain.

PsychoneuroendocrinologyJul 20, 2026Read summary
Case ReportGeriatrics

Impact of a nursing intervention on frailty in people aged 65-75 years in primary care. A pilot clinical trial.

To analyse whether an intervention carried out by primary care nurses modifies the degree of frailty in people between 65 and 75 years of age.

Enferm Clin (Engl Ed)Jul 20, 2026Read case

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