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1999 articles

September 202624

Clinical ResearchPhysical Medicine & Rehabilitation

Effects of blood flow restriction combined with visual feedback training on lower limb function and the serum levels of BDNF and VEGF in patients with stroke.

This randomized controlled trial examined the effects of blood flow restriction training (BFRT) combined with visual feedback training (VFT) on lower limb function and serum levels of BDNF and VEGF in 40 hospitalized…

PLoS OneSep 28, 2026Read summary
Clinical ResearchCardiology

Stenting Technique and Clinical Outcome in True Bifurcation PCI: Insights From the OCTOBER Trial.

The OCTOBER trial analyzed 1,201 patients undergoing percutaneous coronary intervention for true bifurcation lesions to compare outcomes of 1-stent versus 2-stent techniques.

JACC Cardiovasc IntervSep 28, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Effects of concurrent training sequence on cardiometabolic risk factors in patients with type 2 diabetes: a systematic review and network meta-analysis.

This systematic review and network meta-analysis evaluated the effects of concurrent training sequences on cardiometabolic risk factors in patients with type 2 diabetes mellitus (T2DM).

EndocrineSep 28, 2026Read summary
Case ReportPulmonology

Reversible bilateral cerebellar ataxia resulting from hypercapnic encephalopathy in an undiagnosed patient with obstructive sleep apnoea.

A man in his 40s with morbid obesity and type 2 diabetes presented with early-morning drowsiness and respiratory distress after nocturnal dyspnoea and diuretic use.

BMJ Case RepSep 28, 2026Read case
Clinical ResearchOphthalmology

Comparative study on the clinical effectiveness of low-concentration cyclosporine eye drops in patients with dry eye disease.

This multicenter, randomized, double-blind Phase 2 trial evaluated the efficacy and safety of low-concentration cyclosporine eye drops (SCAI-001 0.01% and 0.02%) versus Restasis (0.05%) in patients with dry eye disease.

PLoS OneSep 28, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Circulating tumour DNA and its clinical relevance in predicting progression-free survival and overall survival in patients with advanced breast cancer: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the prognostic value of circulating tumour DNA (ctDNA) in predicting progression-free survival (PFS) and overall survival (OS) in patients with advanced breast cancer…

Breast Cancer Res TreatSep 28, 2026Read summary
Case ReportNeurosurgery

Ventral Cervical Spinal Schwannoma Presenting as Progressive Myelopathy.

A male in his 20s presented with a two-year history of progressive paraparesis and urinary incontinence. Neurological examination revealed signs of spasticity and reduced lower-limb power.

Ir Med JSep 28, 2026Read case
Clinical ResearchOncology (Medical)Open access

Mindful eating as a supportive intervention for breast cancer survivors: a pilot randomized controlled trial.

This pilot randomized controlled trial assessed whether a six-session mindful eating intervention added to treatment-as-usual (TAU) improved eating behaviors and body composition in breast cancer survivors.

Breast CancerSep 27, 2026Read summary
Clinical ResearchOncology (Medical)

External validation of the NADIR model for early prostate-specific antigen response prediction in enzalutamide-treated metastatic hormone-sensitive prostate cancer: An analysis of the ARCHES trial.

This validation study assessed the NADIR model's ability to predict early prostate-specific antigen (PSA) response in 558 enzalutamide-treated patients from the ARCHES trial.

CancerSep 27, 2026Read summary
Case ReportCardiology

The "Spiked Helmet Sign" on Electrocardiogram Following Left Ventricular Assist Device Implantation: A Case Report.

A 68-year-old male with end-stage ischemic cardiomyopathy underwent left ventricular assist device (LVAD) implantation. Shortly after the procedure, his ECG displayed the 'Spiked Helmet Sign' alongside QTc prolongation.

Ann Noninvasive ElectrocardiolSep 27, 2026Read case
Clinical ResearchObstetrics & Gynecology

Low-intensity pulsed ultrasound to facilitate uterine involution: prospective multicenter study on clinical efficacy and mechanistic insights.

This multicenter, randomized controlled trial evaluated the efficacy of low-intensity pulsed ultrasound (LIPUS) in promoting uterine involution post-delivery among 1,106 women.

Ultrasound Obstet GynecolSep 27, 2026Read summary
Clinical ResearchCardiology

Cost-effectiveness of heart failure pharmacotherapy withdrawal in recovered atrial fibrillation mediated cardiomyopathy: analysis of the WITHDRAW-AF randomized clinical trial.

This economic analysis of the WITHDRAW-AF randomized clinical trial compared heart failure pharmacotherapy withdrawal with continuation in carefully selected patients with recovered atrial fibrillation-mediated…

Int J CardiolSep 27, 2026Read summary
Case ReportMedical GeneticsOpen access

Phenotypic spectrum of 19p13.3 microdeletion: a fatal infant case with severe cardiomegaly and gastrointestinal manifestations.

An 8-month-old female infant presented with multisystemic complications, including congenital heart defects, limb anomalies, macrocephaly, and recurrent pulmonary infections.

Mol Biol RepSep 27, 2026Read case
Case ReportInfectious Diseases

Pulmonary Actinomycosis Diagnosed via BALF mNGS in a 53-Year-Old Nonsmoking Man With Pneumoconiosis and Penicillin-Induced Thrombocytopenia: A Case Report.

A 53-year-old nonsmoking man with pneumoconiosis presented with a month-long history of cough and hemoptysis. Imaging revealed bilateral upper-lung masses and lymphadenopathy, leading to a right upper lobectomy under…

Am J Case RepSep 27, 2026Read case
Clinical ResearchNephrologyOpen access

Longitudinal impact of sodium bicarbonate therapy on health-related quality of life in pre-dialysis chronic kidney disease with metabolic acidosis: a pragmatic trial in Malaysia.

This pragmatic clinical trial evaluated the impact of sodium bicarbonate therapy on health-related quality of life (HRQoL) in 74 pre-dialysis chronic kidney disease (CKD) patients with metabolic acidosis over 18 months.

Qual Life ResSep 27, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Determinants of preterm pre-eclampsia following low-dose aspirin prophylaxis: evidence from stepped-wedge cluster randomized trial in Asia.

This multicenter stepped-wedge cluster randomized trial studied 2919 high-risk pregnant women receiving low-dose aspirin prophylaxis to identify risk factors for preterm pre-eclampsia (PE).

Ultrasound Obstet GynecolSep 27, 2026Read summary
Clinical ResearchCardiologyOpen access

GLP-1 Receptor Agonists in Heart Failure: A Systematic Review and Meta-analysis with Phenotype-Specific Effects and Dual Analytical Frameworks.

This systematic review and random-effects meta-analysis assessed GLP-1 receptor agonists across heart-failure phenotypes and trial types, including 14 trials and 15,882 patients with heart failure.

DrugsSep 26, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Virtual reality as a non-pharmacological adjuvant for anxiety in oncology care: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of virtual reality (VR) interventions for managing anxiety in cancer patients.

Support Care CancerSep 26, 2026Read summary
Clinical ResearchGeriatrics

Effect of Multi-Modal Training in Patients With Mild Cognitive Impairment: A Randomized Controlled Pilot Trial.

This pilot randomized controlled trial evaluated the effects of a 24-week multi-modal training program on cognitive function in 65 older adults with mild cognitive impairment (MCI).

Med Sci MonitSep 26, 2026Read summary
Clinical ResearchOncology (Medical)

Long-term outcome after partial breast irradiation with interstitial multi-catheter high-dose-rate brachytherapy: Results from a Phase II prospective study with extended follow-up.

This prospective observational Phase II study assessed late toxicity, cosmesis, and cancer outcomes after partial breast irradiation with interstitial multi-catheter high-dose-rate brachytherapy.

BrachytherapySep 26, 2026Read summary
Clinical ResearchUrologyOpen access

Exploring the impact of artificial intelligence on radiation dose reduction in urological imaging: a systematic review from EAU endourology.

This systematic review evaluated the impact of artificial intelligence (AI) on radiation dose reduction in urological CT imaging.

World J UrolSep 26, 2026Read summary
Case ReportGastroenterology

Phlegmonous Gastritis Refractory to Antibiotics with Subsequent Improvement on Empiric Quadruple Therapy.

A 59-year-old woman presented with two days of severe nausea, vomiting, and inability to tolerate oral intake while on chronic proton-pump inhibitor therapy.

R I Med J (2013)Sep 26, 2026Read case
Case ReportNeurology

Recognition and Treatment of Concurrent Amyotrophic Lateral Sclerosis and Multiple Sclerosis.

A patient with a long-standing history of multiple sclerosis presented with overlapping progressive symptoms. Upon further evaluation, the diagnosis of amyotrophic lateral sclerosis was established, highlighting the…

R I Med J (2013)Sep 26, 2026Read case
Case ReportOncology (Medical)

Mucinous Adenocarcinoma Arising in a Mature Ovarian Teratoma.

A woman in her 30s presented with a 19 cm right ovarian mass. She underwent extensive surgical intervention, including right salpingo-oophorectomy and lymphadenectomy.

R I Med J (2013)Sep 26, 2026Read case

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