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196 articles
September 202624
Septic arthritis mimic unmasked: inflammatory bowel disease-associated arthritis in a patient with a learning disability.
A man in his early 30s with a mild learning disability presented with acute left-knee pain, swelling, erythema, and fevers, alongside low-back and hip pain.
Associations Between Peripheral Blood Inflammatory and Immune Markers and Osteoporotic and Fragility Fractures: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the associations between peripheral blood inflammatory and immune markers and osteoporotic or fragility fractures.
High potency and water dispersible Boswellia extract reduces pain and inflammation in subjects with osteoarthritis of the knee: A randomized, double-blind, placebo-controlled trial.
This randomized, double-blind, placebo-controlled trial evaluated the effects of a high potency Boswellia extract (OLNP-27) on knee osteoarthritis in 60 subjects aged 40 to 75.
Takayasu Arteritis in a 15-Year-Old Male Presenting with Constitutional Symptoms and Upper Limb Pulse Deficit: A Case Report a Resource-Limited Settings.
A 15-year-old male presented with several months of low-grade fever, fatigue, and joint pain, culminating in chest pain, vomiting, and significant weight loss.
Thyroid-joint crosstalk: a systematic review and meta-analysis of thyroid autoimmunity and dysfunction in juvenile idiopathic arthritis.
This systematic review and meta-analysis examined the prevalence of thyroid autoantibody positivity and dysfunction in 19,015 children with juvenile idiopathic arthritis (JIA).
Efficacy and safety of rozanolixizumab in severe fibromyalgia: a phase 2A randomised, double-blind, placebo-controlled, multicentre trial.
This phase 2A, multicentre, randomised, double-blind, placebo-controlled trial assessed rozanolixizumab in adults with severe fibromyalgia at seven sites in north west England.
Low-dose interleukin-2 for the treatment of systemic lupus erythematosus: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed clinical efficacy and safety of low-dose interleukin-2 (IL-2) in patients with systemic lupus erythematosus (SLE).
Risk of stroke in SLE: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the risk of stroke in patients with systemic lupus erythematosus (SLE) using data from 25 cohort studies involving 5,220,837 individuals.
Biologic Switching Strategies for Anti-Tumor Necrosis Factor Alpha Refractory Noninfectious Uveitis: Systematic Review and Meta-Analysis of Clinical Approach.
This systematic review and meta-analysis assessed biologic switching in patients with noninfectious uveitis refractory to anti-TNFα therapy.
Efficacy and Safety of Celecoxib Combined With Jintiange Capsules for the Treatment of Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
This randomized, double-blind, placebo-controlled trial assessed the efficacy and safety of celecoxib combined with Jintiange capsules in 120 patients with knee osteoarthritis (KOA).
Kikuchi-Fujimoto Disease Associated with Hashimoto's Thyroiditis: A Case Report.
A 37-year-old woman with a history of Hashimoto's thyroiditis presented with rapidly enlarging cervical lymphadenopathy. Laboratory tests indicated mild anemia and elevated ESR, while ultrasound revealed multiple…
Unraveling the Clinical Spectrum of DNASE1L3 Deficiency: Insights from Case Series and Systematic Literature Review.
This case series examined four children with genetically confirmed biallelic DNASE1L3 variants, revealing a diverse clinical spectrum of immune-mediated diseases.
Multidisciplinary management of an older adult with vascular Ehlers-Danlos syndrome and multiple autoimmune comorbidities.
An early 60s female with vascular Ehlers-Danlos syndrome (vEDS) presented with extensive comorbidities, including systemic lupus erythematosus and rheumatoid arthritis.
Tofacitinib reduces KL-6 levels in patients with rheumatoid arthritis-associated interstitial lung disease. Results of a phase II investigator-initiated study.
This phase II investigator-initiated clinical trial evaluated safety and outcomes with tofacitinib 5 mg twice daily in patients with rheumatoid arthritis-associated interstitial lung disease over 48 weeks.
Effects of exercise on muscle strength and characteristics in rheumatic diseases and sarcopenia: Protocol for the Care for Muscle (C4M) Study.
The C4M Study is a randomized controlled trial investigating the effects of strength versus endurance exercise on muscle strength and characteristics in patients with rheumatoid arthritis (RA), osteoarthritis (OA), and…
Global prevalence and associated factors of metabolic syndrome in patients with systemic lupus erythematosus: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed the global prevalence of metabolic syndrome (MetS) in patients with systemic lupus erythematosus (SLE).
Safety profiles of CAR-T cell therapy in systematic autoimmune diseases: a systematic review and analysis.
This systematic review analyzed the safety profiles of CAR-T cell therapy in 115 patients with autoimmune diseases. The study found that severe adverse events were rare, with cytokine release syndrome (CRS) occurring in…
The utility of 18F-fluorodeoxyglucose PET/computed tomography in relapsing polychondritis: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the utility of 18F-fluorodeoxyglucose PET/CT in relapsing polychondritis, analyzing data from three studies involving 97 patients.
Allogeneic CD19 CAR-NK cell therapy for a patient with relapsed and refractory lupus nephritis.
A patient with severe relapsed and refractory lupus nephritis, unresponsive to standard treatments, received allogeneic CD19 CAR-NK cell therapy following lymphodepleting chemotherapy.
Clinical and immunological characterization of a child with a homozygous TBK1 kinase-domain truncation.
TBK1 is a serine-tyrosine kinase protein that transmits signals from pattern recognition receptors to the NF-κB pathway leading to production of Type 1 Interferons.
Systemic sclerosis presenting as recurrent pericardial effusion despite repeatedly negative multiplex antinuclear antibody results.
A woman in her 70s presented multiple times with recurrent pericardial effusions, despite negative multiplex antinuclear antibody (ANA) results.
Severe aplastic anemia as a rare autoimmune complication of ankylosing spondylitis: A rare case report.
A 42-year-old male with a history of ankylosing spondylitis presented with recurrent mucocutaneous bleeding, severe fatigue, and transfusion dependence.
Severe vaso-occlusive lupus retinopathy: Purtscher-like retinopathy: a case report.
A 24-year-old female with systemic lupus erythematosus (SLE) developed blurred vision following COVID-19 infection, later presenting with fever, lymphadenopathy, seizures, and altered consciousness.
Diagnostic Performance of Machine Learning for Systemic Lupus Erythematosus: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the diagnostic performance of machine learning (ML) and deep learning (DL) models for systemic lupus erythematosus (SLE) classification, lupus nephritis (LN) diagnosis…
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