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434 articles

June 20264

May 202620

Clinical ResearchCardiology

Outcomes in Obese Adult Venoarterial Extracorporeal Membrane Oxygenation: A Systematic Review.

This systematic review evaluated outcomes in obese adults undergoing venoarterial ECMO, analyzing data from five studies with 1,196 patients.

J Cardiothorac Vasc AnesthMay 30, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Efficacy and safety of durvalumab with or without tremelimumab in the treatment of metastatic non-small cell lung cancer: a meta-analysis of randomized controlled trials.

This meta-analysis evaluated the efficacy and safety of durvalumab with or without tremelimumab in 2726 patients with metastatic non-small cell lung cancer (NSCLC).

Proc (Bayl Univ Med Cent)May 29, 2026Read summary
Clinical ResearchOncology (Medical)

Lorlatinib versus crizotinib as first-line treatment for advanced ALK-positive non-small-cell lung cancer: 7-year update from the phase III CROWN study.

The phase III CROWN study evaluated lorlatinib versus crizotinib in treatment-naive patients with advanced ALK-positive non-small-cell lung cancer (NSCLC).

Ann OncolMay 29, 2026Read summary
Clinical ResearchInfectious Diseases

Efficacy and safety of a 4-month quabodepistat, delamanid, and bedaquiline regimen for drug-susceptible pulmonary tuberculosis: a multicentre, open-label, randomised, proof-of-concept, non-inferiority, phase 2b/c trial.

This multicentre, open-label, randomised, proof-of-concept trial evaluated a 4-month regimen of delamanid, bedaquiline, and quabodepistat (DBQ) in 122 adults with drug-susceptible pulmonary tuberculosis.

Lancet Infect DisMay 29, 2026Read summary
Clinical ResearchAllergy & Immunology

Phase Ib/II Study of Preliminary Efficacy, Safety and Pharmacodynamics of MG-K10, a Humanised Monoclonal Antibody Targeting IL-4Rα, in Adult Chinese Patients With Asthma.

This Phase Ib/II randomized controlled trial evaluated the efficacy, safety, and pharmacodynamics of MG-K10, a monoclonal antibody targeting IL-4Rα, in Chinese adults with moderate-to-severe asthma.

Clin Exp AllergyMay 29, 2026Read summary
Clinical ResearchPulmonologyOpen access

Hair analysis of formoterol as a novel tool to assess long-term inhalation medication adherence: Data from the TRICOLON trial.

This randomized controlled trial investigated the use of hair analysis to measure long-term adherence to inhaled formoterol in patients with COPD.

Br J Clin PharmacolMay 28, 2026Read summary
Clinical ResearchNeurology

Obstructive sleep apnea and idiopathic intracranial hypertension: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed the prevalence of obstructive sleep apnea (OSA) in adults with idiopathic intracranial hypertension (IIH) using polysomnography and the Berlin Questionnaire.

Can J OphthalmolMay 27, 2026Read summary
Clinical ResearchInfectious Diseases

Diagnostic accuracy of metagenomic next-generation sequencing for invasive pulmonary aspergillosis: A systematic review and meta-analysis.

This meta-analysis evaluated the diagnostic accuracy of metagenomic next-generation sequencing (mNGS) for invasive pulmonary aspergillosis (IPA) across twelve studies.

Int J Infect DisMay 27, 2026Read summary
Clinical ResearchPulmonology

Efficacy and potential mechanisms of alkaloids in animal models for pulmonary fibrosis: a study integrating preclinical systematic review and meta-analysis, network pharmacology and molecular docking.

This meta-analysis and systematic review evaluated the efficacy of alkaloids in treating pulmonary fibrosis (PF) using data from 35 randomized controlled trials involving 548 animals.

Int ImmunopharmacolMay 27, 2026Read summary
Clinical ResearchPulmonology

Clinical efficacy of chronotherapy-based auricular acupoint therapy combined with CPAP in comorbid obstructive sleep apnea and insomnia.

This randomized controlled trial evaluated the efficacy of chronotherapy-based auricular acupoint therapy combined with CPAP in 114 patients with comorbid obstructive sleep apnea and insomnia (COMISA).

Explore (NY)May 25, 2026Read summary
Clinical ResearchPediatricsOpen access

Extended Continuous Positive Airway Pressure in Infants Born Preterm Decreases Intermittent Hypoxemia: A Secondary Analysis of a Randomized Controlled Trial.

This secondary analysis of a randomized controlled trial evaluated the effects of extended continuous positive airway pressure (eCPAP) versus discontinued CPAP (dCPAP) on intermittent hypoxemia (IH) in stable preterm…

J PediatrMay 25, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Comparison of PD-L1 expression between biopsy specimens and surgical resection specimens in non-small cell lung cancer: a meta-analysis.

This meta-analysis compared PD-L1 positivity in biopsy and surgical resection specimens from patients with non-small cell lung cancer, drawing on 13 studies involving 966 patients.

Clin Transl OncolMay 24, 2026Read summary
Clinical ResearchPulmonologyOpen access

Fan Therapy for Alleviating Dyspnea in Adults: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the effectiveness of fan therapy for alleviating dyspnea in adults, analyzing 15 studies with 623 participants.

J Clin NursMay 22, 2026Read summary
Clinical ResearchRadiology (Diagnostic)Open access

Long-Term Outcomes After Proton Therapy Versus Intensity Modulated Photon Radiation Therapy With Concurrent Chemotherapy for Locally Advanced Non-Small Cell Lung Cancer: Post Hoc Analysis of a Prospective Randomized Trial.

This post hoc analysis of a prospective randomized trial compared long-term outcomes after passive scattering proton therapy (PSPT) versus intensity modulated photon radiation therapy (IMRT), each given with concurrent…

Int J Radiat Oncol Biol PhysMay 21, 2026Read summary
Clinical ResearchAllergy & Immunology

Glucagon-Like Peptide-1 Receptor Agonists in Asthma and Obesity-Associated Asthma: A Systematic Review of Clinical Outcomes and Translational Mechanisms.

This systematic review evaluated the effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on asthma outcomes, particularly in individuals with obesity and type 2 diabetes.

J Allergy Clin Immunol PractMay 20, 2026Read summary
Clinical ResearchPulmonologyOpen access

Phase-resolved functional lung MRI detects single-dose and sustained bronchodilator responses in COPD in a randomized crossover trial.

This randomized controlled trial evaluated the effects of tiotropium/olodaterol on phase-resolved functional lung MRI parameters in 32 patients with moderate-to-severe COPD.

Eur RadiolMay 20, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Efficacy of BiPAP/CPAP versus COT in patients with obstructive sleep apnea or obesity undergoing sedated gastroenteroscopy: a meta-analysis.

This meta-analysis evaluated the efficacy of bilevel or continuous positive airway pressure (BiPAP/CPAP) versus conventional oxygen therapy (COT) in preventing hypoxemia during sedated gastroenteroscopy in patients with…

J AnesthMay 20, 2026Read summary
Case ReportRheumatology

A Rare Case of Four-year Complete Metabolic Response in Multisystem Anti-Jo-1 Antisynthetase Syndrome Assessed by 18 F-FDG PET/CT.

A patient with anti-Jo-1 positive antisynthetase syndrome presented with muscular, articular, cutaneous, and pulmonary involvement.

Clin Nucl MedMay 19, 2026Read case
Case ReportInfectious Diseases

From chronic abscess to acute respiratory distress syndrome (ARDS): A case of recurrent melioidosis in Sri Lanka.

A 31-year-old previously healthy man presented with a recurrent chest wall abscess and developed fulminant pneumonia, leading to acute respiratory distress syndrome (ARDS) eight months after incomplete treatment for…

Trop DoctMay 19, 2026Read case
Clinical ResearchPulmonology

Steroid Therapy in Community-Acquired Pneumonia: An Updated Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the impact of corticosteroid therapy on mortality and morbidity in 5,866 adults with community-acquired pneumonia (CAP).

Heart LungMay 17, 2026Read summary

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