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353 articles

August 20268

Case ReportNeurologyOpen access

Downbeat nystagmus: a practical approach based on a clinical case.

Spontaneous downbeat nystagmus (DBN) is the most common form of acquired nystagmus, characterized by a slow upward ocular drift and a corrective downward quick phase.

Arq NeuropsiquiatrAug 13, 2026Read case
Case ReportOphthalmology

TGFBI p.H626R Mutation in a Chinese Family with Lattice Corneal Dystrophy: A Short Report and Literature Review.

A three-generation Chinese family with lattice corneal dystrophy underwent ophthalmic assessment and genetic testing. Sequencing identified a heterozygous TGFBI c.1877A>G (p.His626Arg) mutation in affected family…

Genet Test Mol BiomarkersAug 11, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Comparison of the Effects of Spinal Versus General Anesthesia on the Perioperative Intraocular Pressure: A prospective, randomized clinical trial .

This randomized controlled trial evaluated the effects of spinal versus general anesthesia on intraocular pressure (IOP) in 60 adults undergoing lumbar spine and lower extremity orthopedic surgeries.

Saudi Med JAug 6, 2026Read summary
Clinical ResearchOphthalmology

Intraocular pressure-lowering effects of tetrahydrocannabinol drugs: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the intraocular pressure (IOP)-lowering effects of tetrahydrocannabinol (THC) in 99 patients across five studies.

Can J OphthalmolAug 5, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Diagnostic Accuracy of Teacher-Administered School Vision Screening: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the diagnostic accuracy of teacher-administered vision screenings for refractive errors in children aged 4-18 years, comparing results to gold-standard examinations by…

Ophthalmic Physiol OptAug 5, 2026Read summary
Clinical ResearchOphthalmology

Optical Coherence Tomography-Guided Focal Navigated Laser Photocoagulation in Central Serous Chorioretinopathy: A Non-Inferiority Study.

This prospective nonrandomized noninferiority study evaluated the efficacy and safety of en face optical coherence tomography (OCT)-guided laser photocoagulation in patients with nonresolving central serous…

Am J OphthalmolAug 4, 2026Read summary
Case ReportOphthalmology

Subconjunctival Botulinum Toxin-A Injection as a Treatment for Neuropathic Corneal Pain.

Two patients with chronic neuropathic corneal pain unresponsive to standard treatments received perilimbal subconjunctival injections of botulinum toxin type A.

CorneaAug 4, 2026Read case
Clinical ResearchOphthalmology

Subthreshold micropulse laser and conventional subthreshold laser in diabetic macular edema.

This randomized controlled trial evaluated the effects of subthreshold micropulse laser photocoagulation (SMLP) versus conventional subthreshold laser photocoagulation (SLP) in 66 eyes of 33 patients with clinically…

Photodiagnosis Photodyn TherAug 1, 2026Read summary

July 202616

Clinical ResearchOphthalmology

Cross-Compartment Proteomic Signatures in Human Diabetic Retinopathy: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis synthesized proteomic findings from 28 human diabetic retinopathy studies spanning vitreous, aqueous, plasma or serum, tears, and urine.

Curr Eye ResJul 30, 2026Read summary
Case ReportOphthalmology

Graves' Orbitopathy and Anophthalmia.

This report details four cases of Graves' orbitopathy (GO) in patients with anophthalmia in one eye. All cases exhibited clinical and radiological signs of GO in the anophthalmic eye, with two patients experiencing…

ThyroidJul 29, 2026Read case
Clinical ResearchOphthalmology

Efficacy of different lighting schemes on refractive development and choroidal thickness in school-age children.

This randomized controlled trial examined the effects of a one-year high-illuminance crystal pure full-spectrum lighting scheme on refractive development in 198 school-aged children (6-10 years).

Photodiagnosis Photodyn TherJul 29, 2026Read summary
Clinical ResearchMedical Genetics

The Expanding Phenotypic Spectrum of COL4A1- and COL4A2-Related Disorders: A Systematic Review.

This systematic review analyzed 99 articles to characterize the phenotypic spectrum of COL4A1- and COL4A2-related disorders in 367 patients.

Pediatr NeurolJul 27, 2026Read summary
Clinical ResearchOphthalmology

A hyaluronic acid containing contact lens disinfecting solution can improve contact lens comfort.

This randomized controlled trial evaluated the impact of a hyaluronic acid derivative (HAD) in a multipurpose disinfecting solution on contact lens comfort among wearers with dry eye symptoms.

Cont Lens Anterior EyeJul 27, 2026Read summary
Clinical ResearchOphthalmology

Cost-Effectiveness of Photobiomodulation for Intermediate Dry Age-Related Macular Degeneration: A Model-Based Analysis Using the LIGHTSITE III 24-Month Trial.

This study evaluated the cost-effectiveness of photobiomodulation (PBM) for intermediate dry age-related macular degeneration (AMD) using a model-based analysis from the LIGHTSITE III trial data.

Am J OphthalmolJul 25, 2026Read summary
Clinical ResearchNeurology

A systematic review and meta-analysis of OCT-based ophthalmic changes in amyotrophic lateral sclerosis.

This systematic review and meta-analysis evaluated optical coherence tomography (OCT) findings in amyotrophic lateral sclerosis (ALS) patients.

J NeuroimmunolJul 24, 2026Read summary
Clinical ResearchOncology (Medical)

A systematic review of economic evidence of artificial intelligence in healthcare.

This systematic review evaluated the economic evidence of artificial intelligence (AI) technologies in healthcare, analyzing 98 unique evaluations from 91 records.

Health PolicyJul 21, 2026Read summary
Clinical ResearchOphthalmology

To Investigate the Effect of Combined Use of 0.01% Atropine and 2% Carteolol Hydrochloride Eye Drops on Early-Onset Myopic Control in Western Chinese Children.

This study evaluated myopia progression in children aged 3–8 years in western China using 0.01% atropine alone or combined with 2% carteolol hydrochloride, compared with artificial tears.

Ophthalmic EpidemiolJul 21, 2026Read summary
Case ReportOphthalmology

Posterior ischemic optic neuropathy (PION) secondary to acute orbital hemorrhage: a case report and literature review.

A 49-year-old male developed posterior ischemic optic neuropathy (PION) following acute orbital hemorrhage after cosmetic blepharoplasty.

Arch Soc Esp Oftalmol (Engl Ed)Jul 20, 2026Read case
Clinical ResearchOphthalmology

The effect of Intense Pulsed Light therapy on eyelid bacterial load in contact lens discomfort.

This randomized controlled trial assessed the impact of Intense Pulsed Light (IPL) therapy on eyelid microbiota in symptomatic contact lens wearers.

Cont Lens Anterior EyeJul 19, 2026Read summary
Clinical ResearchOphthalmology

Scleral lens peripheral modifications and regional variations in corneal oedema.

This randomized controlled trial examined the impact of different peripheral scleral lens designs on corneal oedema in nine healthy participants.

Cont Lens Anterior EyeJul 18, 2026Read summary
Clinical ResearchOphthalmology

Advances in Traditional Chinese Medicine for Diabetic Glaucoma: A Systematic Review From Holistic Pathogenesis to Multi-Target Interventions.

This systematic review examines the role of Traditional Chinese Medicine (TCM) in managing diabetic glaucoma, a complication of diabetes characterized by neurodegeneration.

Med Res RevJul 18, 2026Read summary
Case ReportInfectious Diseases

Historical series of paracoccidioidomycosis ocular cases (1923-2025): emphasis on molecular diagnosis of P. lutzii in Midwestern Brazil.

A 53-year-old male logger from Mato Grosso, Brazil, presented with right periorbital edema, eyelid ulceration, and nasal lesions, initially misdiagnosed as leishmaniasis.

Diagn Microbiol Infect DisJul 17, 2026Read case
Clinical ResearchOphthalmology

Safety and tolerability of topical mesenchymal stromal cell secretome in persistent corneal epithelial disease-a phase 1b clinical trial.

This phase 1b clinical trial evaluated the safety and tolerability of topical allogeneic bone marrow-derived mesenchymal stromal cell secretome in patients with persistent corneal epithelial disease.

CytotherapyJul 17, 2026Read summary
Case ReportOphthalmology

Herpes Zoster Ophthalmicus Following Endodontic Treatment: A Case Report.

A 36-year-old male developed herpes zoster ophthalmicus three days after undergoing nonsurgical root canal treatment for his right maxillary first molar.

J EndodJul 16, 2026Read case

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