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782 articles

August 202624

Clinical ResearchInfectious Diseases

Effectiveness of Antiseptic and Antibiotic Use to Prevent Central Line-Associated Bloodstream Infections in ICU Patients: A Systematic Review and Narrative Synthesis of Randomized Clinical Trials.

This systematic review evaluated the effectiveness of antiseptics and antibiotics in preventing central line-associated bloodstream infections (CLABSI) in ICU patients.

J Infus NursAug 25, 2026Read summary
Clinical ResearchInternal Medicine (General)Open access

Butyrylcholinesterase Activity as a Mortality Marker in ICU Patients: An Individual Participant Data Meta-Analysis.

This meta-analysis evaluated the prognostic value of butyrylcholinesterase (BChE) activity for in-hospital mortality in critically ill adults, primarily those with sepsis.

Crit Care ExplorAug 25, 2026Read summary
Case ReportInfectious Diseases

Genetic diversity of clinical Mycobacterium bovis BCG isolates from an immunocompromised patient with BCG infection.

The Bacillus Calmette-Guérin (BCG) vaccine is widely administered to prevent severe tuberculosis but can cause serious adverse events, including disseminated BCGosis, in immunocompromised individuals.

Infect Genet EvolAug 25, 2026Read case
Case ReportInfectious Diseases

Favorable clinical and microbiological outcomes of a war-associated prosthetic joint infection caused by Klebsiella pneumoniae treated with combined phage-colistin therapy.

A patient with a prosthetic elbow infection due to multidrug-resistant Klebsiella pneumoniae, following a war-related injury, presented after failing multiple antibiotic treatments.

Int J Infect DisAug 25, 2026Read case
Case ReportGeneral SurgeryOpen access

The Brief Case: Acute Gangrenous Appendicitis with Incidental Schistosoma Eggs in a Malian Migrant.

A 28-year-old migrant from Mali presented with 24 hours of right lower abdominal pain, anorexia, and low-grade fever. Examination, inflammatory markers, and ultrasound supported acute appendicitis.

Am J Trop Med HygAug 25, 2026Read case
Case ReportDermatologyOpen access

From Suppurative Inflammation to Fibrotic Remodeling in Cutaneous Nocardiopsis Infection.

A 77-year-old woman with hypertension and diabetes presented with ulcerated purplish-red nodules on her lower extremities, present for 3 months. Biopsy showed infectious granulomas composed predominantly of neutrophils.

Am J Trop Med HygAug 25, 2026Read case
Clinical ResearchHematologyOpen access

Fecal filtrate transplantation as salvage therapy for fulminant Clostridioides difficile infection in adult hematological patients during chemotherapy-induced aplasia: a pilot experience.

Fulminant Clostridioides difficile infection (CDI) in patients with hematologic malignancies during chemotherapy-induced aplasia carries high mortality and limited treatment options.

Gut MicrobesAug 24, 2026Read summary
Clinical ResearchInfectious Diseases

Global antibiotic consumption patterns through the lens of the WHO AWaRe framework: An umbrella review.

This umbrella review assessed global antibiotic consumption patterns through the WHO AWaRe framework, analyzing data from 20 systematic reviews and meta-analyses.

J Infect Public HealthAug 24, 2026Read summary
Case ReportNephrology

Adjunctive Varicella-Zoster Virus-Specific Immunoglobulin for Complicated Varicella-Zoster Virus Infection in Kidney Transplant Recipients: Case Series.

Three kidney transplant recipients presented with severe varicella-zoster virus (VZV) infections, including disseminated primary infection and herpes zoster with ocular involvement.

Transplant ProcAug 24, 2026Read case
Clinical ResearchPsychiatry

"Since I got the education, I feel like a kind of warrior": a qualitative study of participant perspectives and preferences about Sauti ya Vijana, a mental health intervention for young people with HIV in Tanzania.

This qualitative study explored how young people with HIV in Tanzania experienced Sauti ya Vijana (SYV), a co-created, peer-led group mental health intervention, and what they preferred about it.

AIDS CareAug 24, 2026Read summary
Case ReportOphthalmology

A Case of Adult-onset Presumed Congenital Syphilitic Keratitis: A Multidisciplinary Management Approach.

A 28-year-old man had an 11-year history of progressive bilateral redness, tearing, and visual decline. Examination showed bilateral interstitial keratitis; treponemal serology was positive and nontreponemal serology…

Eye Contact LensAug 24, 2026Read case
Clinical ResearchPediatrics

Systematic review of the mutations in the active antigenic site Ø of the prefusion F protein of the Respiratory Syncytial Virus (RSV) following the implementation of monoclonal antibody prophylaxis.

This systematic review analyzed mutations in the antigenic site Ø of the RSV prefusion F protein following the introduction of the monoclonal antibody nirsevimab in children with confirmed RSV infections.

VaccineAug 22, 2026Read summary
Clinical ResearchInfectious Diseases

LIMIT Trial: Lidocaine With Intramuscular Injection of Benzathine Penicillin G for Treponema pallidum Treatment.

The LIMIT trial was a double-blinded, randomized, placebo-controlled study comparing 0.5 mL of 1% lidocaine with 0.5 mL saline added to intramuscular benzathine penicillin G in adults treated for syphilis at one…

Sex Transm DisAug 22, 2026Read summary
Clinical ResearchPathology (Anatomic & Clinical)

Diagnostic performance of panfungal PCR on tissue specimens for the diagnosis of invasive fungal diseases: a systematic review and meta-analysis of the Fungal PCR Initiative (FPCRI).

This systematic review and meta-analysis evaluated the diagnostic performance of panfungal PCR on tissue specimens for invasive fungal diseases.

J Clin MicrobiolAug 21, 2026Read summary
Clinical ResearchOncology (Medical)

Factors impacting protective immunity conferred by vaccination with adeno-associated virus-like particles displaying human papillomavirus L2 residues 17-36.

This phase I clinical trial evaluated the immunogenicity of 20 µg AAV2-like particles displaying HPV L2 residues in 20 healthy subjects.

J VirolAug 21, 2026Read summary
Clinical ResearchInfectious Diseases

Risk of post-acute symptoms and conditions after SARS-CoV-2 compared with other respiratory viral infections: a systematic review and meta-analysis.

This systematic review and meta-analysis compared persistent symptoms and conditions in adults after SARS-CoV-2 infection with those following other acute respiratory viral infections.

Int J Infect DisAug 21, 2026Read summary
Clinical ResearchInfectious Diseases

Pathways of onward HIV disclosure in relationships among young people living with vertically acquired HIV receiving antiretroviral therapy: A qualitative analysis from the BREATHER Plus trial, South Africa.

This qualitative analysis from the BREATHER Plus trial explored how young people living with vertically acquired HIV in KwaZulu-Natal, South Africa, manage onward disclosure in relationships.

Glob Public HealthAug 20, 2026Read summary
Clinical ResearchInfectious Diseases

MIC-based tuberculosis drug susceptibility testing using Sensititre MYCOTB: a diagnostic accuracy meta-analysis.

This meta-analysis evaluated the diagnostic performance of Sensititre MYCOTB for drug susceptibility testing in multidrug-resistant (MDR) and pre-extensively drug-resistant tuberculosis (pre-XDR TB).

J Clin MicrobiolAug 20, 2026Read summary
Clinical ResearchMedical Genetics

Beyond One Gene: a systematic review of layered evidence for antileishmanial resistance in Leishmania infantum.

This systematic review examined genetic evidence for antileishmanial resistance in Leishmania infantum, focusing on 29 studies.

Infect Genet EvolAug 20, 2026Read summary
Clinical ResearchInfectious Diseases

Global prevalence of tigecycline-resistant foodborne Enterobacterales along the food chain: A meta-analysis.

This meta-analysis evaluated the global prevalence of tigecycline-resistant Enterobacterales in food and food-producing animals, analyzing 104 studies. The overall resistance rate was found to be 4.36%, with E.

Food Res IntAug 19, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Pharmacokinetics and Tolerability of Fexinidazole in Subjects with Hepatic Impairment.

This Phase I multicenter trial evaluated the pharmacokinetics of fexinidazole in 21 participants with mild and moderate hepatic impairment (HI) compared to healthy controls.

Clin Drug InvestigAug 19, 2026Read summary
Case ReportInfectious Diseases

Disseminated sporotrichosis masquerading as tuberculosis in a patient without overt immunodeficiency: challenges in tuberculosis-endemic area.

A 78-year-old man presented with progressive ulcerative skin lesions, pulmonary symptoms, and osteomyelitis over six months.

Int J Infect DisAug 19, 2026Read case
Case ReportOncology (Medical)

Cutibacterium avidum caused a liver abscess after transarterial chemoembolization for hepatocellular carcinoma.

An 83-year-old man developed a liver abscess following transarterial chemoembolization for recurrent hepatocellular carcinoma, presenting with fever 10 days post-procedure.

J Infect ChemotherAug 18, 2026Read case
Case ReportInfectious Diseases

Domiciliary colonization by Panstrongylus geniculatus associated with human blood meal in Salto do Itararé, Paraná State, Brazil.

Despite the control of Triatoma infestans in Brazil, other vectors remain implicated in the transmission of Chagas disease, making the maintenance of municipal entomological surveillance and health education actions…

Acta TropAug 18, 2026Read case

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