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1891 articles
May 202624
Memantine for Prevention of Cognitive Late Effects in Children and Adolescents Receiving Radiation Therapy for Brain Tumors: A Randomized, Controlled, Pilot Trial.
This randomized, double-blind, placebo-controlled pilot trial assessed the feasibility, acceptability, and preliminary efficacy of memantine for preventing cognitive late effects in children and adolescents receiving…
Step-by-Step Pancreaticoduodenectomy in Complete Situs Inversus: Technical Strategy to Preserve Oncologic Principles in a Rare Anatomical Setting.
A 68-year-old woman with BRCA1-mutated breast cancer and complete situs inversus presented with general deterioration and symptoms of high intestinal obstruction.
Superficial Ewing Sarcoma of the Rectum: A Case Report and the Utility of Molecular Diagnostics.
A 38-year-old male presented with rectal bleeding and was found to have an ulcerated polyp near the dentate line. An excisional biopsy revealed a monotonous round cell malignancy with necrosis and high mitotic activity.
68 Ga-PSMA Scintigraphy of Cervicothoracic Ganglioneuroma.
A 67-year-old man with newly diagnosed prostate adenocarcinoma underwent 68 Ga-PSMA PET/CT for staging, revealing a solitary PSMA-avid lesion at the thoracic inlet.
Integrating Shared Decision-Making Into Breast Cancer Postmastectomy Reconstruction: A Systematic Review of Evidence, Barriers, and Real-World Implementation.
This systematic review evaluated the effectiveness of decision aids (DAs) for postmastectomy breast reconstruction (PMBR) in enhancing shared decision-making (SDM).
Mixed Large Cell Neuroendocrine Carcinoma and Adenocarcinoma of the Cervix: A Rare Entity.
A patient presented with a rare mixed tumor of the cervix, comprising large cell neuroendocrine carcinoma and adenocarcinoma. Molecular analysis revealed the presence of HPV18 DNA in both tumor components.
A Rare Case Report of Renal Hilar Teratoma Associated With a Well-Differentiated Neuroendocrine Tumor and High-Grade Upper Urinary Tract Urothelial Carcinoma.
A 70-year-old man presented with a renal hilar mature teratoma, which contained a well-differentiated neuroendocrine tumor alongside a high-grade upper urinary tract urothelial carcinoma.
Congenital Rapidly Progressive Perianal Embryonal Rhabdomyosarcoma With Spindle Cell Morphology: A Rare Presentation.
A 2-day-old male infant presented with a painless perianal swelling that progressively enlarged over two months. MRI revealed a 4.7 × 2.7 × 2.5 cm heterogeneous mass in the perineum extending into the pelvis.
Invasive Micropapillary Carcinoma of the Breast with an Encapsulated-Like Pattern: An Unreported Entity?
A 71-year-old woman presented with a palpable left breast mass. MRI identified a 10 cm enhancing oval mass, and core needle biopsy confirmed invasive carcinoma with micropapillary features.
Penpulimab and Gemcitabine With or Without Anlotinib in Metastatic Nasopharyngeal Carcinoma: A Randomized, Open-Label, Multicenter Phase 2 Study.
This phase 2 randomized trial evaluated the efficacy and safety of anlotinib versus cisplatin in combination with gemcitabine and penpulimab for metastatic nasopharyngeal carcinoma (NPC) patients previously treated with…
Postoperative antibiotics do not reduce surgical site infections after clean thyroid and breast surgery: A randomised controlled trial from a resource-constrained setting.
This randomized controlled trial evaluated the impact of postoperative antibiotics on surgical site infections (SSIs) in adults undergoing elective clean thyroid and breast surgeries in a public hospital in central…
Endometrial Endometrioid Carcinomas With Signet Ring Cells: Report of a Case Series With Detailed Clinical, Pathologic, and Molecular Analysis.
This case series described five patients aged 53–89 years who presented with postmenopausal bleeding and had endometrioid-type endometrial carcinomas containing signet ring cells.
Aspirin after completion of standard adjuvant therapy for colorectal cancer (ASCOLT): A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of aspirin on disease-free survival (DFS) and overall survival (OS) in colorectal cancer patients after standard adjuvant therapy.
Risk, Prevalence and Survival Outcomes of Ovarian Cancer in Women With Endometriosis: The Endocancer Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined the relationship between endometriosis and ovarian cancer risk and survival outcomes in over 500,000 women.
NF2 -mutated Renal Cell Carcinoma: Clinicopathologic and Molecular Characterization of Two Additional Tumors Highlighting Morphologic Heterogeneity and Potential Aggressive Behavior.
Two female patients in their sixth decade presented with incidental solid renal masses measuring 3.2 cm and 3.0 cm. Both tumors exhibited high-grade nuclei and infiltrative growth, but with distinct architectural…
Illustrating the "Quiet Genome" Concept of SMARCA4 -Deficient Uterine Sarcoma Via Whole-Exome Sequencing: A Highly Aggressive Case in a Young Woman.
A 23-year-old woman presented with a uterine mass larger than 15 cm. Histology showed undifferentiated epithelioid cells with rhabdoid features and focal phyllodes-like architecture, without a carcinomatous component.
Hyalinizing Clear Cell Carcinoma of the Lung With Uncommon Distant Cutaneous Metastasis and Aggressive Clinical Course.
A patient presented with primary lung hyalinizing clear cell carcinoma (PLHCCC) characterized by tumor lobules with pale cytoplasm and a mixed stroma.
The Alien Antenna Sign: Physiological ⁶⁸Ga-FAPI Uptake in the Round Ligament.
68 Ga-FAPI PET/CT has emerged as a promising molecular imaging modality targeting cancer-associated fibroblasts, rather than tumor cells.
Hepatic Perfusion-Related Pseudolesion Mimicking Metastasis on 68 Ga-PSMA PET/CT.
A patient with prostate cancer underwent 68 Ga-PSMA PET/CT, revealing a wedge-shaped area of increased PSMA uptake in segment VIII of the liver.
Impact of prospective payment models on cancer patient care: a systematic review.
This systematic review evaluated the impact of prospective payment systems (PPS) on cancer care outcomes, including expenditures, service utilization, quality, and survival, in adult populations.
Effect of Prostate Cancer Screening with Prostate-specific Antigen Testing on Long-term Prostate Cancer-specific Mortality: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
This systematic review and meta-analysis of randomized controlled trials evaluated the impact of prostate-specific antigen (PSA) screening on prostate cancer-specific mortality (PCSM) in 721,607 participants aged 45-80…
Anlotinib plus envafolimab as neoadjuvant therapy in a patient with chemotherapy-refractory advanced endometrial cancer: A case report.
A 51-year-old female presented with advanced endometrial cancer and early-stage lung cancer, suffering from severe urinary retention and poor performance status due to tumor progression.
Low-grade myofibroblastic sarcoma of the orbit in a 68-year-old woman: a case report.
A 68-year-old woman presented with progressive, painless left eye protrusion, accompanied by motility restrictions and dilated conjunctival vessels.
68 Ga-FAPI-04 PET/CT: A "New Kid on the Block" for Evaluation of Stewart-Treves Syndrome.
A 40-year-old woman, who underwent modified radical mastectomy and chemoradiotherapy for triple-negative left breast cancer, presented with increasing lymphedema of the proximal left upper limb of 2 years' duration.
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